Rujun Gong
Contact Info
Overview
overview
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Rujun Gong, MD, PhD, FASN is currently Professor of Medicine and Director of Kidney Research in the Division of Nephrology, Department of Medicine at the University of Toledo College of Medicine or Medical College of Ohio (MCO). Besides, he also holds joint professorship at the Department of Physiology and Pharmacology. Prior to his joining the University of Toledo College of Medicine in 2018, Dr. Gong had been Associate Professor of Medicine and the founding Director of Kidney Research at Brown University School of Medicine and Rhode Island Hospital in Providence, Rhode Island, USA. Dr. Gong completed the seven-year Medical Education Program (MD degree) at Nanjing University in Nanjing, China, and later earned his PhD degree in Renal Physiology there. The Research Institute of Nephrology at Nanjing University is the largest and premier clinical and investigative nephrology program in China. There, he received systemic and intensive residency training in internal medicine and renal fellowship training in both clinical and investigative nephrology. After that, he completed his postdoctoral research fellowship training at Brown University. In 2004, he was recruited to the Faculty of Medicine at Brown University and was later promoted to Assistant and Associate Professor there. Dr. Gong's research interests center on pathogenesis and novel therapies of glomerular diseases, in particular podocytopathies and nephrotic syndrome and glomerulopathies; and pathogenic mechanisms of renal fibrogenesis and inflammation. His other research interests include epistasis in common kidney diseases; immunopathogenesis of lupus nephritis; transplant immune tolerance; and mechanisms of acute and chronic kidney injury, repair and regeneration. His research has been well funded by the US National Institutes of Health, private foundations and industry, and has been very active and productive with book chapters, patents and over 90 scientific papers published in high impact journals, including Nature Reviews Nephrology, Journal of the American Society of Nephrology, Kidney International, Gut, Pediatrics, American Journal of Transplantation, American Journal of Kidney Disease,Journal of Biological Chemistry, Journal of Pathology, Arthritis & Rheumatology, American Journal of Pathology, etc. Dr. Gong was awarded the Young Investigator Award in 2011 by the Chinese American Society of Nephrology for his cutting-edge research on the fundamental role of GSK3 and melanocortinergic pathways in kidney disease. He is an elected Fellow of the American Society of Nephrology (FASN) and is the current Treasurer for the Chinese American Society of Nephrology. He has served as Editor-in-Chief or editorial board member for a number of nephrology and molecular biology journals, and act as study section member for a number of funding agencies, including the US National Institutes of Health, the US Department of Veterans Affair Merit Award, the UK Medical Research Council and the American Association for the Advancement of Science (AAAS).
Publications
selected publications
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Article (Faculty180)
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2019Brain natriuretic peptide mitigates TIMP2 induction and reinstates extracellular matrix catabolic activity GSK3β inhibition in glomerular podocytes exposed to a profibrogenic milieu. American journal of translational research. 11:964-973.
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2019Mineralocorticoid receptor: A hidden culprit for hemodialysis vascular access dysfunction. EBioMedicine. 39:621-627.
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2018Blocking Macrophage Migration Inhibitory Factor Protects Against Cisplatin-Induced Acute Kidney Injury in Mice. Molecular therapy : the journal of the American Society of Gene Therapy. 26:2523-2532.
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2018Ecdysone Elicits Chronic Renal Impairment via Mineralocorticoid-Like Pathogenic Activities. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 49:1633-1645.
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2016Activation of FXR protects against renal fibrosis via suppressing Smad3 expression. Scientific reports. 6:37234.
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2016Enhancer of Zeste Homolog 2 Inhibition Attenuates Renal Fibrosis by Maintaining Smad7 and Phosphatase and Tensin Homolog Expression. Journal of the American Society of Nephrology : JASN. 27:2092-108.
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2015Fine-tuning of NFκB by glycogen synthase kinase 3β directs the fate of glomerular podocytes upon injury. Kidney international. 87:1176-90.
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2015P2X7 receptor inhibition protects against ischemic acute kidney injury in mice. American journal of physiology. Cell physiology. 308:C463-72.
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2015Therapeutic targeting of aldosterone: a novel approach to the treatment of glomerular disease. Clinical science (London, England : 1979). 128:527-35.
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Article (Web of Science)
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2023Hematopoietic-specific melanocortin 1 receptor signaling protects against nephrotoxic serum nephritis and mediates the beneficial effect of melanocortin therapy. KIDNEY INTERNATIONAL. 103:331-342.Full Text via DOI: 10.1016/j.kint.2022.09.025
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2023Negative Modulation of B Cell Activation by Melanocortin 1 Receptor Signaling Protects against Membranous Nephropathy. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 34:467-481.Full Text via DOI: 10.1681/asn.2022050605
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2022Hemopexin accumulates in kidneys and worsens acute kidney injury by causing hemoglobin deposition and exacerbation of iron toxicity in proximal tubules. KIDNEY INTERNATIONAL. 102:1320-1330.Full Text via DOI: 10.1016/j.kint.2022.07.024 PMID: 36007598
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2022Pharmacological Melanocortin 5 Receptor Activation Attenuates Glomerular Injury and Proteinuria in Rats With Puromycin Aminonucleoside Nephrosis. FRONTIERS IN PHYSIOLOGY. 13.Full Text via DOI: 10.3389/fphys.2022.887641 PMID: 35721571
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2022Age-related GSK3β overexpression drives podocyte senescence and glomerular aging. Journal of Clinical Investigation. 132.Full Text via DOI: 10.1172/jci141848
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2021The ketone body beta-hydroxybutyrate mitigates the senescence response of glomerular podocytes to diabetic insults. KIDNEY INTERNATIONAL. 100:1037-1053.Full Text via DOI: 10.1016/j.kint.2021.06.031 PMID: 34246657
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2021Rationale and Design of Assessing the Effectiveness of Short-Term Low-Dose Lithium Therapy in Averting Cardiac Surgery-Associated Acute Kidney Injury: A Randomized, Double Blinded, Placebo Controlled Pilot Trial. FRONTIERS IN MEDICINE. 8.Full Text via DOI: 10.3389/fmed.2021.639402 PMID: 34195206
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2021Permissive effect of GSK3 beta on profibrogenic plasticity of renal tubular cells in progressive chronic kidney disease. CELL DEATH & DISEASE. 12.Full Text via DOI: 10.1038/s41419-021-03709-5 PMID: 33931588
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2021Microdose Lithium Protects against Pancreatic Islet Destruction and Renal Impairment in Streptozotocin-Elicited Diabetes. ANTIOXIDANTS. 10.Full Text via DOI: 10.3390/antiox10010138 PMID: 33478120
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2020RNA-binding proteins tristetraprolin and human antigen R are novel modulators of podocyte injury in diabetic kidney disease. CELL DEATH & DISEASE. 11.Full Text via DOI: 10.1038/s41419-020-2630-x PMID: 32487989
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2020Relapse of Nephrotic Syndrome after Adrenocorticotropic Hormone-Induced Remission: Implications of Adrenocorticotropic Hormone Antibodies. AMERICAN JOURNAL OF NEPHROLOGY. 51:390-394.Full Text via DOI: 10.1159/000506854 PMID: 32187600
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2020Glycogen synthase kinase 3 beta hyperactivity in urinary exfoliated cells predicts progression of diabetic kidney disease. KIDNEY INTERNATIONAL. 97:175-192.Full Text via DOI: 10.1016/j.kint.2019.08.036 PMID: 31791666
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2020Melanocortin therapy ameliorates podocytopathy and proteinuria in experimental focal segmental glomerulosclerosis involving a podocyte specific non-MC1R-mediated melanocortinergic signaling. CLINICAL SCIENCE. 134:695-710.Full Text via DOI: 10.1042/cs20200016
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2019
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2019Brain natriuretic peptide mitigates TIMP2 induction and reinstates extracellular matrix catabolic activity via GSK3 beta inhibition in glomerular podocytes exposed to a profibrogenic milieu. AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH. 11:964-+.
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2019Lithium targeting of AMPK protects against cisplatin-induced acute kidney injury by enhancing autophagy in renal proximal tubular epithelial cells. FASEB JOURNAL. 33:14370-14381.Full Text via DOI: 10.1096/fj.201901712r
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2018Ecdysone Elicits Chronic Renal Impairment via Mineralocorticoid-Like Pathogenic Activities. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY. 49:1633-1645.Full Text via DOI: 10.1159/000493499
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2018Effectiveness and Safety of Peritoneal Dialysis Treatment in Patients with Refractory Congestive Heart Failure due to Chronic Cardiorenal Syndrome. BIOMED RESEARCH INTERNATIONAL.Full Text via DOI: 10.1155/2018/6529283
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2018Blocking Macrophage Migration Inhibitory Factor Protects Against Cisplatin-Induced Acute Kidney Injury in Mice. Molecular Therapy. 26:2523-2532.Full Text via DOI: 10.1016/j.ymthe.2018.07.014
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2017Acquired Resistance to Corticotropin Therapy in Nephrotic Syndrome: Role of De Novo Neutralizing Antibody. PEDIATRICS. 140:e20162169.Full Text via DOI: 10.1542/peds.2016-2169
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2017Valproate hampers podocyte acquisition of immune phenotypes via intercepting the GSK3β facilitated NFkB activation. ONCOTARGET. 8:88332-88344.Full Text via DOI: 10.18632/oncotarget.19917
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2016Activation of FXR protects against renal fibrosis via suppressing Smad3 expression. SCIENTIFIC REPORTS. 6:37234.Full Text via DOI: 10.1038/srep37234
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2016Enhancer of Zeste Homolog 2 Inhibition Attenuates Renal Fibrosis by Maintaining Smad7 and Phosphatase and Tensin Homolog Expression. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 27:2092-2108.Full Text via DOI: 10.1681/asn.2015040457
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2016Genetic and Pharmacologic Targeting of Glycogen Synthase Kinase 3β Reinforces the Nrf2 Antioxidant Defense against Podocytopathy. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 27:2289-2308.Full Text via DOI: 10.1681/asn.2015050565
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2016MC1R is dispensable for the proteinuria reducing and glomerular protective effect of melanocortin therapy. SCIENTIFIC REPORTS. 6:27589.Full Text via DOI: 10.1038/srep27589
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2016Rescue therapy with Tanshinone IIA hinders transition of acute kidney injury to chronic kidney disease via targeting GSK3β. SCIENTIFIC REPORTS. 6:36698.Full Text via DOI: 10.1038/srep36698
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2016The β isoform of GSK3 mediates podocyte autonomous injury in proteinuric glomerulopathy. The Journal of Pathology. 239:23-35.Full Text via DOI: 10.1002/path.4692
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2016What we need to know about the effect of lithium on the kidney. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 311:F1168-F1171.Full Text via DOI: 10.1152/ajprenal.00145.2016
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2015Fine-tuning of NFκB by glycogen synthase kinase 3β directs the fate of glomerular podocytes upon injury. KIDNEY INTERNATIONAL. 87:1176-1190.Full Text via DOI: 10.1038/ki.2014.428
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2015Glycogen Synthase Kinase 3β Orchestrates Microtubule Remodeling in Compensatory Glomerular Adaptation to Podocyte Depletion. JOURNAL OF BIOLOGICAL CHEMISTRY. 290:1348-1363.Full Text via DOI: 10.1074/jbc.m114.593830
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2015P2X7 receptor inhibition protects against ischemic acute kidney injury in mice. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 308:C463-C472.Full Text via DOI: 10.1152/ajpcell.00245.2014
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2015Pharmacological targeting of GSK3β confers protection against podocytopathy and proteinuria by desensitizing mitochondrial permeability transition. British Journal of Pharmacology. 172:895-909.Full Text via DOI: 10.1111/bph.12952
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2015Remote Ischemic Preconditioning for Kidney Protection: GSK3β-Centric Insights Into the Mechanism of Action. AMERICAN JOURNAL OF KIDNEY DISEASES. 66:846-856.Full Text via DOI: 10.1053/j.ajkd.2015.06.026
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2015Tanshinone IIA Attenuates Renal Fibrosis after Acute Kidney Injury in a Mouse Model through Inhibition of Fibrocytes Recruitment. BIOMED RESEARCH INTERNATIONAL. 2015:1-10.Full Text via DOI: 10.1155/2015/867140
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2015The redox sensitive glycogen synthase kinase 3β suppresses the self-protective antioxidant response in podocytes upon oxidative glomerular injury. ONCOTARGET. 6:39493-39506.Full Text via DOI: 10.18632/oncotarget.6303
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2015Therapeutic targeting of GSK3β enhances the Nrf2 antioxidant response and confers hepatic cytoprotection in hepatitis C. GUT. 64:168-179.Full Text via DOI: 10.1136/gutjnl-2013-306043
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2014Blocking Sirtuin 1 and 2 Inhibits Renal Interstitial Fibroblast Activation and Attenuates Renal Interstitial Fibrosis in Obstructive Nephropathy. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 350:243-256.Full Text via DOI: 10.1124/jpet.113.212076
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2014Class I HDAC activity is required for renal protection and regeneration after acute kidney injury. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 307:F303-F316.Full Text via DOI: 10.1152/ajprenal.00102.2014
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2014Delayed Administration of a Single Dose of Lithium Promotes Recovery from AKI. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 25:488-500.Full Text via DOI: 10.1681/asn.2013040350
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2014Gene Therapy with Biosynthetic Nanoscale Peptide Cecropin A Driven by the Survivin Promoter for Hepatocarcinoma Cells. Journal of Biomedical Nanotechnology. 10:1391-1399.Full Text via DOI: 10.1166/jbn.2014.1891
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2014Glycogen Synthase Kinase 3β Dictates Podocyte Motility and Focal Adhesion Turnover by Modulating Paxillin Activity. AMERICAN JOURNAL OF PATHOLOGY. 184:2742-2756.Full Text via DOI: 10.1016/j.ajpath.2014.06.027
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2014Inhibitory Effect of Biosynthetic Nanoscale Peptide Melittin on Hepatocellular Carcinoma, Driven by Survivin Promoter. Journal of Biomedical Nanotechnology. 10:695-706.Full Text via DOI: 10.1166/jbn.2014.1830
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2014Leveraging Melanocortin Pathways to Treat Glomerular Diseases. Advances in Chronic Kidney Disease. 21:134-151.Full Text via DOI: 10.1053/j.ackd.2013.09.004
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2013Adrenalectomy amplifies aldosterone induced injury in cardiovascular tissue: An effect attenuated by adrenally derived steroids. STEROIDS. 78:347-355.Full Text via DOI: 10.1016/j.steroids.2012.12.007
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2013Adrenocorticotropic hormone ameliorates acute kidney injury by steroidogenic-dependent and -independent mechanisms. KIDNEY INTERNATIONAL. 83:635-646.Full Text via DOI: 10.1038/ki.2012.447
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2013Redox-sensitive glycogen synthase kinase 3β-directed control of mitochondrial permeability transition: rheostatic regulation of acute kidney injury. FREE RADICAL BIOLOGY AND MEDICINE. 65:849-858.Full Text via DOI: 10.1016/j.freeradbiomed.2013.08.169
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2013Suicide gene therapy for hepatocellular carcinoma cells by survivin promoter-driven expression of the herpes simplex virus thymidine kinase gene. ONCOLOGY REPORTS. 29:1435-1440.Full Text via DOI: 10.3892/or.2013.2248
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2013Sustained Activation of EGFR Triggers Renal Fibrogenesis after Acute Kidney Injury. AMERICAN JOURNAL OF PATHOLOGY. 183:160-172.Full Text via DOI: 10.1016/j.ajpath.2013.04.005
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2013Targeting and Eradicating Hepatic Cancer Cells with a Cancer-Specific Vector Carrying the Buforin II Gene. Cancer Biotherapy and Radiopharmaceuticals. 28:623-630.Full Text via DOI: 10.1089/cbr.2012.1469
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2012Distinct roles of two alternative splice variants of matrilin-2 in protein oligomerization and proteolysis. Molecular Medicine Reports. 6:1204-1210.Full Text via DOI: 10.3892/mmr.2012.1056
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2012Evaluation of a Recombinant Multiepitope Peptide for Serodiagnosis of Toxoplasma gondii Infection. CLINICAL AND VACCINE IMMUNOLOGY. 19:338-342.Full Text via DOI: 10.1128/cvi.05553-11
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2012Genetic or Pharmacologic Blockade of EGFR Inhibits Renal Fibrosis. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 23:854-867.Full Text via DOI: 10.1681/asn.2011050493
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2012Inhibition of glycogen synthase kinase-3β prevents NSAID-induced acute kidney injury. KIDNEY INTERNATIONAL. 81:662-673.Full Text via DOI: 10.1038/ki.2011.443
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2012Suramin Alleviates Glomerular Injury and Inflammation in the Remnant Kidney. PLOS ONE. 7:e36194.Full Text via DOI: 10.1371/journal.pone.0036194
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2012The renaissance of corticotropin therapy in proteinuric nephropathies. Nature Reviews Nephrology. 8:122-128.Full Text via DOI: 10.1038/nrneph.2011.190
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2011Aldosterone-Induced Fibrosis in the Kidney: Questions and Controversies. AMERICAN JOURNAL OF KIDNEY DISEASES. 58:471-479.Full Text via DOI: 10.1053/j.ajkd.2011.03.029
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2011Conditional ablation of glycogen synthase kinase 3β in postnatal mouse kidney. LABORATORY INVESTIGATION. 91:85-96.Full Text via DOI: 10.1038/labinvest.2010.142
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2011ERK pathway mediates P2X7 expression and cell death in renal interstitial fibroblasts exposed to necrotic renal epithelial cells. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 301:F650-F659.Full Text via DOI: 10.1152/ajprenal.00215.2011
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2011P2X7receptors mediate deleterious renal epithelial-fibroblast cross talk. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 300:F62-F70.Full Text via DOI: 10.1152/ajprenal.00473.2010
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2010A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy. KIDNEY INTERNATIONAL. 78:257-268.Full Text via DOI: 10.1038/ki.2010.154
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2010Direct fibrogenic effects of aldosterone on normotensive kidney: an effect modified by 11β-HSD activity. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 298:F1178-F1187.Full Text via DOI: 10.1152/ajprenal.00532.2009
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2010Inhibiting nonmuscle myosin II impedes inflammatory infiltration and ameliorates progressive renal disease. LABORATORY INVESTIGATION. 90:448-458.Full Text via DOI: 10.1038/labinvest.2009.142
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2010The mechanism of atopic march may be the ‘social’ event of cells and molecules (Review). INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 26.Full Text via DOI: 10.3892/ijmm_00000525
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2009Transglutaminase-1 Regulates Renal Epithelial Cell Proliferation through Activation of Stat-3. JOURNAL OF BIOLOGICAL CHEMISTRY. 284:3345-3353.Full Text via DOI: 10.1074/jbc.m808396200
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2009Transglutaminase-1 protects renal epithelial cells from hydrogen peroxide-induced apoptosis through activation of STAT3 and AKT signaling pathways. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 297:F1361-F1370.Full Text via DOI: 10.1152/ajprenal.00251.2009
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2008Candesartan suppresses chronic renal inflammation by a novel antioxidant action independent of AT1R blockade. KIDNEY INTERNATIONAL. 74:1128-1138.Full Text via DOI: 10.1038/ki.2008.380
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2008Co-localization of glucocorticoid metabolizing and prostaglandin synthesizing enzymes in rat kidney and liver. LIFE SCIENCES. 83:725-731.Full Text via DOI: 10.1016/j.lfs.2008.09.015
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2008Glycogen Synthase Kinase 3β: A Novel Marker and Modulator of Inflammatory Injury in Chronic Renal Allograft Disease. AMERICAN JOURNAL OF TRANSPLANTATION. 8:1852-1863.Full Text via DOI: 10.1111/j.1600-6143.2008.02319.x
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2008Hepatocyte Growth Factor Suppresses Proinflammatory NFκB Activation through GSK3β Inactivation in Renal Tubular Epithelial Cells. JOURNAL OF BIOLOGICAL CHEMISTRY. 283:7401-7410.Full Text via DOI: 10.1074/jbc.m710396200
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2008Human renal 11β-hydroxysteroid dehydrogenase 1 functions and co-localizes with COX-2. LIFE SCIENCES. 82:631-637.Full Text via DOI: 10.1016/j.lfs.2007.12.019
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2008Variable expression of 11β Hydroxysteroid dehydrogenase (11β-HSD) isoforms in vascular endothelial cells. STEROIDS. 73:1187-1196.Full Text via DOI: 10.1016/j.steroids.2008.05.009
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2007Epistatic effect of plasminogen activator inhibitor 1 and β-Fibrinogen genes on risk of glomerular microthrombosis in lupus nephritis: Interaction with environmental/clinical factors. ARTHRITIS AND RHEUMATISM. 56:1608-1617.Full Text via DOI: 10.1002/art.22598
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2007Long-Term, High-Dosage Candesartan Suppresses Inflammation and Injury in Chronic Kidney Disease: Nonhemodynamic Renal Protection. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 18:750-759.Full Text via DOI: 10.1681/asn.2006070770
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2006Anti-Inflammatory Effect of Hepatocyte Growth Factor in Chronic Kidney Disease: Targeting the Inflamed Vascular Endothelium. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 17:2464-2473.Full Text via DOI: 10.1681/asn.2006020185
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2006Hepatocyte growth factor suppresses acute renal inflammation by inhibition of endothelial E-selectin. KIDNEY INTERNATIONAL. 69:1166-1174.Full Text via DOI: 10.1038/sj.ki.5000246
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2005Activation of PI3K–Akt–GSK3β pathway mediates hepatocyte growth factor inhibition of RANTES expression in renal tubular epithelial cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 330:27-33.Full Text via DOI: 10.1016/j.bbrc.2005.02.122
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2005Hepatocyte growth factor induces an endothelin-mediated decline in glomerular filtration rate. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 288:F8-F15.Full Text via DOI: 10.1152/ajprenal.00435.2003
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2004Hepatocyte Growth Factor Ameliorates Renal Interstitial Inflammation in Rat Remnant Kidney by Modulating Tubular Expression of Macrophage Chemoattractant Protein-1 and RANTES. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 15:2868-2881.Full Text via DOI: 10.1097/01.asn.0000141962.44300.3a
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2004Hepatocyte growth factor ameliorates progression of interstitial fibrosis in rats with established renal injury. KIDNEY INTERNATIONAL. 65:409-419.Full Text via DOI: 10.1111/j.1523-1755.2004.00417.x
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2003Hepatocyte Growth Factor Modulates Matrix Metalloproteinases and Plasminogen Activator/Plasmin Proteolytic Pathways in Progressive Renal Interstitial Fibrosis. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 14:3047-3060.Full Text via DOI: 10.1097/01.asn.0000098686.72971.db
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2003Impact of Fipronil on Crustacean Aquatic Organisms in a Paddy Field-Fishpond Ecosystem. Bulletin of Environmental Contamination and Toxicology. 70:746-752.Full Text via DOI: 10.1007/s00128-003-0046-9
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2002Sex Differences in Estrogen Receptor Gene Polymorphism and Its Association with Lupus Nephritis in Chinese. Nephron. 90:174-180.Full Text via DOI: 10.1159/000049039
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Conference Poster (Faculty180)
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Correction (Web of Science)
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2022Corrigendum to Fang Y, Chen B, Gong AY, et al. “The ketone body β-hydroxybutyrate mitigates the senescence response of glomerular podocytes to diabetic insults.” Kidney Int. 2021;100:1037–1053. KIDNEY INTERNATIONAL. 1301-1302.Full Text via DOI: 10.1016/j.kint.2022.04.002
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2020Author Correction: MC1R is dispensable for the proteinuria reducing and glomerular protective effect of melanocortin therapy. SCIENTIFIC REPORTS. 15608.Full Text via DOI: 10.1038/s41598-020-72744-7
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Early Access (Web of Science)
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2020Melanocortin 5 receptor signaling pathway in health and disease. CELLULAR AND MOLECULAR LIFE SCIENCES.Full Text via DOI: 10.1007/s00018-020-03511-0 PMID: 32248247
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Editorial Material (Web of Science)
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2022The Janus view: dual roles for hypoxia-inducible factor in renal repair after acute kidney injury. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. F1-F3.Full Text via DOI: 10.1152/ajprenal.00130.2022 PMID: 35635325
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Review Article (Web of Science)
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2021Therapeutic Targeting of SGLT2: A New Era in the Treatment of Diabetes and Diabetic Kidney Disease. FRONTIERS IN ENDOCRINOLOGY.Full Text via DOI: 10.3389/fendo.2021.749010 PMID: 34790170
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2021Melanocortin System in Kidney Homeostasis and Disease: Novel Therapeutic Opportunities. FRONTIERS IN PHYSIOLOGY.Full Text via DOI: 10.3389/fphys.2021.651236 PMID: 33716796
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2020The ageing kidney: Molecular mechanisms and clinical implications. AGEING RESEARCH REVIEWS.Full Text via DOI: 10.1016/j.arr.2020.101151 PMID: 32835891
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2019Mineralocorticoid receptor: A hidden culprit for hemodialysis vascular access dysfunction. EBIOMEDICINE. 621-627.Full Text via DOI: 10.1016/j.ebiom.2018.11.054
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2019Long noncoding RNA: an emerging player in diabetes and diabetic kidney disease. CLINICAL SCIENCE. 1321-1339.Full Text via DOI: 10.1042/cs20190372
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2018Targeting Regulatory T Cells for Transplant Tolerance: New Insights and Future Perspectives. KIDNEY DISEASES. 205-213.Full Text via DOI: 10.1159/000490703 PMID: 30574497
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2015Therapeutic targeting of aldosterone: a novel approach to the treatment of glomerular disease. CLINICAL SCIENCE. 527-535.Full Text via DOI: 10.1042/cs20140432
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Contact
full name
- Rujun Gong