Koch, Lauren Gerard

Lauren Gerard Koch
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Positions

Associate Professor, Physiology and Pharmacology , College of Medicine and Life Sciences

Contact Info

Lauren.Koch2@utoledo.edu

https://www.utoledo.edu/med/depts/physpharm/

selected publications

Article (Faculty180)
- 2022
  
  Age and Intrinsic Fitness Affect the Female Rotator Cuff Tendon Tissue. Biomedicines. 10.
- 2022
  
  Altered skeletal muscle sarco-endoplasmic reticulum Ca-ATPase calcium transport efficiency after a thermogenic stimulus. American journal of physiology. Regulatory, integrative and comparative physiology. 323:R628-R637.
- 2022
  
  Biology: Motion is Function. Function (Oxford, England). 3:zqac030.
- 2022
  
  Effect of short-term hindlimb immobilization on skeletal muscle atrophy and the transcriptome in a low compared with high responder to endurance training model. PloS one. 17:e0261723.
- 2022
  
  Life-long exercise training and inherited aerobic endurance capacity produce converging gut microbiome signatures in rodents. Physiological reports. 10:e15215.
- 2022
  
  Rats with high aerobic capacity display enhanced transcriptional adaptability and upregulation of bile acid metabolism in response to an acute high-fat diet. Physiological reports. 10:e15405.
- 2021
  
  A collagen extraction and deuterium oxide stable isotope tracer method for the quantification of bone collagen synthesis rates in vivo. Physiological reports. 9:e14799.
- 2021
  
  Augmented Cardiac Mitochondrial Capacity in High Capacity Aerobic Running "Disease-Resistant" Phenotype at Rest Is Lost Following Ischemia Reperfusion. Frontiers in cardiovascular medicine. 8:752640.
- 2021
  
  Differential weight loss with intermittent fasting or daily calorie restriction in low- and high-fitness phenotypes. Experimental physiology. 106:1731-1742.
- 2021
  
  Enhanced weight and fat loss from long-term intermittent fasting in obesity-prone, low-fitness rats. Physiology & behavior. 230:113280.
- 2021
  
  Genetically determined exercise capacity affects systemic glucose response to insulin in rats. Physiological genomics. 53:395-405.
- 2021
  
  Hydrocephalus Following Experimental Subarachnoid Hemorrhage in Rats with Different Aerobic Capacity. International journal of molecular sciences. 22.
- 2021
  
  Influence of Intrinsic Aerobic Exercise Capacity and Sex on Cardiac Injury Following Acute Myocardial Ischemia and Reperfusion. Frontiers in cardiovascular medicine. 8:751864.
- 2021
  
  Interactive effects of aging and aerobic capacity on energy metabolism-related metabolites of serum, skeletal muscle, and white adipose tissue. GeroScience. 43:2679-2691.
- 2021
  
  Intrinsic Aerobic Capacity Affects Hippocampal pAkt and HSP72 Response to an Acute High Fat Diet and Heat Treatment in Rats. Journal of Alzheimer's disease reports. 5:469-475.
- 2021
  
  Low Intrinsic Aerobic Capacity Limits Recovery Response to Hindlimb Ischemia. Frontiers in cardiovascular medicine. 8:752955.
- 2021
  
  Low responders to endurance training exhibit impaired hypertrophy and divergent biological process responses in rat skeletal muscle. Experimental physiology. 106:714-725.
- 2021
  
  Mitochondrial health is enhanced in rats with higher vs. lower intrinsic exercise capacity and extended lifespan. NPJ aging and mechanisms of disease. 7:1.
- 2021
  
  Myokine Responses to Exercise in a Rat Model of Low/High Adaptive Potential. Frontiers in endocrinology. 12:645881.
- 2021
  
  Rat models for low and high adaptive response to exercise differ for stress-related memory and anxiety. Physiological reports. 9:e14716.
- 2021
  
  Rats bred for low intrinsic aerobic exercise capacity link obesity with brain inflammation and reduced structural plasticity of the hippocampus. Brain, behavior, and immunity. 97:250-259.
- 2021
  
  Rats with elevated genetic risk for metabolic syndrome exhibit cognitive deficiencies when young. Physiology & behavior. 236:113417.
- 2021
  
  SARS-CoV-2, ACE2 expression, and systemic organ invasion. Physiological genomics. 53:51-60.
- 2021
  
  Skeletal muscle heme oxygenase-1 activity regulates aerobic capacity. Cell reports. 35:109018.
- 2021
  
  The Effect of Age and Intrinsic Aerobic Exercise Capacity on the Expression of Inflammation and Remodeling Markers in Rat Achilles Tendons. International journal of molecular sciences. 23.
- 2020
  
  Aerobic capacity modulates adaptive thermogenesis: Contribution of non-resting energy expenditure. Physiology & behavior. 225:113048.
- 2020
  
  Aerobics - decades of data for future hypothesis-testing research. Nature reviews. Endocrinology. 16:627-628.
- 2020
  
  Comparative Analysis of Skeletal Muscle Transcriptional Signatures Associated With Aerobic Exercise Capacity or Response to Training in Humans and Rats. Frontiers in endocrinology. 11:591476.
- 2020
  
  Differences in intrinsic aerobic capacity alters sensitivity to ischemia-reperfusion injury but not cardioprotective capacity by ischemic preconditioning in rats. PloS one. 15:e0240866.
- 2020
  
  Hyperglycaemia is associated with impaired muscle signalling and aerobic adaptation to exercise. Nature metabolism. 2:902-917.
- 2020
  
  Insulin sensing by astrocytes is critical for normal thermogenesis and body temperature regulation. Journal of Endocrinology. 247:39.
- 2020
  
  Metabolites and Hypertension: Insights into Hypertension as a Metabolic Disorder: 2019 Harriet Dustan Award. Hypertension (Dallas, Tex. : 1979). 75:1386-1396.
- 2020
  
  Rats Genetically Selected for High Aerobic Exercise Capacity Have Elevated Plasma Bilirubin by Upregulation of Hepatic Biliverdin Reductase-A (BVRA) and Suppression of UGT1A1. Antioxidants (Basel, Switzerland). 9.
- 2020
  
  Rats genetically selected for low and high aerobic capacity exhibit altered soleus muscle myofilament functions. American journal of physiology. Cell physiology. 318:C422-C429.
- 2020
  
  Striated muscle-specific serine/threonine-protein kinase beta segregates with high versus low responsiveness to endurance exercise training. Physiological genomics. 52:35-46.
- 2019
  
  Beneficial effects of running and milk protein supplements on Sirtuins and risk factors of metabolic disorders in rats with low aerobic capacity. Metabolism open. 4:100019.
- 2019
  
  Denervation and senescence markers data from old rats with intrinsic differences in responsiveness to aerobic training. Data in brief. 27:104570.
- 2019
  
  Intrinsic High Aerobic Capacity in Male Rats Protects Against Diet-Induced Insulin Resistance. Endocrinology. 160:1179-1192.
- 2019
  
  Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training. Experimental gerontology. 125:110657.
- 2019
  
  Precision exercise medicine: understanding exercise response variability. British journal of sports medicine. 53:1141-1153.
- 2019
  
  Rat Models of Exercise for the Study of Complex Disease. Methods in molecular biology (Clifton, N.J.). 2018:309-317.
- 2018
  
  Are There Limitations to Exercise Benefits in Peripheral Arterial Disease?. Frontiers in cardiovascular medicine. 5:173.
- 2018
  
  Differential regulation of cysteine oxidative post-translational modifications in high and low aerobic capacity. Sci Rep.
- 2018
  
  Differential regulation of cysteine oxidative post-translational modifications in high and low aerobic capacity. Scientific reports. 8:17772.
- 2018
  
  Inherently Lean Rats Have Enhanced Activity and Skeletal Muscle Response to Central Melanocortin Receptors. Obesity (Silver Spring, Md.). 26:885-894.
- 2018
  
  Physiological adaptations to resistance training in rats selectively bred for low and high response to aerobic exercise training. Exp Physio.
- 2018
  
  Physiological adaptations to resistance training in rats selectively bred for low and high response to aerobic exercise training. Experimental physiology. 103:1513-1523.
- 2018
  
  Region-specific differences in bioenergetic proteins and protein response to acute high fat diet in brains of low and high capacity runner rats. Neuroscience letters. 674:49-53.
- 2018
  
  Skeletal muscle metabolism in rats with low and high intrinsic aerobic capacity: Effect of aging and exercise training. PloS one. 13:e0208703.
- 2018
  
  Skeletal muscle metabolism in rats with low and high intrinsic aerobic capacity: Effect of aging and exercise training. . PLoS One.
- 2018
  
  Soy protein improves tibial whole-bone and tissue-level biomechanical properties in ovariectomized and ovary-intact, low-fit female rats. Bone reports. 8:244-254.
- 2018
  
  Vertical sleeve gastrectomy corrects metabolic perturbations in a low-exercise capacity rat model. Molecular metabolism. 11:189-196.
- 2016
  
  Athlome Project Consortium: a concerted effort to discover genomic and other "omic" markers of athletic performance. Physiological genomics. 48:183-90.
- 2016
  
  Effect of Gender on Iron-induced Brain Injury in Low Aerobic Capacity Rats. Acta neurochirurgica. Supplement. 121:367-71.
- 2016
  
  Effects of Aerobic Capacity on Thrombin-Induced Hydrocephalus and White Matter Injury. Acta neurochirurgica. Supplement. 121:379-84.
- 2016
  
  Effects of ovariectomy and intrinsic aerobic capacity on tissue-specific insulin sensitivity. American journal of physiology. Endocrinology and metabolism. 310:E190-9.
- 2016
  
  Ovariectomized Highly Fit Rats Are Protected against Diet-Induced Insulin Resistance. Medicine and science in sports and exercise. 48:1259-69.
- 2016
  
  Physical exercise increases adult hippocampal neurogenesis in male rats provided it is aerobic and sustained. The Journal of physiology. 594:1855-73.
- 2016
  
  Rodent models for resolving extremes of exercise and health. Physiological genomics. 48:82-92.
- 2015
  
  Blunted cardiomyocyte remodeling response in exercise-resistant rats. Journal of the American College of Cardiology. 65:1378-1380.
- 2015
  
  Contribution of regional brain melanocortin receptor subtypes to elevated activity energy expenditure in lean, active rats. Neuroscience. 310:252-67.
- 2015
  
  Divergent role of nitric oxide in insulin-stimulated aortic vasorelaxation between low- and high-intrinsic aerobic capacity rats. Physiological reports. 3.
- 2015
  
  Exaggerated Acute Lung Injury and Impaired Antibacterial Defenses During Staphylococcus aureus Infection in Rats with the Metabolic Syndrome. PloS one. 10:e0126906.
- 2015
  
  Female rats selectively bred for high intrinsic aerobic fitness are protected from ovariectomy-associated metabolic dysfunction. American journal of physiology. Regulatory, integrative and comparative physiology. 308:R530-42.
- 2015
  
  High Intrinsic Aerobic Capacity Protects against Ethanol-Induced Hepatic Injury and Metabolic Dysfunction: Study Using High Capacity Runner Rat Model. Biomolecules. 5:3295-308.
- 2015
  
  High intrinsic aerobic capacity and pomegranate juice are protective against macrophage atherogenecity: studies in high- vs. low-capacity runner (HCR vs. LCR) rats. The Journal of nutritional biochemistry. 26:1015-21.
- 2015
  
  Iron-induced necrotic brain cell death in rats with different aerobic capacity. Translational stroke research. 6:215-23.
- 2015
  
  Label-free profiling of white adipose tissue of rats exhibiting high or low levels of intrinsic exercise capacity. Proteomics. 15:2342-9.
- 2015
  
  Maximal oxidative capacity during exercise is associated with skeletal muscle fuel selection and dynamic changes in mitochondrial protein acetylation. Cell metabolism. 21:468-78.
- 2015
  
  Mitochondrial biogenesis-associated factors underlie the magnitude of response to aerobic endurance training in rats. Pflugers Archiv : European journal of physiology. 467:779-88.
- 2015
  
  Ovariectomy results in differential shifts in gut microbiota in low versus high aerobic capacity rats. Physiological reports. 3.
- 2015
  
  Physical Activity Differentially Affects the Cecal Microbiota of Ovariectomized Female Rats Selectively Bred for High and Low Aerobic Capacity. PloS one. 10:e0136150.
- 2015
  
  Physical activity in adulthood: genes and mortality. Scientific reports. 5:18259.
- 2015
  
  Physically active rats lose more weight during calorie restriction. Physiology & behavior. 139:303-13.
- 2015
  
  Role of intrinsic aerobic capacity and ventilator-induced diaphragm dysfunction. Journal of applied physiology (Bethesda, Md. : 1985). 118:849-57.
- 2014
  
  Brain diabetic neurodegeneration segregates with low intrinsic aerobic capacity. Annals of clinical and translational neurology. 1:589-604.
- 2014
  
  Conditional independence mapping of DIGE data reveals PDIA3 protein species as key nodes associated with muscle aerobic capacity. Journal of proteomics. 106:230-45.
- 2014
  
  Eszopiclone and dexmedetomidine depress ventilation in obese rats with features of metabolic syndrome. Sleep. 37:871-80.
- 2014
  
  Exercise Increases Markers of Spermatogenesis in Rats Selectively Bred for Low Running Capacity. PloS one. 9:e114075.
- 2014
  
  Intrinsic aerobic capacity impacts susceptibility to acute high-fat diet-induced hepatic steatosis. American journal of physiology. Endocrinology and metabolism. 307:E355-64.
- 2014
  
  Label-free profiling of skeletal muscle using high-definition mass spectrometry. Proteomics. 14:2339-44.
- 2014
  
  Leanness and heightened nonresting energy expenditure: role of skeletal muscle activity thermogenesis. American journal of physiology. Endocrinology and metabolism. 306:E635-47.
- 2014
  
  Reduced aerobic capacity causes leaky ryanodine receptors that trigger arrhythmia in a rat strain artificially selected and bred for low aerobic running capacity. Acta physiologica (Oxford, England). 210:854-64.
- 2014
  
  Resveratrol attenuates exercise-induced adaptive responses in rats selectively bred for low running performance. Dose-response : a publication of International Hormesis Society. 12:57-71.
- 2014
  
  Striatal enkephalinergic differences in rats selectively bred for intrinsic running capacity. Brain research. 1572:11-7.
- 2013
  
  (-)-Epicatechin is associated with increased angiogenic and mitochondrial signalling in the hindlimb of rats selectively bred for innate low running capacity. Clinical science (London, England : 1979). 124:663-74.
- 2013
  
  Aerobic endurance capacity affects spatial memory and SIRT1 is a potent modulator of 8-oxoguanine repair. Neuroscience. 252:326-36.
- 2013
  
  Atrial myocyte function and Ca2+ handling is associated with inborn aerobic capacity. PloS one. 8:e76568.
- 2013
  
  Dysfunction of inflammation-resolving pathways is associated with exaggerated postoperative cognitive decline in a rat model of the metabolic syndrome. Molecular medicine (Cambridge, Mass.). 18:1481-90.
- 2013
  
  Enhanced cardiac protein glycosylation (O-GlcNAc) of selected mitochondrial proteins in rats artificially selected for low running capacity. Physiological genomics. 45:17-25.
- 2013
  
  Exercise training enhances white adipose tissue metabolism in rats selectively bred for low- or high-endurance running capacity. American journal of physiology. Endocrinology and metabolism. 305:E429-38.
- 2013
  
  Genetic analysis of a rat model of aerobic capacity and metabolic fitness. PloS one. 8:e77588.
- 2013
  
  High inborn aerobic capacity does not protect the heart following myocardial infarction. Journal of applied physiology (Bethesda, Md. : 1985). 115:1788-95.
- 2013
  
  Label-Free LC-MS Profiling of Skeletal Muscle Reveals Heart-Type Fatty Acid Binding Protein as a Candidate Biomarker of Aerobic Capacity. Proteomes. 1:290-308.
- 2013
  
  Low intrinsic exercise capacity in rats predisposes to age-dependent cardiac remodeling independent of macrovascular function. American journal of physiology. Heart and circulatory physiology. 304:H729-39.
- 2013
  
  Rats selectively bred for differences in aerobic capacity have similar hypertensive responses to chronic intermittent hypoxia. American journal of physiology. Heart and circulatory physiology. 305:H403-9.
- 2013
  
  Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks. Diabetes. 62:2717-27.
- 2013
  
  Resveratrol enhances exercise training responses in rats selectively bred for high running performance. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 61:53-9.
- 2013
  
  Selectively bred rat model system for low and high response to exercise training. Physiological genomics. 45:606-14.
- 2013
  
  Surgery results in exaggerated and persistent cognitive decline in a rat model of the Metabolic Syndrome. Anesthesiology. 118:1098-105.
- 2013
  
  Susceptibility to intracerebral hemorrhage-induced brain injury segregates with low aerobic capacity in rats. Neurobiology of disease. 49:22-8.
- 2013
  
  Total synthesis and structural revision of viridicatumtoxin B. Angewandte Chemie (International ed. in English). 52:8736-41.
- 2013
  
  Uphill running does not exacerbate collagenase-induced pathological changes in the Achilles tendon of rats selectively bred for high-capacity running. Connective tissue research. 54:386-93.
- 2013
  
  Uphill treadmill running does not induce histopathological changes in the rat Achilles tendon. BMC musculoskeletal disorders. 14:90.
- 2013
  
  Vascularity of myocardium and gastrocnemius muscle in rats selectively bred for endurance running capacity. Physiological genomics. 45:119-25.
- 2012
  
  A rat model system to study complex disease risks, fitness, aging, and longevity. Trends in cardiovascular medicine. 22:29-34.
- 2012
  
  Brain activation patterns at exhaustion in rats that differ in inherent exercise capacity. PloS one. 7:e45415.
- 2012
  
  Determination of minimum alveolar concentration for isoflurane and sevoflurane in a rodent model of human metabolic syndrome. Anesthesia and analgesia. 114:297-302.
- 2012
  
  Divergent skeletal muscle respiratory capacities in rats artificially selected for high and low running ability: a role for Nor1?. Journal of applied physiology (Bethesda, Md. : 1985). 113:1403-12.
- 2012
  
  Intrinsic aerobic capacity correlates with greater inherent mitochondrial oxidative and H2O2 emission capacities without major shifts in myosin heavy chain isoform. Journal of applied physiology (Bethesda, Md. : 1985). 113:1624-34.
- 2012
  
  Overweight female rats selectively breed for low aerobic capacity exhibit increased myocardial fibrosis and diastolic dysfunction. American journal of physiology. Heart and circulatory physiology. 302:H1667-82.
- 2012
  
  Rats bred for low aerobic capacity become promptly fatigued and have slow metabolic recovery after stimulated, maximal muscle contractions. PloS one. 7:e48345.
- 2012
  
  Region-specific differences in brain melanocortin receptors in rats of the lean phenotype. Neuroreport. 23:596-600.
- 2012
  
  Selective breeding for endurance running capacity affects cognitive but not motor learning in rats. Physiology & behavior. 106:95-100.
- 2011
  
  A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype. Journal of applied physiology (Bethesda, Md. : 1985). 110:46-59.
- 2011
  
  Changes in mRNA levels for brain-derived neurotrophic factor after wheel running in rats selectively bred for high- and low-aerobic capacity. Brain research. 1425:90-7.
- 2011
  
  Exercise training reverses impaired skeletal muscle metabolism induced by artificial selection for low aerobic capacity. American journal of physiology. Regulatory, integrative and comparative physiology. 300:R175-82.
- 2011
  
  Intrinsic aerobic capacity sets a divide for aging and longevity. Circulation research. 109:1162-72.
- 2011
  
  Low intrinsic running capacity is associated with reduced skeletal muscle substrate oxidation and lower mitochondrial content in white skeletal muscle. American journal of physiology. Regulatory, integrative and comparative physiology. 300:R835-43.
- 2011
  
  Lower oxidative DNA damage despite greater ROS production in muscles from rats selectively bred for high running capacity. American journal of physiology. Regulatory, integrative and comparative physiology. 300:R544-53.
- 2011
  
  Osteoblast response to ovariectomy is enhanced in intrinsically high aerobic-capacity rats. Calcified tissue international. 88:325-35.
- 2011
  
  Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity. Proteomics. 11:3369-79.
- 2011
  
  The effect of exercise training on transverse tubules in normal, remodeled, and reverse remodeled hearts. Journal of cellular physiology. 226:2235-43.
- 2010
  
  Caloric restriction reverses hepatic insulin resistance and steatosis in rats with low aerobic capacity. Endocrinology. 151:5157-64.
- 2010
  
  Dietary n-3:n-6 fatty acid ratios differentially influence hormonal signature in a rodent model of metabolic syndrome relative to healthy controls. Nutrition & metabolism. 7:53.
- 2010
  
  Disrupted sleep and delayed recovery from chronic peripheral neuropathy are distinct phenotypes in a rat model of metabolic syndrome. Anesthesiology. 113:1176-85.
- 2010
  
  Gene expression centroids that link with low intrinsic aerobic exercise capacity and complex disease risk. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24:4565-74.
- 2010
  
  Locus coeruleus galanin expression is enhanced after exercise in rats selectively bred for high capacity for aerobic activity. Peptides. 31:2264-8.
- 2010
  
  Low intrinsic aerobic exercise capacity and systemic insulin resistance are not associated with changes in myocardial substrate oxidation or insulin sensitivity. Basic research in cardiology. 105:357-64.
- 2010
  
  Phenotypic and evolutionary plasticity of body composition in rats selectively bred for high endurance capacity. Journal of applied physiology (Bethesda, Md. : 1985). 109:778-85.
- 2010
  
  Selection for intrinsic endurance modifies endocrine stress responsiveness. Brain research. 1357:53-61.
- 2010
  
  Skeletal muscle mitochondrial and metabolic responses to a high-fat diet in female rats bred for high and low aerobic capacity. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 35:151-62.
- 2010
  
  Spontaneous activity, economy of activity, and resistance to diet-induced obesity in rats bred for high intrinsic aerobic capacity. Hormones and behavior. 58:355-67.
- 2010
  
  Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. Journal of applied physiology (Bethesda, Md. : 1985). 108:1487-96.
- 2009
  
  Aerobic interval training vs. continuous moderate exercise in the metabolic syndrome of rats artificially selected for low aerobic capacity. Cardiovascular research. 81:723-32.
- 2009
  
  Artificial selection for whole animal low intrinsic aerobic capacity co-segregates with hypoxia-induced cardiac pump failure. PloS one. 4:e6117.
- 2009
  
  Continued artificial selection for running endurance in rats is associated with improved lung function. Journal of applied physiology (Bethesda, Md. : 1985). 106:1810-8.
- 2009
  
  Endurance capacity, not body size, determines physical activity levels: role of skeletal muscle PEPCK. PloS one. 4:e5869.
- 2009
  
  High-fat diet induces Ikkbeta and reduces insulin sensitivity in rats with low running capacity. International journal of sports medicine. 30:631-5.
- 2009
  
  Impaired skeletal muscle beta-adrenergic activation and lipolysis are associated with whole-body insulin resistance in rats bred for low intrinsic exercise capacity. Endocrinology. 150:4883-91.
- 2009
  
  Low aerobic capacity and high-fat diet contribute to oxidative stress and IRS-1 degradation in the kidney. American journal of nephrology. 30:112-9.
- 2009
  
  Peripheral oxygen transport and utilization in rats following continued selective breeding for endurance running capacity. Journal of applied physiology (Bethesda, Md. : 1985). 106:1819-25.
- 2009
  
  Rat strains bred for low and high aerobic running capacity do not differ in their survival time to hemorrhage. Experimental biology and medicine (Maywood, N.J.). 234:1503-10.
- 2009
  
  Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury. The Journal of physiology. 587:1805-16.
- 2008
  
  Aerobic capacity-dependent differences in cardiac gene expression. Physiological genomics. 33:100-9.
- 2008
  
  Aerobic metabolism underlies complexity and capacity. The Journal of physiology. 586:83-95.
- 2008
  
  Body mass index measures in children with cerebral palsy related to gross motor function classification: a clinic-based study. American journal of physical medicine & rehabilitation. 87:395-403.
- 2008
  
  Development of animal models to test the fundamental basis of gene-environment interactions. Obesity (Silver Spring, Md.). 16 Suppl 3:S28-32.
- 2008
  
  Gene expression profiling of skeletal muscle in exercise-trained and sedentary rats with inborn high and low VO2max. Physiological genomics. 35:213-21.
- 2008
  
  Initial signaling response to acute exercise bout is similar in hearts of rats bred for divergent exercise capacities. Frontiers in bioscience : a journal and virtual library. 13:347-55.
- 2008
  
  Nociception before and after exercise in rats bred for high and low aerobic capacity. Neuroscience letters. 443:37-40.
- 2008
  
  Selection for aerobic capacity affects corticosterone, monoamines and wheel-running activity. Physiology & behavior. 93:1044-54.
- 2007
  
  Artificial selection for high-capacity endurance running is protective against high-fat diet-induced insulin resistance. American journal of physiology. Endocrinology and metabolism. 293:E31-41.
- 2007
  
  Dysregulation of muscle lipid metabolism in rats selectively bred for low aerobic running capacity. American journal of physiology. Endocrinology and metabolism. 292:E1631-6.
- 2007
  
  Evolution, atmospheric oxygen, and complex disease. Physiological genomics. 30:205-8.
- 2007
  
  Nitric oxide synthase type-1 modulates cardiomyocyte contractility and calcium handling: association with low intrinsic aerobic capacity. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology. 14:319-25.
- 2007
  
  Upregulation of GAD65 mRNA in the medulla of the rat model of metabolic syndrome. Neuroscience letters. 419:178-83.
- 2006
  
  Aerobic capacity, oxidant stress, and chronic obstructive pulmonary disease--a new take on an old hypothesis. Pharmacology & therapeutics. 110:71-82.
- 2006
  
  Continued divergence in VO2max of rats artificially selected for running endurance is mediated by greater convective blood O2 delivery. Journal of applied physiology (Bethesda, Md. : 1985). 101:1288-96.
- 2006
  
  Elevated central monoamine receptor mRNA in rats bred for high endurance capacity: implications for central fatigue. Behavioural brain research. 174:132-42.
- 2006
  
  Enhanced mitochondrial sensitivity to creatine in rats bred for high aerobic capacity. Journal of applied physiology (Bethesda, Md. : 1985). 100:1765-9.
- 2006
  
  Reduced susceptibility to ventricular tachyarrhythmias in rats selectively bred for high aerobic capacity. American journal of physiology. Heart and circulatory physiology. 291:H2933-41.
- 2006
  
  Systemic oxygen transport in rats artificially selected for running endurance. Respiratory physiology & neurobiology. 151:141-50.
- 2005
  
  Animal models of complex diseases: an initial strategy. IUBMB life. 57:631-8.
- 2005
  
  Cardiac rehabilitation after heart transplantation in a patient with Becker's muscular dystrophy: a case report. Archives of physical medicine and rehabilitation. 86:2059-61.
- 2005
  
  Cardiovascular risk factors emerge after artificial selection for low aerobic capacity. Science (New York, N.Y.). 307:418-20.
- 2005
  
  Divergent selection for aerobic capacity in rats as a model for complex disease. Integrative and comparative biology. 45:405-15.
- 2003
  
  Genetic component of sensorimotor capacity in rats. Physiological genomics. 13:241-7.
- 2003
  
  Selected contribution: Variation and heritability for the adaptational response to exercise in genetically heterogeneous rats. Journal of applied physiology (Bethesda, Md. : 1985). 94:1674-81.
- 2003
  
  Selected contribution: skeletal muscle capillarity and enzyme activity in rats selectively bred for running endurance. Journal of applied physiology (Bethesda, Md. : 1985). 94:1682-8.
- 2002
  
  Cardiac adenosine production in rat genetic models of low and high exercise capacity. American journal of physiology. Regulatory, integrative and comparative physiology. 283:R168-73.
- 2002
  
  Determinants of maximal O(2) uptake in rats selectively bred for endurance running capacity. Journal of applied physiology (Bethesda, Md. : 1985). 93:1265-74.
- 2002
  
  Genetic Models of Aerobic Endurance Running Capacity in Rats. TheScientificWorldJournal. 2:13-14.
- 2001
  
  Animal genetic models for complex traits of physical capacity. Exercise and sport sciences reviews. 29:7-14.
- 2001
  
  Artificial selection for intrinsic aerobic endurance running capacity in rats. Physiological genomics. 5:45-52.
- 2001
  
  Cardiac function in rats selectively bred for low- and high-capacity running. American journal of physiology. Regulatory, integrative and comparative physiology. 281:R1787-91.
- 2001
  
  Cardiac performance in inbred rat genetic models of low and high running capacity. The Journal of physiology. 535:611-7.
- 2000
  
  State-dependent expression of pressure diuresis in conscious rats. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 224:109-15.
- 1999
  
  A gravimetric method for the measurement of total spontaneous activity in rats. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 222:65-9.
- 1999
  
  Phenotypic differences in cardiovascular regulation in inbred rat models of aerobic capacity. Physiological genomics. 1:63-9.
- 1999
  
  Phenotypic variation in sensorimotor performance among eleven inbred rat strains. The American journal of physiology. 276:R1383-9.
- 1998
  
  Heritability of treadmill running endurance in rats. The American journal of physiology. 275:R1455-60.
- 1998
  
  Phenotypic variation in strength among eleven inbred strains of rats. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 219:126-31.
- 1998
  
  Spectrum of aerobic endurance running performance in eleven inbred strains of rats. Journal of applied physiology (Bethesda, Md. : 1985). 85:530-6.
- 1994
  
  In vivo effect of naftidrofuryl on 5-hydroxytryptamine-mediated constriction in rat peripheral microcirculation. European journal of pharmacology. 254:249-55.
- 1991
  
  Reflex versus autoregulatory control of hindlimb blood flow during treadmill exercise in dogs. The American journal of physiology. 260:H436-44.
- 1990
  
  Adenosine is not essential for exercise hyperaemia in the hindlimb in conscious dogs. The Journal of physiology. 429:63-75.
Article (Web of Science)
- 2022
  
  Age and Intrinsic Fitness Affect the Female Rotator Cuff Tendon Tissue. BIOMEDICINES. 10.
  Full Text via DOI: 10.3390/biomedicines10020509 PMID: 35203717
- 2022
  
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  Exercise training reverses impaired skeletal muscle metabolism induced by artificial selection for low aerobic capacity. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 300:R175-R182.
  Full Text via DOI: 10.1152/ajpregu.00338.2010
- 2011
  
  Intrinsic Aerobic Capacity Sets a Divide for Aging and Longevity. CIRCULATION RESEARCH. 109:1162-1172.
  Full Text via DOI: 10.1161/circresaha.111.253807
- 2011
  
  Low intrinsic running capacity is associated with reduced skeletal muscle substrate oxidation and lower mitochondrial content in white skeletal muscle. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 300:R835-R843.
  Full Text via DOI: 10.1152/ajpregu.00659.2010
- 2011
  
  Lower oxidative DNA damage despite greater ROS production in muscles from rats selectively bred for high running capacity. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 300:R544-R553.
  Full Text via DOI: 10.1152/ajpregu.00250.2010
- 2011
  
  Osteoblast Response to Ovariectomy Is Enhanced in Intrinsically High Aerobic-Capacity Rats. CALCIFIED TISSUE INTERNATIONAL. 88:325-335.
  Full Text via DOI: 10.1007/s00223-010-9457-x
- 2011
  
  Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity. PROTEOMICS. 11:3369-3379.
  Full Text via DOI: 10.1002/pmic.201000593
- 2011
  
  Risk-assessment and Coping Strategies Segregate with Divergent Intrinsic Aerobic Capacity in Rats. NEUROPSYCHOPHARMACOLOGY. 36:390-401.
  Full Text via DOI: 10.1038/npp.2010.144
- 2011
  
  The effect of exercise training on transverse tubules in normal, remodeled, and reverse remodeled hearts. JOURNAL OF CELLULAR PHYSIOLOGY. 226:2235-2243.
  Full Text via DOI: 10.1002/jcp.22559
- 2010
  
  Caloric Restriction Reverses Hepatic Insulin Resistance and Steatosis in Rats with Low Aerobic Capacity. ENDOCRINOLOGY. 151:5157-5164.
  Full Text via DOI: 10.1210/en.2010-0176
- 2010
  
  Dietary n-3:n-6 fatty acid ratios differentially influence hormonal signature in a rodent model of metabolic syndrome relative to healthy controls. Nutrition & Metabolism. 7:53.
  Full Text via DOI: 10.1186/1743-7075-7-53
- 2010
  
  Disrupted Sleep and Delayed Recovery from Chronic Peripheral Neuropathy Are Distinct Phenotypes in a Rat Model of Metabolic Syndrome. ANESTHESIOLOGY. 113:1176-1185.
  Full Text via DOI: 10.1097/aln.0b013e3181f56248
- 2010
  
  Gene expression centroids that link with low intrinsic aerobic exercise capacity and complex disease risk. FASEB JOURNAL. 24:4565-4574.
  Full Text via DOI: 10.1096/fj.10-157313
- 2010
  
  Locus coeruleus galanin expression is enhanced after exercise in rats selectively bred for high capacity for aerobic activity. Peptides. 31:2264-2268.
  Full Text via DOI: 10.1016/j.peptides.2010.09.005
- 2010
  
  Low intrinsic aerobic exercise capacity and systemic insulin resistance are not associated with changes in myocardial substrate oxidation or insulin sensitivity. Basic Research in Cardiology. 105:357-364.
  Full Text via DOI: 10.1007/s00395-010-0087-2
- 2010
  
  Phenotypic and evolutionary plasticity of body composition in rats selectively bred for high endurance capacity. JOURNAL OF APPLIED PHYSIOLOGY. 109:778-785.
  Full Text via DOI: 10.1152/japplphysiol.01026.2009
- 2010
  
  Selection for intrinsic endurance modifies endocrine stress responsiveness. BRAIN RESEARCH. 1357:53-61.
  Full Text via DOI: 10.1016/j.brainres.2010.07.078
- 2010
  
  Skeletal muscle mitochondrial and metabolic responses to a high-fat diet in female rats bred for high and low aerobic capacity. APPLIED PHYSIOLOGY NUTRITION AND METABOLISM. 35:151-162.
  Full Text via DOI: 10.1139/h09-139
- 2010
  
  Spontaneous activity, economy of activity, and resistance to diet-induced obesity in rats bred for high intrinsic aerobic capacity. Hormones and Behavior. 58:355-367.
  Full Text via DOI: 10.1016/j.yhbeh.2010.03.013
- 2010
  
  Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. JOURNAL OF APPLIED PHYSIOLOGY. 108:1487-1496.
  Full Text via DOI: 10.1152/japplphysiol.01295.2009
- 2009
  
  Artificial Selection for Whole Animal Low Intrinsic Aerobic Capacity Co-Segregates with Hypoxia-Induced Cardiac Pump Failure. PLOS ONE. 4:e6117.
  Full Text via DOI: 10.1371/journal.pone.0006117
- 2009
  
  Continued artificial selection for running endurance in rats is associated with improved lung function. JOURNAL OF APPLIED PHYSIOLOGY. 106:1810-1818.
  Full Text via DOI: 10.1152/japplphysiol.90419.2008
- 2009
  
  High-Fat Diet Induces IKKβ and Reduces Insulin Sensitivity in Rats with Low Running Capacity. INTERNATIONAL JOURNAL OF SPORTS MEDICINE. 30:631-635.
  Full Text via DOI: 10.1055/s-0029-1224174
- 2009
  
  Impaired Skeletal Muscle β-Adrenergic Activation and Lipolysis Are Associated with Whole-Body Insulin Resistance in Rats Bred for Low Intrinsic Exercise Capacity. ENDOCRINOLOGY. 150:4883-4891.
  Full Text via DOI: 10.1210/en.2009-0158
- 2009
  
  Low Aerobic Capacity and High-Fat Diet Contribute to Oxidative Stress and IRS-1 Degradation in the Kidney. AMERICAN JOURNAL OF NEPHROLOGY. 30:112-119.
  Full Text via DOI: 10.1159/000204362
- 2009
  
  Peripheral oxygen transport and utilization in rats following continued selective breeding for endurance running capacity. JOURNAL OF APPLIED PHYSIOLOGY. 106:1819-1825.
  Full Text via DOI: 10.1152/japplphysiol.00914.2007
- 2009
  
  Rat Strains Bred for Low and High Aerobic Running Capacity Do Not Differ in Their Survival Time to Hemorrhage. Experimental Biology and Medicine. 234:1503-1510.
  Full Text via DOI: 10.3181/0812-rm-355
- 2009
  
  Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury. JOURNAL OF PHYSIOLOGY-LONDON. 587:1805-1816.
  Full Text via DOI: 10.1113/jphysiol.2009.169060
- 2008
  
  Aerobic capacity-dependent differences in cardiac gene expression. PHYSIOLOGICAL GENOMICS. 33:100-109.
  Full Text via DOI: 10.1152/physiolgenomics.00269.2007 PMID: 18171719
- 2008
  
  Aerobic interval training vs. continuous moderate exercise in the metabolic syndrome of rats artificially selected for low aerobic capacity. CARDIOVASCULAR RESEARCH. 81:723-732.
  Full Text via DOI: 10.1093/cvr/cvn332
- 2008
  
  Body Mass Index Measures in Children with Cerebral Palsy Related to Gross Motor Function Classification. American Journal of Physical Medicine & Rehabilitation. 87:395-403.
  Full Text via DOI: 10.1097/phm.0b013e3181617736
- 2008
  
  Development of Animal Models to Test the Fundamental Basis of Gene-Environment Interactions. OBESITY. 16:S28-S32.
  Full Text via DOI: 10.1038/oby.2008.513
- 2008
  
  Gene expression profiling of skeletal muscle in exercise-trained and sedentary rats with inborn high and low VO_2max. PHYSIOLOGICAL GENOMICS. 35:213-221.
  Full Text via DOI: 10.1152/physiolgenomics.90282.2008
- 2008
  
  Initial signaling response to acute exercise bout is similar in hearts of rats bred for divergent exercise capacities. FRONTIERS IN BIOSCIENCE-LANDMARK. 13:347.
  Full Text via DOI: 10.2741/2684
- 2008
  
  Nociception before and after exercise in rats bred for high and low aerobic capacity. NEUROSCIENCE LETTERS. 443:37-40.
  Full Text via DOI: 10.1016/j.neulet.2008.07.040
- 2008
  
  Selection for aerobic capacity affects corticosterone, monoamines and wheel-running activity. PHYSIOLOGY & BEHAVIOR. 93:1044-1054.
  Full Text via DOI: 10.1016/j.physbeh.2008.01.013
- 2007
  
  Congenic strains confirm aerobic running capacity quantitative trait loci on rat chromosome 16 and identify possible intermediate phenotypes. PHYSIOLOGICAL GENOMICS. 29:91-97.
  Full Text via DOI: 10.1152/physiolgenomics.00027.2006
- 2007
  
  Artificial selection for high-capacity endurance running is protective against high-fat diet-induced insulin resistance. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 293:E31-E41.
  Full Text via DOI: 10.1152/ajpendo.00500.2006
- 2007
  
  Evolution, atmospheric oxygen, and complex disease. PHYSIOLOGICAL GENOMICS. 30:205-208.
  Full Text via DOI: 10.1152/physiolgenomics.00043.2007
- 2007
  
  Nitric oxide synthase type-1 modulates cardiomyocyte contractility and calcium handling: association with low intrinsic aerobic capacity. European Journal of Cardiovascular Prevention & Rehabilitation. 14:319-325.
  Full Text via DOI: 10.1097/01.hjr.0b013e3280128bef
- 2007
  
  Upregulation of GAD65 mRNA in the medulla of the rat model of metabolic syndrome. NEUROSCIENCE LETTERS. 419:178-183.
  Full Text via DOI: 10.1016/j.neulet.2007.04.042
- 2006
  
  Continued divergence in V̇o_{2 max}of rats artificially selected for running endurance is mediated by greater convective blood O₂delivery. JOURNAL OF APPLIED PHYSIOLOGY. 101:1288-1296.
  Full Text via DOI: 10.1152/japplphysiol.01527.2005
- 2006
  
  Elevated central monoamine receptor mRNA in rats bred for high endurance capacity: Implications for central fatigue. BEHAVIOURAL BRAIN RESEARCH. 174:132-142.
  Full Text via DOI: 10.1016/j.bbr.2006.07.018
- 2006
  
  Enhanced mitochondrial sensitivity to creatine in rats bred for high aerobic capacity. JOURNAL OF APPLIED PHYSIOLOGY. 100:1765-1769.
  Full Text via DOI: 10.1152/japplphysiol.01533.2005
- 2006
  
  Reduced susceptibility to ventricular tachyarrhythmias in rats selectively bred for high aerobic capacity. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 291:H2933-H2941.
  Full Text via DOI: 10.1152/ajpheart.00514.2006
- 2006
  
  Systemic oxygen transport in rats artificially selected for running endurance. RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY. 151:141-150.
  Full Text via DOI: 10.1016/j.resp.2005.09.012
- 2005
  
  Cardiac Rehabilitation After Heart Transplantation in a Patient With Becker’s Muscular Dystrophy: A Case Report. ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION. 86:2059-2061.
  Full Text via DOI: 10.1016/j.apmr.2005.03.036
- 2005
  
  Cardiovascular Risk Factors Emerge After Artificial Selection for Low Aerobic Capacity. SCIENCE. 307:418-420.
  Full Text via DOI: 10.1126/science.1108177
- 2005
  
  Divergent Selection for Aerobic Capacity in Rats as a Model for Complex Disease. INTEGRATIVE AND COMPARATIVE BIOLOGY. 45:405-415.
  Full Text via DOI: 10.1093/icb/45.3.405
- 2005
  
  Test of the principle of initial value in rat genetic models of exercise capacity. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 288:R466-R472.
  Full Text via DOI: 10.1152/ajpregu.00621.2004
- 2003
  
  Genetic component of sensorimotor capacity in rats. PHYSIOLOGICAL GENOMICS. 13:241-247.
  Full Text via DOI: 10.1152/physiolgenomics.00137.2002
- 2003
  
  Selected Contribution: Skeletal muscle capillarity and enzyme activity in rats selectively bred for running endurance. JOURNAL OF APPLIED PHYSIOLOGY. 94:1682-1688.
  Full Text via DOI: 10.1152/japplphysiol.00556.2002
- 2003
  
  Selected Contribution: Variation and heritability for the adaptational response to exercise in genetically heterogeneous rats. JOURNAL OF APPLIED PHYSIOLOGY. 94:1674-1681.
  Full Text via DOI: 10.1152/japplphysiol.00851.2002
- 2002
  
  A Genome Scan for Loci Associated with Aerobic Running Capacity in Rats. GENOMICS. 80:13-20.
  Full Text via DOI: 10.1006/geno.2002.6797
- 2002
  
  Cardiac adenosine production in rat genetic models of low and high exercise capacity. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 283:R168-R173.
  Full Text via DOI: 10.1152/ajpregu.00621.2001
- 2002
  
  Determinants of maximal O₂ uptake in rats selectively bred for endurance running capacity. JOURNAL OF APPLIED PHYSIOLOGY. 93:1265-1274.
  Full Text via DOI: 10.1152/japplphysiol.00809.2001
- 2002
  
  Myocardial function in rat genetic models of low and high aerobic running capacity. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 282:R721-R726.
  Full Text via DOI: 10.1152/ajpregu.00367.2001
- 2001
  
  Artificial selection for intrinsic aerobic endurance running capacity in rats. PHYSIOLOGICAL GENOMICS. 5:45-52.
  Full Text via DOI: 10.1152/physiolgenomics.2001.5.1.45
- 2001
  
  Cardiac function in rats selectively bred for low- and high-capacity running. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 281:R1787-R1791.
  Full Text via DOI: 10.1152/ajpregu.2001.281.6.r1787
- 2001
  
  Cardiac performance in inbred rat genetic models of low and high running capacity. JOURNAL OF PHYSIOLOGY-LONDON. 535:611-617.
  Full Text via DOI: 10.1111/j.1469-7793.2001.00611.x
- 2000
  
  State-Dependent Expression of Pressure Diuresis in Conscious Rats. Proceedings of the Society for Experimental Biology and Medicine. 224:109-115.
  Full Text via DOI: 10.1046/j.1525-1373.2000.22408.x
- 1999
  
  A Gravimetric Method for the Measurement of Total Spontaneous Activity in Rats. Proceedings of the Society for Experimental Biology and Medicine. 222:65-69.
  Full Text via DOI: 10.1111/j.1525-1373.1999.09996.x
- 1999
  
  Phenotypic differences in cardiovascular regulation in inbred rat models of aerobic capacity. PHYSIOLOGICAL GENOMICS. 1:63-69.
  Full Text via DOI: 10.1152/physiolgenomics.1999.1.2.63
- 1999
  
  Phenotypic variation in sensorimotor performance among eleven inbred rat strains. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 276:R1383-R1389.
  Full Text via DOI: 10.1152/ajpregu.1999.276.5.r1383
- 1998
  
  Heritability of treadmill running endurance in rats. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 275:R1455-R1460.
  Full Text via DOI: 10.1152/ajpregu.1998.275.5.r1455
- 1998
  
  Spectrum of aerobic endurance running performance in eleven inbred strains of rats. JOURNAL OF APPLIED PHYSIOLOGY. 85:530-536.
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- 1991
  
  Reflex versus autoregulatory control of hindlimb blood flow during treadmill exercise in dogs. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 260:H436-H444.
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- 1990
  
  Adenosine is not essential for exercise hyperaemia in the hindlimb in conscious dogs.. JOURNAL OF PHYSIOLOGY-LONDON. 429:63-75.
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Early Access (Web of Science)
- 2020
  
  Aerobics - decades of data for future hypothesis-testing research. NATURE REVIEWS ENDOCRINOLOGY.
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Letter (Web of Science)
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  Blunted Cardiomyocyte Remodeling Response in Exercise-Resistant Rats. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1378-1380.
  Full Text via DOI: 10.1016/j.jacc.2015.01.041
Meeting Abstract (Web of Science)
- 2020
  
  Augmented Cardiac Mitochondrial Capacity in High Aerobic Capacity "Disease Resistant" Phenotype at Rest is Lost Following Ischemia Reperfusion. FASEB JOURNAL.
  Full Text via DOI: 10.1096/fasebj.2020.34.s1.07256
- 2020
  
  Differential Receptor-Mediated Inducible Gene Expression in Post Infarction Cardiac Fibroblasts is Altered by Intrinsic Exercise Phenotype. FASEB JOURNAL.
  Full Text via DOI: 10.1096/fasebj.2020.34.s1.07392
- 2020
  
  Female Rats Artificially Selected for Low and High Intrinsic Aerobic Capacity Swap Inflammatory Cascade in Resistance Arteries: Mechanisms of Cyclooxygenase-Derived Prostanoids. FASEB JOURNAL.
  Full Text via DOI: 10.1096/fasebj.2020.34.s1.04222
- 2020
  
  Relative Profibrotic Gene Expression in Cardiac Fibroblasts from Low Aerobic Capacity Disease Prone Rats Following Ischemic Reperfusion. FASEB JOURNAL.
  Full Text via DOI: 10.1096/fasebj.2020.34.s1.07377
- 2020
  
  Abstract P058: Female Rats Artificially Selected For Low Vs. High Intrinsic Aerobic Capacity Display Divergent Mechanisms In Vascular Inflammation. HYPERTENSION.
  Full Text via DOI: 10.1161/hyp.76.suppl_1.p058
- 2020
  
  Abstract P247: Gut Microbiota From A Rat Model Of Metabolic Syndrome Lowers Fitness Of High Exercise Capacity Rats (HCR/ Tol ) By Impairing Energy Homeostasis And Increasing Blood Pressure. HYPERTENSION.
  Full Text via DOI: 10.1161/hyp.76.suppl_1.p247
- 2018
  
  High Intrinsic Aerobic Endurance Capacity Preserves Cardiomyocyte Quality Control, Mitochondrial Fitness and Lifespan. BIOPHYSICAL JOURNAL. 662a.
  Full Text via DOI: 10.1016/j.bpj.2017.11.3572
- 2016
  
  Eating habits modulate short term memory and epigenetical regulation of brain derived neurotrophic factor in hippocampus of low- and high running capacity rats. FREE RADICAL BIOLOGY AND MEDICINE. S34-S35.
  Full Text via DOI: 10.1016/j.freeradbiomed.2016.04.069
- 2016
  
  Effects Of Intrinsic Aerobic Capacity And Ovariectomy on Voluntary Wheel Running and Mid-brain Dopamine Signaling. MEDICINE & SCIENCE IN SPORTS & EXERCISE. 823.
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  Influence of Intrinsic Aerobic Exercise Capacity on Skeletal Health. MEDICINE & SCIENCE IN SPORTS & EXERCISE. 821.
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- 2006
  
  Tu-P7:77 Endurance training reduces disease risk factors in rats artificially selected for low aerobic capacity. Atherosclerosis Supplements. 202.
  Full Text via DOI: 10.1016/s1567-5688(06)80785-3
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  Genetically Selected High Capacity Runners Have Altered Serotonergic and Dopaminergic Receptor mRNA in the Brain. MEDICINE & SCIENCE IN SPORTS & EXERCISE. S133.
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- 2005
  
  IN VITRO TNF-α PRODUCTION IS INCREASED IN ENDO- TOXIN-STIMULATED AVEOLAR MACROPHAGES FROM HIGH VERSUS LOW AEROBIC CAPACITY RATS.. CRITICAL CARE MEDICINE. A149.
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Proceedings Paper (Web of Science)
- 2016
  
  Effect of Gender on Iron-induced Brain Injury in Low Aerobic Capacity Rats. Acta Neurochirurgica Supplement. 367-371.
  Full Text via DOI: 10.1007/978-3-319-18497-5_63
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  Effects of Aerobic Capacity on Thrombin-Induced Hydrocephalus and White Matter Injury. Acta Neurochirurgica Supplement. 379-384.
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Review Article (Web of Science)
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  SARS-CoV-2, ACE2 expression, and systemic organ invasion. PHYSIOLOGICAL GENOMICS. 51-60.
  Full Text via DOI: 10.1152/physiolgenomics.00087.2020 PMID: 33275540
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  Are There Limitations to Exercise Benefits in Peripheral Arterial Disease?. FRONTIERS IN CARDIOVASCULAR MEDICINE.
  Full Text via DOI: 10.3389/fcvm.2018.00173 PMID: 30538994
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  Rodent models for resolving extremes of exercise and health. PHYSIOLOGICAL GENOMICS. 82-92.
  Full Text via DOI: 10.1152/physiolgenomics.00077.2015
- 2008
  
  Aerobic metabolism underlies complexity and capacity. JOURNAL OF PHYSIOLOGY-LONDON. 83-95.
  Full Text via DOI: 10.1113/jphysiol.2007.144709
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  Aerobic capacity, oxidant stress, and chronic obstructive pulmonary disease—A new take on an old hypothesis. Pharmacology & Therapeutics. 71-82.
  Full Text via DOI: 10.1016/j.pharmthera.2005.09.006
- 2005
  
  Animal models of complex diseases: An initial strategy. IUBMB LIFE. 631-638.
  Full Text via DOI: 10.1080/15216540500251684

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Lauren Gerard Koch

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