Disrupted sleep and delayed recovery from chronic peripheral neuropathy are distinct phenotypes in a rat model of metabolic syndrome Article (Faculty180)

cited authors

  • Muncey, Aa R; Saulles, Adam R; Koch, Lauren G; Britton, Steven L; Baghdoyan, Helen A; Lydic, Ralph


  • Sleep apnea, hypertension, atherosclerosis, and obesity are features of metabolic syndrome associated with decreased restorative sleep and increased pain. These traits are relevant for anesthesiology because they confer increased risks of a negative anesthetic outcome. This study tested the one-tailed hypothesis that rats bred for low intrinsic aerobic capacity have enhanced nociception and disordered sleep.

publication date

  • 2010

published in

start page

  • 1176

end page

  • 85


  • 113