Activation of α7 nicotinic receptors attenuated hyperalgesia and anxiety induced by palatable obesogenic diet withdrawal Article (Faculty180)

cited authors

  • AlSharari, Shakir D; Alameen, Alaa A; Aldafiri, Fawzeyah S; Ali, Yousif S; Alshammari, Musaad A; Sari, Youssef; Damaj, M I

description

  • Consumption of palatable food (PF) can alleviate anxiety, and pain in humans. Contrary, spontaneous withdrawal of long-term PF intake produces anxiogenic-like behavior and abnormal pain sensation, causing challenges to weight-loss diet and anti-obesity agents. Thus, we examined α7-nicotinic acetylcholine receptors (α7nAChR) involvement since it plays essential role in nociception and psychological behaviors.

authors

publication date

  • 2024

published in

start page

  • 86

end page

  • 101

volume

  • 156