Youssef Sari
- Pharmacology & Experimental Therapeutics, & joint appointment in Medicinal & Biological Chemistry, Pharmacology , College of Pharmacy and Pharmaceutical Sciences
Contact Info
Publications
selected publications
-
Article (Faculty180)
-
2024Activation of α7 nicotinic receptors attenuated hyperalgesia and anxiety induced by palatable obesogenic diet withdrawal. Journal of pharmacological sciences. 156:86-101.
-
2024Adolescent alcohol drinking interaction with the gut microbiome: implications for adult alcohol use disorder. Advances in drug and alcohol research. 4.
-
2024Ceftriaxone and MC-100093 mitigate fentanyl-induced cardiac injury in mice: Preclinical investigation of its underlying molecular mechanisms. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. 32:102148.
-
2024
-
2024
-
2024Effects of novel beta-lactam, MC-100093, and ceftriaxone on astrocytic glutamate transporters and neuroinflammatory factors in nucleus accumbens of C57BL/6 mice exposed to escalated doses of morphine. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. 32:102108.
-
2023Intrarenal Dopaminergic System Is Dysregulated in SS- Rats. Biomedicines. 11.
-
2022Ceftriaxone as a Novel Therapeutic Agent for Hyperglutamatergic States: Bridging the Gap Between Preclinical Results and Clinical Translation. Frontiers in neuroscience. 16:841036.
-
2022Effects of a Novel Beta Lactam Compound, MC-100093, on the Expression of Glutamate Transporters/Receptors and Ethanol Drinking Behavior of Alcohol-Preferring Rats. The Journal of pharmacology and experimental therapeutics. 383:208-216.
-
2022Effects of waterpipe tobacco smoke and ceftriaxone treatment on the expression of endocannabinoid receptors in mesocorticolimbic brain regions. Brain research bulletin. 185:56-63.
-
2022Interactive role of acid sensing ion channels and glutamatergic system in opioid dependence. Neuroscience and biobehavioral reviews. 135:104581.
-
2022
-
2021
-
2021E-cigarette aerosols containing nicotine modulate nicotinic acetylcholine receptors and astroglial glutamate transporters in mesocorticolimbic brain regions of chronically exposed mice. Chemico-biological interactions. 333:109308.
-
2021Effect of Modulation of the Astrocytic Glutamate Transporters' Expression on Cocaine-Induced Reinstatement in Male P Rats Exposed to Ethanol. Alcohol and alcoholism (Oxford, Oxfordshire). 56:210-219.
-
2020Effects of Cocaine Exposure on Astrocytic Glutamate Transporters and Relapse-Like Ethanol-Drinking Behavior in Male Alcohol-Preferring Rats. Alcohol and alcoholism (Oxford, Oxfordshire). 55:254-263.
-
2020Effects of chronic ethanol consumption on the expression of GLT-1 and neuroplasticity-related proteins in the nucleus accumbens of alcohol-preferring rats. Brain research bulletin. 165:272-280.
-
2020Overview of Therapeutic Drugs and Methods for the Treatment of Parkinson's Disease. CNS & neurological disorders drug targets. 19:195-206.
-
2019Alcohol and Cocaine Exposure Modulates ABCB1 and ABCG2 Transporters in Male Alcohol-Preferring Rats. Molecular neurobiology. 56:1921-1932.
-
2019Alcohol and cocaine exposure modulates ABCB1 and ABCG2 transporters in male alcohol preferring rats. Molecular Neurobiology. 56:1921-1932.
-
2019
-
2019Effects of Clavulanic Acid Treatment on Reinstatement to Methamphetamine, Glial Glutamate Transporters, and mGluR 2/3 Expression in P Rats Exposed to Ethanol. Journal of molecular neuroscience : MN. 67:1-15.
-
2019SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs. Journal of enzyme inhibition and medicinal chemistry. 34:863-876.
-
2019β-lactams modulate astroglial glutamate transporters and attenuate dependence to CP 55,940, a CB1 receptor agonist, in rat model. Behavioural brain research. 359:709-718.
-
2018A computerized exposure system for animal models to optimize nicotine delivery into the brain through inhalation of electronic cigarette vapors or cigarette smoke. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. 26:622-628.
-
2018Effects of ceftriaxone on hydrocodone seeking behavior and glial glutamate transporters in P rats. Behavioural brain research. 347:368-376.
-
2018Modulation of the ATP-Binding Cassette B1 Transporter by Neuro-Inflammatory Cytokines: Role in the Pathogenesis of Alzheimer's Disease. Frontiers in pharmacology. 9:658.
-
2018Peri-adolescent drinking of ethanol and/or nicotine modulates astroglial glutamate transporters and metabotropic glutamate receptor-1 in female alcohol-preferring rats. Pharmacology, biochemistry, and behavior. 170:44-55.
-
2018Role of glutamatergic system and mesocorticolimbic circuits in alcohol dependence. Progress in neurobiology. 171:32-49.
-
2017Alcohol consumption impairs the ependymal cilia motility in the brain ventricles. Scientific reports. 7:13652.
-
2017Commentary: Targeting NMDA Receptor and Serotonin Transporter for the Treatment of Comorbid Alcohol Dependence and Depression. Alcoholism, clinical and experimental research. 41:275-278.
-
2017Effects of Administered Ethanol and Methamphetamine on Glial Glutamate Transporters in Rat Striatum and Hippocampus. Journal of molecular neuroscience : MN. 61:343-350.
-
2017Effects of chronic inhalation of electronic cigarettes containing nicotine on glial glutamate transporters and α-7 nicotinic acetylcholine receptor in female CD-1 mice. Progress in neuro-psychopharmacology & biological psychiatry. 77:1-8.
-
2017Effects of orally administered Augmentin on glutamate transporter 1, cystine-glutamate exchanger expression and ethanol intake in alcohol-preferring rats. Behavioural brain research. 320:316-322.
-
2017Effects of repeated cocaine exposure and withdrawal on voluntary ethanol drinking, and the expression of glial glutamate transporters in mesocorticolimbic system of P rats. Molecular and cellular neurosciences. 82:58-65.
-
2017Metabotropic and ionotropic glutamate receptors as potential targets for the treatment of alcohol use disorder. Neuroscience and biobehavioral reviews. 77:14-31.
-
2017Modulatory effects of Ampicillin/Sulbactam on glial glutamate transporters and metabotropic glutamate receptor 1 as well as reinstatement to cocaine-seeking behavior. Behavioural brain research. 332:288-298.
-
2017Rat animal models for screening medications to treat alcohol use disorders. Neuropharmacology. 122:201-243.
-
2017
-
2016A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction. International review of neurobiology. 126:179-261.
-
2016Alcohol Interactions with Psychostimulants: An Overview of Animal and Human Studies. Journal of addiction research & therapy. 7.
-
2016Binge ethanol withdrawal: Effects on post-withdrawal ethanol intake, glutamate-glutamine cycle and monoamine tissue content in P rat model. Behavioural brain research. 303:120-5.
-
2016Development and evaluation of a calcium alginate based oral ceftriaxone sodium formulation. Progress in biomaterials. 5:117-133.
-
2016
-
2016Effects of Benzodiazepines on Acinar and Myoepithelial Cells. Frontiers in pharmacology. 7:173.
-
2016Effects of Ceftriaxone on Glial Glutamate Transporters in Wistar Rats Administered Sequential Ethanol and Methamphetamine. Frontiers in neuroscience. 10:427.
-
2016
-
2016Targeting Dopaminergic System for Treating Nicotine Dependence. Central nervous system agents in medicinal chemistry. 16:137-42.
-
2016Targeting glutamate homeostasis for potential treatment of nicotine dependence. Brain research bulletin. 121:1-8.
-
2015Designing Novel Nanoformulations Targeting Glutamate Transporter Excitatory Amino Acid Transporter 2: Implications in Treating Drug Addiction. Journal of personalized nanomedicine. 1:3-9.
-
2015
-
2015Effects of ampicillin on cystine/glutamate antiporter and glutamate transporter 1 isoforms as well as ethanol drinking in male P rats. Neuroscience letters. 600:148-52.
-
2015Effects of ceftriaxone on GLT1 isoforms, xCT and associated signaling pathways in P rats exposed to ethanol. Psychopharmacology. 232:2333-42.
-
2015Histomorphometric analysis of salivary gland in wistar rats treated chronically with two benzodiazepines. Current pharmaceutical biotechnology. 16:573-8.
-
2015Monoamine Oxidase Inhibitors Extracted from Tobacco Smoke as Neuroprotective Factors for Potential Treatment of Parkinson's Disease. CNS & neurological disorders drug targets. 14:777-85.
-
2015Targeting glutamate uptake to treat alcohol use disorders. Frontiers in neuroscience. 9:144.
-
2014Effectiveness of Ceftriaxone Treatment in Preventing Relapse-like Drinking Behavior Following Long-term Ethanol Dependence in P Rats. Journal of addiction research & therapy. 5.
-
2014Effects of MS-153 on chronic ethanol consumption and GLT1 modulation of glutamate levels in male alcohol-preferring rats. Frontiers in behavioral neuroscience. 8:366.
-
2014Effects of ceftriaxone on chronic ethanol consumption: a potential role for xCT and GLT1 modulation of glutamate levels in male P rats. Journal of molecular neuroscience : MN. 54:71-7.
-
2014Effects of ceftriaxone on ethanol intake: a possible role for xCT and GLT-1 isoforms modulation of glutamate levels in P rats. Psychopharmacology. 231:4049-57.
-
2014Effects of ceftriaxone on systemic and central expression of anti- and pro-inflammatory cytokines in alcohol-preferring (P) rats exposed to ethanol. Alcohol and alcoholism (Oxford, Oxfordshire). 49:689.
-
2014Potential therapeutic drugs and methods for the treatment of amyotrophic lateral sclerosis. Current medicinal chemistry. 21:3583-93.
-
2014Role of glutamate transporter 1 in the attenuation of alcohol intake. Frontiers in neuroscience. 8:200.
-
2014The 5-HT7 receptor as a potential target for treating drug and alcohol abuse. Frontiers in neuroscience. 8:448.
-
2014Therapeutic perspectives of drugs targeting Toll-like receptors based on immune physiopathology theory of Alzheimer's disease. CNS & neurological disorders drug targets. 13:909-20.
-
2014Three types of ependymal cells with intracellular calcium oscillation are characterized by distinct cilia beating properties. Journal of neuroscience research. 92:1199-204.
-
2013Ceftriaxone treatment affects the levels of GLT1 and ENT1 as well as ethanol intake in alcohol-preferring rats. Journal of molecular neuroscience : MN. 51:779-87.
-
2013Ceftriaxone, a beta-lactam antibiotic, attenuates relapse-like ethanol-drinking behavior in alcohol-preferring rats. Journal of psychopharmacology (Oxford, England). 27:541-9.
-
2013Experimental methods for testing the effects of neurotrophic peptide, ADNF-9, against alcohol-induced apoptosis during pregnancy in c57bl/6 mice. Journal of visualized experiments : JoVE. e50092.
-
2013Neurotrophic Peptides: Potential Drugs for Treatment of Amyotrophic Lateral Sclerosis and Alzheimer's disease. Open journal of neuroscience. 3.
-
2013Neurotrophic peptides, ADNF-9 and NAP, prevent alcohol-induced apoptosis at midgestation in fetal brains of C57BL/6 mouse. Journal of molecular neuroscience : MN. 49:150-6.
-
2013Role of 5-hydroxytryptamine 1B (5-HT1B) receptors in the regulation of ethanol intake in rodents. Journal of psychopharmacology (Oxford, England). 27:3-12.
-
2012Adenosine and glutamate signaling in neuron-glial interactions: implications in alcoholism and sleep disorders. Alcoholism, clinical and experimental research. 36:1117-25.
-
2012Cilostazol prevents endothelin-induced smooth muscle constriction and proliferation. PloS one. 7:e44476.
-
2012Glutamate transporter 1: target for the treatment of alcohol dependence. Current medicinal chemistry. 19:5148-56.
-
2012
-
2011Ceftriaxone, a beta-lactam antibiotic, reduces ethanol consumption in alcohol-preferring rats. Alcohol and alcoholism (Oxford, Oxfordshire). 46:239-46.
-
2011Huntington's Disease: From Mutant Huntingtin Protein to Neurotrophic Factor Therapy. International journal of biomedical science : IJBS. 7:89-100.
-
2011Neuroprotective peptide ADNF-9 in fetal brain of C57BL/6 mice exposed prenatally to alcohol. Journal of biomedical science. 18:77.
-
2011Potential drugs and methods for preventing or delaying the progression of Huntington's disease. Recent patents on CNS drug discovery. 6:80-90.
-
2011Role of the serotonergic system in alcohol dependence: from animal models to clinics. Progress in molecular biology and translational science. 98:401-43.
-
2010Alteration of selective neurotransmitters in fetal brains of prenatally alcohol-treated C57BL/6 mice: quantitative analysis using liquid chromatography/tandem mass spectrometry. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 28:263-9.
-
2010Ceftriaxone-induced up-regulation of cortical and striatal GLT1 in the R6/2 model of Huntington's disease. Journal of biomedical science. 17:62.
-
2010
-
2009
-
2009Upregulation of GLT1 attenuates cue-induced reinstatement of cocaine-seeking behavior in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29:9239-43.
-
2008
-
2006Effects of chronic alcohol and repeated deprivations on dopamine D1 and D2 receptor levels in the extended amygdala of inbred alcohol-preferring rats. Alcoholism, clinical and experimental research. 30:46-56.
-
2006Glutamate and dopamine synaptic terminals in extended amygdala after 14-week chronic alcohol drinking in inbred alcohol-preferring rats. Alcohol (Fayetteville, N.Y.). 39:39-49.
-
2006Structural and functional modifications in glutamateric synapses following prolonged ethanol exposure. Alcoholism, clinical and experimental research. 30:368-76.
-
2005Fetal alcohol exposure reduces serotonin innervation and compromises development of the forebrain along the serotonergic pathway. Alcoholism, clinical and experimental research. 29:141-9.
-
2004A neuroprotective peptide antagonizes fetal alcohol exposure-compromised brain growth. Journal of molecular neuroscience : MN. 24:189-99.
-
2004Neurotransmitters and substances of abuse: effects on adult neurogenesis. Current neurovascular research. 1:251-60.
-
2004Prenatal alcohol exposure causes long-term serotonin neuron deficit in mice. Alcoholism, clinical and experimental research. 28:941-8.
-
2004Selective serotonin reuptake inhibitor disrupts organization of thalamocortical somatosensory barrels during development. Brain research. Developmental brain research. 150:151-61.
-
2004Serotonin1B receptors: from protein to physiological function and behavior. Neuroscience and biobehavioral reviews. 28:565-82.
-
2003Moderate alcohol exposure compromises neural tube midline development in prenatal brain. Brain research. Developmental brain research. 144:43-55.
-
2003Serotonin and its transporter on proliferation of fetal heart cells. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 21:417-24.
-
2002Deviations in brain early serotonergic development as a result of fetal alcohol exposure. Neurotoxicity research. 4:337-42.
-
2001Alcohol deters the outgrowth of serotonergic neurons at midgestation. Journal of biomedical science. 8:119-25.
-
2001Fetal alcohol effects: mechanisms and treatment. Alcoholism, clinical and experimental research. 25:110S-116S.
-
2001Prenatal alcohol exposure retards the migration and development of serotonin neurons in fetal C57BL mice. Brain research. Developmental brain research. 126:147-55.
-
2000Expression of serotonin transporter protein in developing rat brain. Brain research. Developmental brain research. 119:33-45.
-
1999Limited inhibition of 5-HT1A receptor expression in the rat brain by antisense RNA and oligodesoxynucleotides. Neuroscience letters. 259:191-5.
-
1997Light and electron microscopic immunocytochemical visualization of 5-HT1B receptors in the rat brain. Brain research. 760:281-6.
-
-
Article (Web of Science)
-
2021Ceftriaxone Reduces Waterpipe Tobacco Smoke Withdrawal-induced Anxiety in rats via Modulating the Expression of TNF-a/NFB, Nrf2, and GLT-1. NEUROSCIENCE. 463:128-142.Full Text via DOI: 10.1016/j.neuroscience.2021.03.030 PMID: 33836247
-
2021Effect of Modulation of the Astrocytic Glutamate Transporters' Expression on Cocaine-Induced Reinstatement in Male P Rats Exposed to Ethanol. ALCOHOL AND ALCOHOLISM. 56:210-219.Full Text via DOI: 10.1093/alcalc/agaa104 PMID: 33063090
-
2021E-cigarette aerosols containing nicotine modulate nicotinic acetylcholine receptors and astroglial glutamate transporters in mesocorticolimbic brain regions of chronically exposed mice. CHEMICO-BIOLOGICAL INTERACTIONS. 333.Full Text via DOI: 10.1016/j.cbi.2020.109308 PMID: 33242460
-
2020Effects of 3-Month Exposure to E-Cigarette Aerosols on Glutamatergic Receptors and Transporters in Mesolimbic Brain Regions of Female C57BL/6 Mice. TOXICS. 8.Full Text via DOI: 10.3390/toxics8040095 PMID: 33137879
-
2020Effects of chronic ethanol consumption on the expression of GLT-1 and neuroplasticity-related proteins in the nucleus accumbens of alcohol-preferring rats. BRAIN RESEARCH BULLETIN. 165:272-280.Full Text via DOI: 10.1016/j.brainresbull.2020.10.012 PMID: 33075417
-
2020Ampicillin/Sulbactam Treatment Modulates NMDA Receptor NR2B Subunit and Attenuates Neuroinflammation and Alcohol Intake in Male High Alcohol Drinking Rats. BIOMOLECULES. 10.Full Text via DOI: 10.3390/biom10071030 PMID: 32664441
-
2020Chronic Ethanol Consumption Alters Glucocorticoid Receptor Isoform Expression in Stress Neurocircuits and Mesocorticolimbic Brain Regions of Alcohol-Preferring Rats. NEUROSCIENCE. 437:107-116.Full Text via DOI: 10.1016/j.neuroscience.2020.04.033 PMID: 32353460
-
2020Effects of Cocaine Exposure on Astrocytic Glutamate Transporters and Relapse-Like Ethanol-Drinking Behavior in Male Alcohol-Preferring Rats. ALCOHOL AND ALCOHOLISM. 55:254-263.Full Text via DOI: 10.1093/alcalc/agaa010 PMID: 32099993
-
2019Effects of Chronic Inhalation of Electronic Cigarette Vapor Containing Nicotine on Neurotransmitters in the Frontal Cortex and Striatum of C57BL/6 Mice. FRONTIERS IN PHARMACOLOGY. 10.Full Text via DOI: 10.3389/fphar.2019.00885 PMID: 31456684
-
2019Alcohol and Cocaine Exposure Modulates ABCB1 and ABCG2 Transporters in Male Alcohol-Preferring Rats. MOLECULAR NEUROBIOLOGY. 56:1921-1932.Full Text via DOI: 10.1007/s12035-018-1153-2
-
2019beta-lactams modulate astroglial glutamate transporters and attenuate dependence to CP 55,940, a CB1 receptor agonist, in rat model. BEHAVIOURAL BRAIN RESEARCH. 359:709-718.Full Text via DOI: 10.1016/j.bbr.2018.09.015
-
2019Effects of Clavulanic Acid Treatment on Reinstatement to Methamphetamine, Glial Glutamate Transporters, and mGluR 2/3 Expression in P Rats Exposed to Ethanol. JOURNAL OF MOLECULAR NEUROSCIENCE. 67:1-15.Full Text via DOI: 10.1007/s12031-018-1194-z
-
2019SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. 34:863-876.Full Text via DOI: 10.1080/14756366.2019.1593158 PMID: 30915862
-
2018Effects of ceftriaxone on hydrocodone seeking behavior and glial glutamate transporters in P rats. BEHAVIOURAL BRAIN RESEARCH. 347:368-376.Full Text via DOI: 10.1016/j.bbr.2018.03.043
-
2018Peri-adolescent drinking of ethanol and/or nicotine modulates astroglial glutamate transporters and metabotropic glutamate receptor-1 in female alcohol-preferring rats. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR. 170:44-55.Full Text via DOI: 10.1016/j.pbb.2018.05.006
-
2018Effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in Wistar rats. NEUROSCIENCE LETTERS. 665:61-66.Full Text via DOI: 10.1016/j.neulet.2017.11.043
-
2017Alcohol consumption impairs the ependymal cilia motility in the brain ventricles. SCIENTIFIC REPORTS. 7.Full Text via DOI: 10.1038/s41598-017-13947-3
-
2017beta-Lactamase inhibitor, clavulanic acid, attenuates ethanol intake and increases glial glutamate transporters expression in alcohol preferring rats. NEUROSCIENCE LETTERS. 657:140-145.Full Text via DOI: 10.1016/j.neulet.2017.08.013
-
2017Modulatory effects of Ampicillin/Sulbactam on glial glutamate transporters and metabotropic glutamate receptor 1 as well as reinstatement to cocaine-seeking behavior. BEHAVIOURAL BRAIN RESEARCH. 332:288-298.Full Text via DOI: 10.1016/j.bbr.2017.06.017
-
2017Effects of chronic inhalation of electronic cigarettes containing nicotine on glial glutamate transporters and alpha-7 nicotinic acetylcholine receptor in female CD-1 mice. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 77:1-8.Full Text via DOI: 10.1016/j.pnpbp.2017.03.017
-
2017Effects of repeated cocaine exposure and withdrawal on voluntary ethanol drinking, and the expression of glial glutamate transporters in mesocorticolimbic system of P rats. MOLECULAR AND CELLULAR NEUROSCIENCE. 82:58-65.Full Text via DOI: 10.1016/j.mcn.2017.04.008
-
2017Effects of Administered Ethanol and Methamphetamine on Glial Glutamate Transporters in Rat Striatum and Hippocampus. JOURNAL OF MOLECULAR NEUROSCIENCE. 61:343-350.Full Text via DOI: 10.1007/s12031-016-0859-8
-
2017Effects of orally administered Augmentin on glutamate transporter 1, cystine-glutamate exchanger expression and ethanol intake in alcohol-preferring rats. BEHAVIOURAL BRAIN RESEARCH. 320:316-322.Full Text via DOI: 10.1016/j.bbr.2016.12.016
-
2016Effects of repeated high-dose methamphetamine and ceftriaxone post-treatments on tissue content of dopamine and serotonin as well as glutamate and glutamine. NEUROSCIENCE LETTERS. 634:25-31.Full Text via DOI: 10.1016/j.neulet.2016.09.058
-
2016Effects of Ceftriaxone on Glial Glutamate Transporters in Wistar Rats Administered Sequential Ethanol and Methamphetamine. FRONTIERS IN NEUROSCIENCE. 10.Full Text via DOI: 10.3389/fnins.2016.00427
-
2016Effects of Benzodiazepines on Acinar and Myoepithelial Cells. FRONTIERS IN PHARMACOLOGY. 7.Full Text via DOI: 10.3389/fphar.2016.00173
-
2016EFFECTS OF CEFTRIAXONE ON ETHANOL, NICOTINE OR SUCROSE INTAKE BY ALCOHOL-PREFERRING (P) RATS AND ITS ASSOCIATION WITH GLT-1 EXPRESSION. NEUROSCIENCE. 326:117-125.Full Text via DOI: 10.1016/j.neuroscience.2016.04.004
-
2016Effects of Amoxicillin and Augmentin on Cystine-Glutamate Exchanger and Glutamate Transporter 1 Isoforms as well as Ethanol Intake in Alcohol-Preferring Rats. FRONTIERS IN NEUROSCIENCE. 10.Full Text via DOI: 10.3389/fnins.2016.00171
-
2016Binge ethanol withdrawal: Effects on post-withdrawal ethanol intake, glutamate-glutamine cycle and monoamine tissue content in P rat model. BEHAVIOURAL BRAIN RESEARCH. 303:120-125.Full Text via DOI: 10.1016/j.bbr.2016.01.052
-
2016Effects of cefazolin and cefoperazone on glutamate transporter 1 isoforms and cystine/glutamate exchanger as well as alcohol drinking behavior in male alcohol-preferring rats. BRAIN RESEARCH. 1634:150-157.Full Text via DOI: 10.1016/j.brainres.2016.01.007
-
2016Development and evaluation of a calcium alginate based oral ceftriaxone sodium formulation. Progress in Biomaterials. 5:117-133.Full Text via DOI: 10.1007/s40204-016-0051-9
-
2015Amoxicillin and amoxicillin/clavulanate reduce ethanol intake and increase GLT-1 expression as well as AKT phosphorylation in mesocorticolimbic regions. BRAIN RESEARCH. 1622:397-408.Full Text via DOI: 10.1016/j.brainres.2015.07.008
-
2015Ceftriaxone attenuates ethanol drinking and restores extracellular glutamate concentration through normalization of GLT-1 in nucleus accumbens of male alcohol-preferring rats. NEUROPHARMACOLOGY. 97:67-74.Full Text via DOI: 10.1016/j.neuropharm.2015.05.009
-
2015Effects of ampicillin on cystine/glutamate antiporter and glutamate transporter 1 isoforms as well as ethanol drinking in male P rats. NEUROSCIENCE LETTERS. 600:148-152.Full Text via DOI: 10.1016/j.neulet.2015.06.015
-
2015Effects of ceftriaxone on GLT1 isoforms, xCT and associated signaling pathways in P rats exposed to ethanol. PSYCHOPHARMACOLOGY. 232:2333-2342.Full Text via DOI: 10.1007/s00213-015-3868-3
-
2015EFFECTS OF AMPICILLIN, CEFAZOLIN AND CEFOPERAZONE TREATMENTS ON GLT-1 EXPRESSIONS IN THE MESOCORTICOLIMBIC SYSTEM AND ETHANOL INTAKE IN ALCOHOL-PREFERRING RATS. NEUROSCIENCE. 295:164-174.Full Text via DOI: 10.1016/j.neuroscience.2015.03.038
-
2015Effects of (R)-(-)-5-Methyl-1-Nicotinoyl-2-Pyrazoline on Glutamate Transporter 1 and Cysteine/Glutamate Exchanger as Well as Ethanol Drinking Behavior in Male, Alcohol-Preferring Rats. JOURNAL OF NEUROSCIENCE RESEARCH. 93:930-937.Full Text via DOI: 10.1002/jnr.23554
-
2015Histomorphometric Analysis of Salivary Gland in Wistar Rats Treated Chronically With Two Benzodiazepines. CURRENT PHARMACEUTICAL BIOTECHNOLOGY. 16:573-578.
-
2015Monoamine Oxidase Inhibitors Extracted from Tobacco Smoke as Neuroprotective Factors for Potential Treatment of Parkinson's Disease. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. 14:777-785.
-
2015Histomorphometric Analysis of Salivary Gland in Wistar Rats Treated Chronically With Two Benzodiazepines. CURRENT PHARMACEUTICAL BIOTECHNOLOGY. 16:573-578.Full Text via DOI: 10.2174/138920101606150407115258
-
2015Monoamine Oxidase Inhibitors Extracted from Tobacco Smoke as Neuroprotective Factors for Potential Treatment of Parkinson’s Disease. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. 14:777-785.Full Text via DOI: 10.2174/1871527314666150325235608
-
2014Effects of MS-153 on chronic ethanol consumption and GLT1 modulation of glutamate levels in male alcohol-preferring rats. FRONTIERS IN BEHAVIORAL NEUROSCIENCE. 8.Full Text via DOI: 10.3389/fnbeh.2014.00366
-
2014Effects of ceftriaxone on ethanol intake: a possible role for xCT and GLT-1 isoforms modulation of glutamate levels in P rats. PSYCHOPHARMACOLOGY. 231:4049-4057.Full Text via DOI: 10.1007/s00213-014-3545-y
-
2014Effects of Ceftriaxone on Chronic Ethanol Consumption: a Potential Role for xCT and GLT1 Modulation of Glutamate Levels in Male P Rats. JOURNAL OF MOLECULAR NEUROSCIENCE. 54:71-77.Full Text via DOI: 10.1007/s12031-014-0251-5
-
2014Three Types of Ependymal Cells With Intracellular Calcium Oscillation Are Characterized by Distinct Cilia Beating Properties. JOURNAL OF NEUROSCIENCE RESEARCH. 92:1199-1204.Full Text via DOI: 10.1002/jnr.23405
-
2014Effects of Ceftriaxone on Systemic and Central Expression of Anti- and Pro-inflammatory Cytokines in Alcohol-Preferring (P) Rats Exposed to Ethanol. ALCOHOL AND ALCOHOLISM. 49:390-398.Full Text via DOI: 10.1093/alcalc/agu019
-
2014Potential Therapeutic Drugs and Methods for the Treatment of Amyotrophic Lateral Sclerosis. CURRENT MEDICINAL CHEMISTRY. 21:3583-3593.
-
2014Therapeutic Perspectives of Drugs Targeting Toll-Like Receptors Based on Immune Physiopathology Theory of Alzheimer's Disease. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. 13:909-920.
-
2014Potential Therapeutic Drugs and Methods for the Treatment of Amyotrophic Lateral Sclerosis. CURRENT MEDICINAL CHEMISTRY. 21:3583-3593.Full Text via DOI: 10.2174/0929867321666140601162710
-
2014Therapeutic Perspectives of Drugs Targeting Toll-Like Receptors Based on Immune Physiopathology Theory of Alzheimer’s Disease. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. 13:909-920.Full Text via DOI: 10.2174/1871527313666140711093858
-
2013Ceftriaxone Treatment Affects the Levels of GLT1 and ENT1 As Well As Ethanol Intake in Alcohol-Preferring Rats. JOURNAL OF MOLECULAR NEUROSCIENCE. 51:779-787.Full Text via DOI: 10.1007/s12031-013-0064-y
-
2013EFFECTS OF CEFTRIAXONE ON THE ACQUISITION AND MAINTENANCE OF ETHANOL DRINKING IN PERI-ADOLESCENT AND ADULT FEMALE ALCOHOL-PREFERRING (P) RATS. NEUROSCIENCE. 241:229-238.Full Text via DOI: 10.1016/j.neuroscience.2013.03.016
-
2013Ceftriaxone, a beta-lactam antibiotic, attenuates relapse-like ethanol-drinking behavior in alcohol-preferring rats. JOURNAL OF PSYCHOPHARMACOLOGY. 27:541-549.Full Text via DOI: 10.1177/0269881113482529
-
2013Experimental Methods for Testing the Effects of Neurotrophic Peptide, ADNF-9, Against Alcohol-induced Apoptosis during Pregnancy in C57BL/6 Mice. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS.Full Text via DOI: 10.3791/50092
-
2013Neurotrophic Peptides, ADNF-9 and NAP, Prevent Alcohol-Induced Apoptosis at Midgestation in Fetal Brains of C57BL/6 Mouse. JOURNAL OF MOLECULAR NEUROSCIENCE. 49:150-156.Full Text via DOI: 10.1007/s12031-012-9921-3
-
2012NEUROIMMUNOPHILIN GPI-1046 REDUCES ETHANOL CONSUMPTION IN PART THROUGH ACTIVATION OF GLT1 IN ALCOHOL-PREFERRING RATS. NEUROSCIENCE. 227:327-335.Full Text via DOI: 10.1016/j.neuroscience.2012.10.007
-
2012Cilostazol Prevents Endothelin-Induced Smooth Muscle Constriction and Proliferation. PLOS ONE. 7.Full Text via DOI: 10.1371/journal.pone.0044476
-
2011Neuroprotective peptide ADNF-9 in fetal brain of C57BL/6 mice exposed prenatally to alcohol. JOURNAL OF BIOMEDICAL SCIENCE. 18.Full Text via DOI: 10.1186/1423-0127-18-77
-
2011Ceftriaxone, a Beta-Lactam Antibiotic, Reduces Ethanol Consumption in Alcohol-Preferring Rats. ALCOHOL AND ALCOHOLISM. 46:239-246.Full Text via DOI: 10.1093/alcalc/agr023
-
2010Ceftriaxone-induced up-regulation of cortical and striatal GLT1 in the R6/2 model of Huntington's disease. JOURNAL OF BIOMEDICAL SCIENCE. 17.Full Text via DOI: 10.1186/1423-0127-17-62
-
2010Alteration of selective neurotransmitters in fetal brains of prenatally alcohol‐treated C57BL/6 mice: quantitative analysis using liquid chromatography/tandem mass spectrometry. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE. 28:263-269.Full Text via DOI: 10.1016/j.ijdevneu.2010.01.004
-
2010Differential expression of proteins in fetal brains of alcohol-treated prenatally C57BL/6 mice: A proteomic investigation. ELECTROPHORESIS. 31:483-496.Full Text via DOI: 10.1002/elps.200900385
-
2009A novel peptide, colivelin, prevents alcohol-induced apoptosis in fetal brain of C57BL/6 mice: signaling pathway investigations. NEUROSCIENCE. 164:1653-1664.Full Text via DOI: 10.1016/j.neuroscience.2009.09.049
-
2009Activity-dependent neuroprotective protein–derived peptide, NAP, preventing alcohol-induced apoptosis in fetal brain of C57BL/6 mouse. NEUROSCIENCE. 158:1426-1435.Full Text via DOI: 10.1016/j.neuroscience.2008.11.021
-
2009Upregulation of Glt1 Attenuates Cue-Induced Reinstatement of Cocaine-Seeking Behavior in Rats. JOURNAL OF NEUROSCIENCE. 29:9239-9243.Full Text via DOI: 10.1523/jneurosci.1746-09.2009
-
2006Effects of Chronic Alcohol and Repeated Deprivations on Dopamine D1 and D2 Receptor Levels in the Extended Amygdala of Inbred Alcohol-Preferring Rats. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 30:46-56.Full Text via DOI: 10.1111/j.1530-0277.2006.00010.x
-
2006Glutamate and dopamine synaptic terminals in extended amygdala after 14-week chronic alcohol drinking in inbred alcohol-preferring rats. Alcohol. 39:39-49.Full Text via DOI: 10.1016/j.alcohol.2006.06.013
-
2006Structural and Functional Modifications in Glutamateric Synapses Following Prolonged Ethanol Exposure. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 30:368-376.Full Text via DOI: 10.1111/j.1530-0277.2006.00041.x
-
2005Fetal Alcohol Exposure Reduces Serotonin Innervation and Compromises Development of the Forebrain Along the Serotonergic Pathway. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 29:141-149.Full Text via DOI: 10.1097/01.alc.0000150636.19677.6f
-
2004A Neuroprotective Peptide Antagonizes Fetal Alcohol Exposure-Compromised Brain Growth. JOURNAL OF MOLECULAR NEUROSCIENCE. 24:189-200.Full Text via DOI: 10.1385/jmn:24:2:189
-
2004Neurotransmitters and Substances of Abuse: Effects on Adult Neurogenesis. Current Neurovascular Research. 1:251-260.Full Text via DOI: 10.2174/1567202043362225
-
2004Prenatal Alcohol Exposure Causes Long-Term Serotonin Neuron Deficit in Mice. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 28:941-948.Full Text via DOI: 10.1097/01.alc.0000128228.08472.39
-
2004Selective serotonin reuptake inhibitor disrupts organization of thalamocortical somatosensory barrels during development. Developmental Brain Research. 150:151-161.Full Text via DOI: 10.1016/j.devbrainres.2003.02.001
-
2004Serotonin receptors: from protein to physiological function and behavior. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. 28:565-582.Full Text via DOI: 10.1016/j.neubiorev.2004.08.008
-
2003Moderate alcohol exposure compromises neural tube midline development in prenatal brain. Developmental Brain Research. 144:43-55.Full Text via DOI: 10.1016/s0165-3806(03)00158-5
-
2003Serotonin and its transporter on proliferation of fetal heart cells. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE. 21:417-424.Full Text via DOI: 10.1016/j.ijdevneu.2003.10.002
-
2002Deviations in brain early serotonergic development as a result of fetal alcohol exposure. Neurotoxicity Research. 4:337-342.Full Text via DOI: 10.1080/10298420290030532
-
2001Alcohol deters the outgrowth of serotonergic neurons at midgestation. JOURNAL OF BIOMEDICAL SCIENCE. 8:119-125.Full Text via DOI: 10.1007/bf02255980
-
2001Prenatal alcohol exposure retards the migration and development of serotonin neurons in fetal C57BL mice. Developmental Brain Research. 126:147-155.Full Text via DOI: 10.1016/s0165-3806(00)00144-9
-
2000Expression of serotonin transporter protein in developing rat brain. Developmental Brain Research. 119:33-45.Full Text via DOI: 10.1016/s0165-3806(99)00152-2
-
-
Book Chapter (Web of Science)
-
2021Role of Metabotropic Glutamate Receptors in Alcohol-Drinking Behaviors. Neuromethods. 297-311.Full Text via DOI: 10.1007/978-1-0716-1107-4_14
-
2019Alcohol and Central Glutamate Activity: What Goes Up Must Come Down?. 453-461.Full Text via DOI: 10.1016/b978-0-12-813125-1.00047-7
-
2019Memory Dysfunction Correlates with the Dysregulated Dopaminergic System in the Ventral Tegmental Area in Alzheimer’s Disease. Application of Biomedical Engineering in Neuroscience. 85-98.Full Text via DOI: 10.1007/978-981-13-7142-4_5
-
2016A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction. ANIMAL MODELS FOR MEDICATIONS SCREENING TO TREAT ADDICTION. 179-261.Full Text via DOI: 10.1016/bs.irn.2016.02.017
-
2011Role of the Serotonergic System in Alcohol Dependence: From Animal Models to Clinics. BRAIN AS A DRUG TARGET. 401-443.Full Text via DOI: 10.1016/B978-0-12-385506-0.00010-7
-
-
Editorial Material (Web of Science)
-
2017Commentary: Targeting NMDA Receptor and Serotonin Transporter for the Treatment of Comorbid Alcohol Dependence and Depression. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 275-278.Full Text via DOI: 10.1111/acer.13310
-
-
Meeting Abstract (Web of Science)
-
2021Induction of Inflammation in the Brain by Daily JUUL Aerosol Inhalation. FASEB JOURNAL. fasebj.2021.35.S1.04368.Full Text via DOI: 10.1096/fasebj.2021.35.s1.04368
-
2015Alterations of Glial Glutamate Transporters and Certain Neurotransmitters in Alcohol Withdrawal Syndrome Using Alcohol Preferring Rat Model. NEUROPSYCHOPHARMACOLOGY. S585-S585.
-
2015EAAT2 and xCT Regulate Alcohol Seeking Behaviors in Rodents. BIOLOGICAL PSYCHIATRY. 27S-27S.
-
2012ACTIVATION OF GLUTAMATE TRANSPORTER 1 IN CENTRAL REWARD BRAIN REGIONS RESULTS IN REDUCTION OF ETHANOL INTAKE IN ALCOHOL-PREFERRING RATS. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 99A-99A.
-
-
Review Article (Web of Science)
-
2020Overview of Therapeutic Drugs and Methods for the Treatment of Parkinson's Disease. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. 195-206.Full Text via DOI: 10.2174/1871527319666200525011110 PMID: 32448109
-
2018Role of glutamatergic system and mesocorticolimbic circuits in alcohol dependence. PROGRESS IN NEUROBIOLOGY. 32-49.Full Text via DOI: 10.1016/j.pneurobio.2018.10.001
-
2018A computerized exposure system for animal models to optimize nicotine delivery into the brain through inhalation of electronic cigarette vapors or cigarette smoke. SAUDI PHARMACEUTICAL JOURNAL. 622-628.Full Text via DOI: 10.1016/j.jsps.2018.02.031
-
2017Rat animal models for screening medications to treat alcohol use disorders. NEUROPHARMACOLOGY. 201-243.Full Text via DOI: 10.1016/j.neuropharm.2017.02.004
-
2017Metabotropic and ionotropic glutamate receptors as potential targets for the treatment of alcohol use disorder. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. 14-31.Full Text via DOI: 10.1016/j.neubiorev.2017.02.024
-
2016Targeting glutamate homeostasis for potential treatment of nicotine dependence. BRAIN RESEARCH BULLETIN. 1-8.Full Text via DOI: 10.1016/j.brainresbull.2015.11.010
-
2015Targeting glutamate uptake to treat alcohol use disorders. FRONTIERS IN NEUROSCIENCE.Full Text via DOI: 10.3389/fnins.2015.00144
-
2015The 5-HT7 receptor as a potential target for treating drug and alcohol abuse. FRONTIERS IN NEUROSCIENCE.Full Text via DOI: 10.3389/fnins.2014.00448
-
2013Role of 5-hydroxytryptamine 1B (5-HT1B) receptors in the regulation of ethanol intake in rodents. JOURNAL OF PSYCHOPHARMACOLOGY. 3-12.Full Text via DOI: 10.1177/0269881112463126
-
2012Glutamate Transporter 1: Target for the Treatment of Alcohol Dependence. CURRENT MEDICINAL CHEMISTRY. 5148-5156.
-
2012Adenosine and Glutamate Signaling in Neuron-Glial Interactions: Implications in Alcoholism and Sleep Disorders. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 1117-1125.Full Text via DOI: 10.1111/j.1530-0277.2011.01722.x
-
2012Glutamate Transporter 1: Target for the Treatment of Alcohol Dependence. CURRENT MEDICINAL CHEMISTRY. 5148-5156.Full Text via DOI: 10.2174/092986712803530511
-
2011Role of the Serotonergic System in Alcohol Dependence. 401-443.Full Text via DOI: 10.1016/b978-0-12-385506-0.00010-7
-
2006Brain deficits associated with fetal alcohol exposure may be protected, in part, by peptides derived from activity-dependent neurotrophic factor and activity-dependent neuroprotective protein. Brain Research Reviews. 107-118.Full Text via DOI: 10.1016/j.brainresrev.2006.01.004
-
Contact
full name
- Youssef Sari
visualizations
Cumulative publications in Scholars@UToledo