Zahoor A. Shah
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Associate Dean for Graduate Education and Research
Professor
Associate Professor
Vice Chair
Program Director
Assistant Professor, Medicinal and Biological Chemistry , College of Pharmacy and Pharmaceutical Sciences
Contact Info
Overview
overview
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Dr. Shah obtained a doctorate (Ph.D.) in Toxicology from Hamdard University, New Delhi and postdoctoral trainings at The University of Louisville, Louisville KY and Johns Hopkins University, Baltimore, MD. Currently, Dr. Shah is an Associate Professor and Vice Chair in the Department of Medicinal and Biological Chemistry at the College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, Toledo, OH. The focus of Dr. Shah’s research is to look for potential molecular targets and develop drugs for the treatment of ischemic and hemorrhagic brain injury. Dr. Shah has published more than 83 scientific publications and trained a number of graduate and undergraduate students. Dr. Shah has also been inducted in NIH study section review committees.
Publications
selected publications
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Article (Faculty180)
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2023Association between insulin and Nrf2 signalling pathway in Alzheimer's disease: A molecular landscape. Life sciences. 328:121899.
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2023Astrocytes in functional recovery following central nervous system injuries. The Journal of physiology.
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2023Behavioural, genomics and proteomic approach to examine Alzheimer's disease in zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 271:109636.
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2023Development and validation of LC-MS/MS method for determining the metabolic stability, pharmacokinetics, and dose proportionality of a novel anti-inflammatory cofilin inhibitor. Journal of pharmaceutical and biomedical analysis. 226:115258.
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2023Neuroprotection of Sex Bias: A Protective Response to Traumatic Brain Injury in the Females. CNS & neurological disorders drug targets.
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2023Stroke: Molecular mechanisms and therapies: Update on recent developments. Neurochemistry international. 162:105458.
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2023Synthesis and Pharmacological Evaluation of Novel Triazole-Pyrimidine Hybrids as Potential Neuroprotective and Anti-neuroinflammatory Agents. Pharmaceutical research. 40:167-185.
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2023The ER chaperone, BIP protects Microglia from ER stress-mediated Apoptosis in Hyperglycemia. Neurochemistry international. 169:105573.
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2023Use of mesenchymal stem cell therapy in COVID-19 related strokes. Neural regeneration research. 18:1881-1883.
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2022Oxidative stress in chronic and acute CNS insults. Neurochemistry international. 153:105274.
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2022Perspective on the relationship between microbiota dysbiosis and neuroinflammation: probiotics as a treatment option. Neural regeneration research. 17:1969-1970.
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2022Small interfering RNAs based therapies for intracerebral hemorrhage: challenges and progress in drug delivery systems. Neural regeneration research. 17:1717-1725.
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2022The influence of gut microbiota alteration on age-related neuroinflammation and cognitive decline. Neural regeneration research. 17:2407-2412.
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2021Inflammation Drives Alzheimer's Disease: Emphasis on 5-lipoxygenase Pathways. Current neuropharmacology. 19:885-895.
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2021Intracerebral Hemorrhage and Diabetes Mellitus: Blood-Brain Barrier Disruption, Pathophysiology, and Cognitive Impairments. CNS & neurological disorders drug targets.
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2021Involvement of the dopaminergic system in the reward-related behavior of pregabalin. Scientific reports. 11:10577.
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2021Mechanistic role of boswellic acids in Alzheimer's disease: Emphasis on anti-inflammatory properties. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 144:112250.
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2021Potential Benefits of N-Acetylcysteine in Preventing Pregabalin-Induced Seeking-Like Behavior. Healthcare (Basel, Switzerland). 9.
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2021Quantitative response of wheat to sowing dates and irrigation regimes using CERES-Wheat model. Saudi journal of biological sciences. 28:6198-6208.
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2021The structural simplification of lysergic acid as a natural lead for synthesizing novel anti-Alzheimer agents. Bioorganic & medicinal chemistry letters. 47:128205.
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2021Type-I diabetes aggravates post-hemorrhagic stroke cognitive impairment by augmenting oxidative stress and neuroinflammation in mice. Neurochemistry international. 149:105151.
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2020Gabapentin-induced drug-seeking-like behavior: a potential role for the dopaminergic system. Scientific reports. 10:10445.
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2020
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2020Sex differences in pregabalin-seeking like behavior in a conditioned place preference paradigm. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. 28:1749-1755.
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2020The role of cofilin in age-related neuroinflammation. Neural regeneration research. 15:1451-1459.
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2019Pregabalin: Potential for Addiction and a Possible Glutamatergic Mechanism. Scientific reports. 9:15136.
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2019The GSK3β inhibitor, TDZD-8, rescues cognition in a zebrafish model of okadaic acid-induced Alzheimer's disease. Neurochemistry international. 122:31-37.
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2019
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2018A Bioactive Resveratrol Trimer from the Stem Bark of the Sri Lankan Endemic Plant Vateria copallifera. Journal of natural products.
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2018
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2018Cofilin Mediates LPS-Induced Microglial Cell Activation and Associated Neurotoxicity Through Activation of NF-κB and JAK-STAT Pathway. Molecular neurobiology. 55:1676-1691.
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2018Correction to Furoxans (Oxadiazole- N-oxides) with Attenuated Reactivity Are Neuroprotective, Cross the Blood Brain Barrier, and Improve Passive Avoidance Memory. Journal of medicinal chemistry. 61:5773.
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2018Development of a reactive oxygen species-sensitive nitric oxide synthase inhibitor for the treatment of ischemic stroke. Free Radical Biology and Medicine. 115:395.
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2018Development of a reactive oxygen species-sensitive nitric oxide synthase inhibitor for the treatment of ischemic stroke. Free Radical Biology and Medicine. 115:395.
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2018Development of a reactive oxygen species-sensitive nitric oxide synthase inhibitor for the treatment of ischemic stroke. Free Radical Biology and Medicine. 115:395.
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2018Furoxans (Oxadiazole-4 N-oxides) with Attenuated Reactivity are Neuroprotective, Cross the Blood Brain Barrier, and Improve Passive Avoidance Memory. Journal of Medicinal Chemistry. 61:4593.
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2018Furoxans (Oxadiazole-4 N-oxides) with Attenuated Reactivity are Neuroprotective, Cross the Blood Brain Barrier, and Improve Passive Avoidance Memory. Journal of medicinal chemistry. 61:4593-4607.
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2018Lanthionine ketimine-5-ethyl ester provides neuroprotection in a zebrafish model of okadaic acid-induced Alzheimer's disease. Neurochemistry international. 115:61-68.
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2017Bioactivities of n-hexane fraction of Vateria copallifera and GC--MS analysis of its phytoconstituents. Industrial crops and products. 97:87.
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2017Cofilin signaling in hemin-induced microglial activation and inflammation. Journal of neuroimmunology. 313:46-55.
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2017
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2017Tanshinone IIA Inhibits VEGF Secretion and HIF-1α Expression in Cultured Human Retinal Pigment Epithelial Cells under Hypoxia. Current eye research. 42:1667-1673.
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2017The Interplay between Cofilin and Phospho-Cofilin: Its Role in Maintaining Blood Brain Barrier Integrity. CNS & neurological disorders drug targets. 16:279-290.
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2016Cofilin Inhibition Restores Neuronal Cell Death in Oxygen--Glucose Deprivation Model of Ischemia. Molecular neurobiology. 53:867.
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2016Cofilin as a promising therapeutic target for ischemic and hemorrhagic stroke. Translational stroke research. 7:33.
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2016Development of a novel and robust pharmacological model of okadaic acid-induced Alzheimerâs disease in zebrafish. CNS \& Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS \& Neurological Disorders). 15:86.
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2016Dry Eye Disease: Present Challenges in the Management and Future Trends. Current pharmaceutical design. 22:4470-90.
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2016Ginkgo biloba extract prevents female mice from ischemic brain damage and the mechanism is independent of the HO1/Wnt pathway. Translational stroke research. 7:120.
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2016Protective role of arginase II in cerebral ischemia and excitotoxicity. Journal of neurology and neuroscience. 7.
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2016Transgenic mice overexpressing human angiotensin I receptor gene are susceptible to stroke injury. Molecular neurobiology. 53:1533.
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2015Current perspectives on the beneficial role of Ginkgo biloba in neurological and cerebrovascular disorders. Integrative medicine insights. 10:IMI.
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2015Functional interaction between Na/K-ATPase and NMDA receptor in cerebellar neurons. Molecular neurobiology. 52:1726.
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2015Ouabain-induced signaling and cell survival in SK-N-SH neuroblastoma cells differentiated by retinoic acid. CNS \& Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS \& Neurological Disorders). 14:1343.
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2015Withania somnifera improves ischemic stroke outcomes by attenuating PARP1-AIF-mediated caspase-independent apoptosis. Molecular neurobiology. 52:1093.
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2015Withania somnifera: a pre-clinical study on neuroregenerative therapy for stroke. Neural regeneration research. 10:183.
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2014Flavonoids isolated from Rumex aquaticus exhibit neuroprotective and neurorestorative properties by enhancing neurite outgrowth and synaptophysin. CNS \& Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS \& Neurological Disorders). 13:1458.
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2014Heme oxygenase 1-mediated neurogenesis is enhanced by Ginkgo biloba (EGb 761\textregistered) after permanent ischemic stroke in mice. Molecular neurobiology. 49:945.
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2014Repair and regeneration properties of Ginkgo biloba after ischemic brain injury. Neural regeneration research. 9:1104.
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2014Sesamin attenuates neurotoxicity in mouse model of ischemic brain stroke. Neurotoxicology. 45:100.
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2014The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway. Journal of Cerebral Blood Flow \& Metabolism. 34:735.
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2013Ginkgo biloba prevents transient global ischemia-induced delayed hippocampal neuronal death through antioxidant and anti-inflammatory mechanism. Neurochemistry international. 62:189.
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2013Natural products inspired synthesis of neuroprotective agents against H 2 O 2-induced cell death. Bioorganic \& medicinal chemistry letters. 23:1232.
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2013Single-bilayer graphene oxide sheet tolerance and glutathione redox system significance assessment in faba bean (Vicia faba L.). Journal of nanoparticle research. 15:1770.
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2012A derivative of the CRMP2 binding compound lanthionine ketimine provides neuroprotection in a mouse model of cerebral ischemia. Neurochemistry international. 61:1357.
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2012Calcium alginate nanoparticles synthesized through a novel interfacial cross-linking method as a potential protein drug delivery system. Journal of pharmaceutical sciences. 101:2177.
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2012Preconditioning with Ginkgo biloba (EGb 761\textregistered) provides neuroprotection through HO1 and CRMP2. Neurobiology of disease. 46:180.
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2012Sirtuins in neurodegenerative diseases: a biological-chemical perspective. Neurodegenerative Diseases. 9:1.
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2011
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2011Simvastatin and other HMG-CoA reductase inhibitors on brain cholesterol levels in Alzheimer's disease. Current Alzheimer Research. 8:434.
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2010Neuroprotective properties of prostaglandin I2 IP receptor in focal cerebral ischemia. Neuroscience. 170:317.
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2010The PGE 2 EP2 receptor and its selective activation are beneficial against ischemic stroke. Experimental \& translational stroke medicine. 2:12.
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2010The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway. Journal of Cerebral Blood Flow \& Metabolism. 30:1951.
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2009Heme oxygenase 1 is associated with ischemic preconditioning-induced protection against brain ischemia. Neurobiology of disease. 35:264.
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2009Use of an Optimized Transient Occlusion of the Middle Cerebral Artery Protocol for the Mouse Stroke Model (vol 15, pg 133, 2006). JOURNAL OF STROKE \& CEREBROVASCULAR DISEASES. 18:171.
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2008Erectile dysfunction in a murine model of sleep apnea. American journal of respiratory and critical care medicine. 178:644.
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2007Role of combined administration of Tiron and glutathione against aluminum-induced oxidative stress in rat brain. Journal of Trace Elements in Medicine and Biology. 21:63.
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2007Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury. Neuroscience. 147:53.
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2006Immobilization stress causes extra-cellular oxidant--antioxidant imbalance in rats: Restoration by L-NAME and vitamin E. European neuropsychopharmacology. 16:260.
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2006Serum proteomic patterns associated with sleep-disordered breathing in children. Pediatric research. 59:466.
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2006
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2006Use of an optimized transient occlusion of the middle cerebral artery protocol for the mouse stroke model. Journal of Stroke and Cerebrovascular Diseases. 15:133.
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2005Attenuation of Stress-Elicited Brain Catecholamines, Serotonin and Plasma Corticosterone Levels by Calcined Gold Preparations Used in Indian System of Medicine. Basic \& clinical pharmacology \& toxicology. 96:469.
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2005Cerebroprotective effect of Korean ginseng tea against global and focal models of ischemia in rats. Journal of Ethnopharmacology. 101:299.
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2005Tyrosine hydroxylase expression and activity in the rat brain: differential regulation after long-term intermittent or sustained hypoxia. Journal of applied physiology. 99:642.
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2003Ginkgo biloba normalises stress-elevated alterations in brain catecholamines, serotonin and plasma corticosterone levels. European neuropsychopharmacology. 13:321.
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2003
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2002Antioxidant/restorative effects of calcined gold preparations used in Indian systems of medicine against global and focal models of ischaemia. Pharmacology \& toxicology. 90:254.
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2002
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2001Low impact factors for Indian journals: Do factors other than quality influence?. CURRENT SCIENCE-BANGALORE-. 81:867.
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Protective Role of Arginase II in Cerebral Ischemia and Excitotoxicity. Journal of neurology and neuroscience. 7.
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Article (Web of Science)
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2023Stroke: Molecular mechanisms and therapies: Update on recent developments. NEUROCHEMISTRY INTERNATIONAL. 162.Full Text via DOI: 10.1016/j.neuint.2022.105458 PMID: 36460240
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2022Synthesis and Pharmacological Evaluation of Novel Triazole-Pyrimidine Hybrids as Potential Neuroprotective and Anti-neuroinflammatory Agents. PHARMACEUTICAL RESEARCH.Full Text via DOI: 10.1007/s11095-022-03429-1 PMID: 36376607
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2022First-in-Class Dual Mechanism Ferroptosis-HDAC Inhibitor Hybrids. JOURNAL OF MEDICINAL CHEMISTRY.Full Text via DOI: 10.1021/acs.jmedchem.2c01276 PMID: 36306372
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2022Larvicidal activity of Artemisia absinthium extracts with special reference to inhibition of detoxifying enzymes in larvae of Aedes aegypti L. JOURNAL OF KING SAUD UNIVERSITY SCIENCE. 34.Full Text via DOI: 10.1016/j.jksus.2022.102248
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2022Perspective on the relationship between microbiota dysbiosis and neuroinflammation: probiotics as a treatment option. NEURAL REGENERATION RESEARCH. 17:1969-1970.Full Text via DOI: 10.4103/1673-5374.335150 PMID: 35142679
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2022Synthesis and Development of a Novel First-in-Class Cofilin Inhibitor for Neuroinflammation in Hemorrhagic Brain Injury br. ACS CHEMICAL NEUROSCIENCE. 13:1014-1029.Full Text via DOI: 10.1021/acschemneuro.2c00010 PMID: 35302736
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2021Type-I diabetes aggravates post-hemorrhagic stroke cognitive impairment by augmenting oxidative stress and neuroinflammation in mice. NEUROCHEMISTRY INTERNATIONAL. 149.Full Text via DOI: 10.1016/j.neuint.2021.105151 PMID: 34348124
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2021The structural simplification of lysergic acid as a natural lead for synthesizing novel anti-Alzheimer agents. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 47.Full Text via DOI: 10.1016/j.bmcl.2021.128205 PMID: 34139326
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2021Involvement of the dopaminergic system in the reward-related behavior of pregabalin. SCIENTIFIC REPORTS. 11.Full Text via DOI: 10.1038/s41598-021-88429-8 PMID: 34011976
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2021Potential Benefits of N-Acetylcysteine in Preventing Pregabalin-Induced Seeking-Like Behavior. HEALTHCARE. 9.Full Text via DOI: 10.3390/healthcare9040376 PMID: 33805329
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2021Inflammation Drives Alzheimer's Disease: Emphasis on 5-lipoxygenase Pathways. CURRENT NEUROPHARMACOLOGY. 19:885-895.Full Text via DOI: 10.2174/1570159x18666200924122732
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2020Sex differences in pregabalin-seeking like behavior in a conditioned place preference paradigm. SAUDI PHARMACEUTICAL JOURNAL. 28:1749-1755.Full Text via DOI: 10.1016/j.jsps.2020.11.001 PMID: 33424265
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2020Neuroprotective and Anti-neuroinflammatory Properties of Ebselen Derivatives and Their Potential to Inhibit Neurodegeneration. ACS CHEMICAL NEUROSCIENCE. 11:3008-3016.Full Text via DOI: 10.1021/acschemneuro.0c00328 PMID: 32840996
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2020Gabapentin-induced drug-seeking-like behavior: a potential role for the dopaminergic system. SCIENTIFIC REPORTS. 10.Full Text via DOI: 10.1038/s41598-020-67318-6 PMID: 32591630
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2020Design of neural network based intelligent computing for neumerical treatment of unsteady 3D flow of Eyring-Powell magneto-nanofluidic model. Journal of Materials Research and Technology. 9:14372-14387.Full Text via DOI: 10.1016/j.jmrt.2020.09.098
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2019Pregabalin: Potential for Addiction and a Possible Glutamatergic Mechanism. SCIENTIFIC REPORTS. 9.Full Text via DOI: 10.1038/s41598-019-51556-4 PMID: 31641170
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2019Tribulusterine Containing Tribulus terrestris Extract Exhibited Neuroprotection Through Attenuating Stress Kinases Mediated Inflammatory Mechanism: In Vitro and In Vivo Studies. NEUROCHEMICAL RESEARCH. 44:1228-1242.Full Text via DOI: 10.1007/s11064-019-02768-7 PMID: 30863969
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2019The GSK3 beta inhibitor, TDZD-8, rescues cognition in a zebrafish model of okadaic acid-induced Alzheimer's disease. NEUROCHEMISTRY INTERNATIONAL. 122:31-37.Full Text via DOI: 10.1016/j.neuint.2018.10.022
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2018A Bioactive Resveratrol Trimer from the Stem Bark of the Sri Lankan Endemic Plant Vateria copallifera. JOURNAL OF NATURAL PRODUCTS. 81:1693-1700.Full Text via DOI: 10.1021/acs.jnatprod.7b00892
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2018Cofilin Knockdown Attenuates Hemorrhagic Brain Injury-induced Oxidative Stress and Microglial Activation in Mice. NEUROSCIENCE. 383:33-45.Full Text via DOI: 10.1016/j.neuroscience.2018.04.036
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2018Furoxans (Oxadiazole-4N-oxides) with Attenuated Reactivity are Neuroprotective, Cross the Blood Brain Barrier, and Improve Passive Avoidance Memory. JOURNAL OF MEDICINAL CHEMISTRY. 61:4593-4607.Full Text via DOI: 10.1021/acs.jmedchem.8b00389
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2018Lanthionine ketimine-5-ethyl ester provides neuroprotection in a zebrafish model of okadaic acid-induced Alzheimer's disease. NEUROCHEMISTRY INTERNATIONAL. 115:61-68.Full Text via DOI: 10.1016/j.neuint.2018.02.002
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2018Cofilin Mediates LPS-Induced Microglial Cell Activation and Associated Neurotoxicity Through Activation of NF-kappa B and JAK-STAT Pathway. MOLECULAR NEUROBIOLOGY. 55:1676-1691.Full Text via DOI: 10.1007/s12035-017-0432-7
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2018Development of a reactive oxygen species-sensitive nitric oxide synthase inhibitor for the treatment of ischemic stroke. FREE RADICAL BIOLOGY AND MEDICINE. 115:395-404.Full Text via DOI: 10.1016/j.freeradbiomed.2017.12.027
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2017Cofilin signaling in hemin-induced microglial activation and inflammation. JOURNAL OF NEUROIMMUNOLOGY. 313:46-55.Full Text via DOI: 10.1016/j.jneuroim.2017.10.007
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2017HO1 and Wnt expression is independently regulated in female mice brains following permanent ischemic brain injury. BRAIN RESEARCH. 1662:1-6.Full Text via DOI: 10.1016/j.brainres.2017.02.006
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2017Bioactivities of n-hexane fraction of Vateria copallifera and GC-MS analysis of its phytoconstituents. INDUSTRIAL CROPS AND PRODUCTS. 97:87-92.Full Text via DOI: 10.1016/j.indcrop.2016.12.011
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2017Tanshinone IIA Inhibits VEGF Secretion and HIF-1 alpha Expression in Cultured Human Retinal Pigment Epithelial Cells under Hypoxia. CURRENT EYE RESEARCH. 42:1667-1673.Full Text via DOI: 10.1080/02713683.2017.1355467
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2016Ginkgo biloba Extract Prevents Female Mice from Ischemic Brain Damage and the Mechanism Is Independent of the HO1/Wnt Pathway. TRANSLATIONAL STROKE RESEARCH. 7:120-131.Full Text via DOI: 10.1007/s12975-015-0433-7
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2016Transgenic Mice Overexpressing Human Angiotensin I Receptor Gene Are Susceptible to Stroke Injury. MOLECULAR NEUROBIOLOGY. 53:1533-1539.Full Text via DOI: 10.1007/s12035-015-9109-2
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2016Cofilin Inhibition Restores Neuronal Cell Death in Oxygen-Glucose Deprivation Model of Ischemia. MOLECULAR NEUROBIOLOGY. 53:867-878.Full Text via DOI: 10.1007/s12035-014-9056-3
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2016Obesity and hyperglycemia lead to impaired post-ischemic recovery after permanent ischemia in mice. OBESITY. 24:417-423.Full Text via DOI: 10.1002/oby.21388
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2016Development of a Novel and Robust Pharmacological Model of Okadaic Acid-induced Alzheimer's Disease in Zebrafish. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. 15:86-94.Full Text via DOI: 10.2174/1871527314666150821105602
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2015Functional Interaction Between Na/K-ATPase and NMDA Receptor in Cerebellar Neurons. MOLECULAR NEUROBIOLOGY. 52:1726-1734.Full Text via DOI: 10.1007/s12035-014-8975-3
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2015Withania somnifera Improves Ischemic Stroke Outcomes by Attenuating PARP1-AIF-Mediated Caspase-Independent Apoptosis. MOLECULAR NEUROBIOLOGY. 52:1093-1105.Full Text via DOI: 10.1007/s12035-014-8907-2
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2015Ouabain-Induced Signaling and Cell Survival in SK-N-SH Neuroblastoma Cells Differentiated by Retinoic Acid. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. 14:1343-1349.Full Text via DOI: 10.2174/1871527314666150821103008
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2015Current Perspectives on the Beneficial Role of Ginkgo biloba in Neurological and Cerebrovascular Disorders. Integrative Medicine Insights. 10:IMI.S25054.Full Text via DOI: 10.4137/imi.s25054
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2014Characterization and Evaluation of 5-Fluorouracil-Loaded Solid Lipid Nanoparticles Prepared via a Temperature-Modulated Solidification Technique. AAPS PHARMSCITECH. 15:1498-1508.Full Text via DOI: 10.1208/s12249-014-0168-x
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2014Sesamin attenuates neurotoxicity in mouse model of ischemic brain stroke. NEUROTOXICOLOGY. 45:100-110.Full Text via DOI: 10.1016/j.neuro.2014.10.002
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2014Repair and regeneration properties of Ginkgo biloba after ischemic brain injury. NEURAL REGENERATION RESEARCH. 9:1104-1107.Full Text via DOI: 10.4103/1673-5374.135308
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2014Flavonoids Isolated from Rumex aquaticus Exhibit Neuroprotective and Neurorestorative Properties by Enhancing Neurite Outgrowth and Synaptophysin. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. 13:1458-1464.
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2014Flavonoids Isolated from Rumex aquaticus Exhibit Neuroprotective and Neurorestorative Properties by Enhancing Neurite Outgrowth and Synaptophysin. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. 13:1458-1464.Full Text via DOI: 10.2174/1871527313666141023154446
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2013Single-bilayer graphene oxide sheet tolerance and glutathione redox system significance assessment in faba bean (Vicia faba L.). JOURNAL OF NANOPARTICLE RESEARCH. 15.Full Text via DOI: 10.1007/s11051-013-1770-7
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2013Natural products inspired synthesis of neuroprotective agents against H2O2-induced cell death. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 23:1232-1237.Full Text via DOI: 10.1016/j.bmcl.2013.01.013
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2013Ginkgo biloba prevents transient global ischemia-induced delayed hippocampal neuronal death through antioxidant and anti-inflammatory mechanism. NEUROCHEMISTRY INTERNATIONAL. 62:189-197.Full Text via DOI: 10.1016/j.neuint.2012.11.017
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2012A derivative of the CRMP2 binding compound lanthionine ketimine provides neuroprotection in a mouse model of cerebral ischemia. NEUROCHEMISTRY INTERNATIONAL. 61:1357-1363.Full Text via DOI: 10.1016/j.neuint.2012.09.013
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2012Calcium alginate nanoparticles synthesized through a novel interfacial cross-linking method as a potential protein drug delivery system. JOURNAL OF PHARMACEUTICAL SCIENCES. 101:2177-2184.Full Text via DOI: 10.1002/jps.23104
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2012Preconditioning with Ginkgo biloba (EGb 761 (R)) provides neuroprotection through HO1 and CRMP2. NEUROBIOLOGY OF DISEASE. 46:180-189.Full Text via DOI: 10.1016/j.nbd.2012.01.006
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2011Simvastatin and Other HMG-CoA Reductase Inhibitors on Brain Cholesterol Levels in Alzheimer's Disease. CURRENT ALZHEIMER RESEARCH. 8:434-442.
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2011HEME OXYGENASE 1, BENEFICIAL ROLE IN PERMANENT ISCHEMIC STROKE AND IN GINGKO BILOBA (EGB 761) NEUROPROTECTION. NEUROSCIENCE. 180:248-255.Full Text via DOI: 10.1016/j.neuroscience.2011.02.031
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2011Simvastatin and Other HMG-CoA Reductase Inhibitors on Brain Cholesterol Levels in Alzheimers Disease. CURRENT ALZHEIMER RESEARCH. 8:434-442.Full Text via DOI: 10.2174/156720511795745393
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2010Neuroprotective properties of prostaglandin I2 IP receptor in focal cerebral ischemia. NEUROSCIENCE. 170:317-323.Full Text via DOI: 10.1016/j.neuroscience.2010.06.060
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2010The Flavanol (−)-Epicatechin Prevents Stroke Damage through the Nrf2/HO1 Pathway. Journal of Cerebral Blood Flow & Metabolism. 30:1951-1961.Full Text via DOI: 10.1038/jcbfm.2010.53
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2009Heme oxygenase 1 is associated with ischemic preconditioning-induced protection against brain ischemia. NEUROBIOLOGY OF DISEASE. 35:264-269.Full Text via DOI: 10.1016/j.nbd.2009.05.010
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2009Lipocalin-prostaglandin D synthase is a critical beneficial factor in transient and permanent focal cerebral ischemia. NEUROSCIENCE. 160:248-254.Full Text via DOI: 10.1016/j.neuroscience.2009.02.039
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2008Erectile Dysfunction in a Murine Model of Sleep Apnea. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 178:644-650.Full Text via DOI: 10.1164/rccm.200801-190oc
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2007Role of combined administration of Tiron and glutathione against aluminum-induced oxidative stress in rat brain. Journal of Trace Elements in Medicine and Biology. 21:63-70.Full Text via DOI: 10.1016/j.jtemb.2006.12.001
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2007Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury. NEUROSCIENCE. 147:53-59.Full Text via DOI: 10.1016/j.neuroscience.2007.02.066
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2006Immobilization stress causes extra-cellular oxidant–antioxidant imbalance in rats: Restoration by L-NAME and vitamin E. European Neuropsychopharmacology. 16:260-267.Full Text via DOI: 10.1016/j.euroneuro.2005.08.001
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2005Cerebroprotective effect of Korean ginseng tea against global and focal models of ischemia in rats. JOURNAL OF ETHNOPHARMACOLOGY. 101:299-307.Full Text via DOI: 10.1016/j.jep.2005.05.002
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2003Ginkgo biloba normalises stress-elevated alterations in brain catecholamines, serotonin and plasma corticosterone levels. European Neuropsychopharmacology. 13:321-325.Full Text via DOI: 10.1016/s0924-977x(03)00005-1
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2002Antioxidant/Restorative Effects of Calcined Gold Preparations Used in Indian Systems of Medicine against Global and Focal Models of Ischaemia. Pharmacology & Toxicology. 90:254-259.Full Text via DOI: 10.1034/j.1600-0773.2002.900505.x
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2002Protective effect of Tiron (4,5-dihydroxybenzene-1,3-disulfonic acid disodium salt) against beryllium-induced maternal and fetal toxicity in rats. Archives of Toxicology. 76:442-448.Full Text via DOI: 10.1007/s00204-002-0356-4
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Chapter (Faculty180)
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20147 Neurodegenerative. Diet, Exercise, and Chronic Disease: The Biological Basis of Prevention. 339.
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2014Neurodegenerative Disease. Diet, Exercise, and Chronic Disease. CRC Press. 351.
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Conference Poster (Faculty180)
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Dissertation (Faculty180)
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Early Access (Web of Science)
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2021Progress on siRNA-based gene therapy targeting secondary injury after intracerebral hemorrhage. GENE THERAPY.Full Text via DOI: 10.1038/s41434-021-00304-3 PMID: 34754099
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Editorial Material (Web of Science)
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2022Oxidative stress in chronic and acute CNS insults. NEUROCHEMISTRY INTERNATIONAL.Full Text via DOI: 10.1016/j.neuint.2021.105274 PMID: 34971748
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2015Withania somnifera: a pre-clinical study on neuroregenerative therapy for stroke. NEURAL REGENERATION RESEARCH. 183-185.Full Text via DOI: 10.4103/1673-5374.152362
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Meeting Abstract (Web of Science)
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2021Induction of Inflammation in the Brain by Daily JUUL Aerosol Inhalation. FASEB JOURNAL. fasebj.2021.35.S1.04368.Full Text via DOI: 10.1096/fasebj.2021.35.s1.04368
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2014Flavonoid-glycosides from Rumex aquaticus with neuroprotective activity. PLANTA MEDICA. 1446-1446.
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2012Neuroprotective activities of a common structural motif in neuroprotective natural products. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
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Patent (Faculty180)
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Presentation (Faculty180)
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Proceedings (Faculty180)
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Review Article (Web of Science)
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2022The influence of gut microbiota alteration on age-related neuroinflammation and cognitive decline. NEURAL REGENERATION RESEARCH. 2407-2412.Full Text via DOI: 10.4103/1673-5374.335837 PMID: 35535879
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2022Small interfering RNAs based therapies for intracerebral hemorrhage: challenges and progress in drug delivery systems. NEURAL REGENERATION RESEARCH. 1717-1725.Full Text via DOI: 10.4103/1673-5374.332129 PMID: 35017419
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2021Mechanistic role of boswellic acids in Alzheimer's disease: Emphasis on anti-inflammatory properties. BIOMEDICINE & PHARMACOTHERAPY.Full Text via DOI: 10.1016/j.biopha.2021.112250 PMID: 34607104
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2021Intracerebral Hemorrhage and Diabetes Mellitus: Blood-Brain Barrier Disruption, Pathophysiology, and Cognitive Impairments. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. 312-326.Full Text via DOI: 10.2174/1871527320666210223145112 PMID: 33622232
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2020The role of cofilin in age-related neuroinflammation. NEURAL REGENERATION RESEARCH. 1451-1459.Full Text via DOI: 10.4103/1673-5374.274330 PMID: 31997804
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2017The Interplay between Cofilin and Phospho-Cofilin: Its Role in Maintaining Blood Brain Barrier Integrity. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. 279-290.Full Text via DOI: 10.2174/1871527316666170117115040
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2016Cofilin as a Promising Therapeutic Target for Ischemic and Hemorrhagic Stroke. TRANSLATIONAL STROKE RESEARCH. 33-41.Full Text via DOI: 10.1007/s12975-015-0438-2
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2016Dry Eye Disease: Present Challenges in the Management and Future Trends. CURRENT PHARMACEUTICAL DESIGN. 4470-4490.Full Text via DOI: 10.2174/1381612822666160614012634
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2014Heme Oxygenase 1-Mediated Neurogenesis Is Enhanced by Ginkgo biloba (EGb 761A (R)) After Permanent Ischemic Stroke in Mice. MOLECULAR NEUROBIOLOGY. 945-956.Full Text via DOI: 10.1007/s12035-013-8572-x
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2012Sirtuins in Neurodegenerative Diseases: A Biological-Chemical Perspective. NEURODEGENERATIVE DISEASES. 1-10.Full Text via DOI: 10.1159/000329724
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full name
- Zahoor A. Shah
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Cumulative publications in Scholars@UToledo
research areas
- Agriculture
- Biochemistry & Molecular Biology
- Cell Biology
- Chemistry
- Endocrinology & Metabolism
- Immunology
- Integrative & Complementary Medicine
- Materials Science
- Neurosciences & Neurology
- Nutrition & Dietetics
- Ophthalmology
- Pharmacology & Pharmacy
- Plant Sciences
- Science & Technology - Other Topics
- Toxicology