Effects of ceftriaxone on GLT1 isoforms, xCT and associated signaling pathways in P rats exposed to ethanol Article (Faculty180)

cited authors

  • Rao, P S; Saternos, Hannah; Goodwani, Sunil; Sari, Youssef


  • Several studies have demonstrated a correlation between extracellular glutamate concentration in the mesolimbic reward pathway and alcohol craving. Extracellular glutamate concentration is regulated by several glutamate transporters. Glial glutamate transporter 1 (GLT1) is one of them that regulates the majority of extracellular glutamate concentration. In addition, cystine/glutamate antiporter (xCT) is another transporter that regulates extracellular glutamate.


publication date

  • 2015

published in

start page

  • 2333

end page

  • 42


  • 232