Ahtiainen, Juha P; Lensu, Sanna; Ruotsalainen, Ilona; Schumann, Moritz; Ihalainen, Johanna K; Fachada, Vasco; Mendias, Christopher L; Brook, Matthew S; Smith, Kenneth; Atherton, Philip J; Koch, Lauren G; Britton, Steven L; Kainulainen, Heikki
What is the central question of this study? Can phenotypic traits associated with low response to one mode of training be extrapolated to other exercise-inducible phenotypes? The present study investigated whether rats that are low responders to endurance training are also low responders to resistance training. What is the main finding and its importance? After resistance training, rats that are high responders to aerobic exercise training improved more in maximal strength compared with low-responder rats. However, the greater gain in strength in high-responder rats was not accompanied by muscle hypertrophy, suggesting that the responses observed could be mainly neural in origin.