Neuroprotective peptide ADNF-9 in fetal brain of C57BL/6 mice exposed prenatally to alcohol Article (Faculty180)

cited authors

  • Sari, Youssef; Segu, Zaneer M; YoussefAgha, Ahmed; Karty, Jon A; Isailovic, Dragan

description

  • A derived peptide from activity-dependent neurotrophic factor (ADNF-9) has been shown to be neuroprotective in the fetal alcohol exposure model. We investigated the neuroprotective effects of ADNF-9 against alcohol-induced apoptosis using TUNEL staining. We further characterize in this study the proteomic architecture underlying the role of ADNF-9 against ethanol teratogenesis during early fetal brain development using liquid chromatography in conjunction with tandem mass spectrometry (LC-MS/MS).

authors

publication date

  • 2011

published in

start page

  • 77

volume

  • 18