John Y Jun
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Interim Division Chief, Division of Endocrinology, Diabetes and Metabolism, Department of Medicine
Interim Program Director, Endocrinology Fellowship Training Program, University of Toledo , University of Toledo
Contact Info
Publications
selected publications
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Article (Faculty180)
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2023Aldosterone- and Cortisol Co-secreting Adrenal Cortical Neoplasm With Lipomatous and Myelolipomatous Metaplasia. JCEM case reports. 1:luad012.
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2021Imatinib improves insulin resistance and inhibits injury-induced neointimal hyperplasia in high fat diet-fed mice. European journal of pharmacology. 890:173666.
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2019Locally invasive pheochromocytoma combined with primary malignant adrenal lymphoma. AACE Clinical Case Reports. 5:e124-e128.
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2019Locally invasive pheochromocytoma combined with primary malignant adrenal lymphoma. AACE clinical case reports. 5:e124-e128.
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2016Sulforaphane improves dysregulated metabolic profile and inhibits leptin-induced VSMC proliferation: Implications toward suppression of neointima formation after arterial injury in western diet-fed obese mice. The Journal of nutritional biochemistry. 32:73-84.
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2013Expression of conventional and novel glucose transporters, GLUT1, -9, -10, and -12, in vascular smooth muscle cells. American journal of physiology. Cell physiology. 304:C574-89.
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2012TRPM2 Ca2+ channel regulates energy balance and glucose metabolism. American journal of physiology. Endocrinology and metabolism. 302:E807-16.
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2011PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates. American journal of physiology. Cell physiology. 300:C1375-85.
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2011Spontaneously diabetic Ins2(+/Akita):apoE-deficient mice exhibit exaggerated hypercholesterolemia and atherosclerosis. American journal of physiology. Endocrinology and metabolism. 301:E145-54.
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2010Early hepatic insulin resistance precedes the onset of diabetes in obese C57BLKS-db/db mice. Diabetes. 59:1616-25.
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2009KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity. Cell metabolism. 10:366-78.
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2009Prevention of steatosis by hepatic JNK1. Cell metabolism. 10:491-8.
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2008A stress signaling pathway in adipose tissue regulates hepatic insulin resistance. Science (New York, N.Y.). 322:1539-43.
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2008Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells. Breast cancer research and treatment. 107:33-40.
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2008Medical management of persistent or recurrent differentiated thyroid carcinoma. Otolaryngologic clinics of North America. 41:1241.
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2007Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling. American journal of physiology. Endocrinology and metabolism. 293:E1687-96.
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2000No significant correlation exists between core promoter mutations, viral replication, and liver damage in chronic hepatitis B infection. Hepatology (Baltimore, Md.). 32:1154-62.
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2000Phosphatidylinositol 3-kinase stimulates muscle differentiation by activating p38 mitogen-activated protein kinase. Biochemical and biophysical research communications. 276:502-7.
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Article (Web of Science)
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2021Imatinib improves insulin resistance and inhibits injury-induced neointimal hyperplasia in high fat diet-fed mice. EUROPEAN JOURNAL OF PHARMACOLOGY. 890.Full Text via DOI: 10.1016/j.ejphar.2020.173666 PMID: 33131722
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2016Sulforaphane improves dysregulated metabolic profile and inhibits leptin-induced VSMC proliferation: Implications toward suppression of neointima formation after arterial injury in western diet-fed obese mice. JOURNAL OF NUTRITIONAL BIOCHEMISTRY. 32:73-84.Full Text via DOI: 10.1016/j.jnutbio.2016.01.009
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2013Expression of conventional and novel glucose transporters, GLUT1, -9, -10, and -12, in vascular smooth muscle cells. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 304:C574-C589.Full Text via DOI: 10.1152/ajpcell.00275.2012
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2012Leptin treatment inhibits the progression of atherosclerosis by attenuating hypercholesterolemia in type 1 diabetic Ins2+/Akita:apoE−/− mice. ATHEROSCLEROSIS. 225:341-347.Full Text via DOI: 10.1016/j.atherosclerosis.2012.10.031
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2012TRPM2 Ca2+ channel regulates energy balance and glucose metabolism. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 302:E807-E816.Full Text via DOI: 10.1152/ajpendo.00239.2011
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2011PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 300:C1375-C1385.Full Text via DOI: 10.1152/ajpcell.00670.2008
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2011Spontaneously diabetic Ins2+/Akita:apoE-deficient mice exhibit exaggerated hypercholesterolemia and atherosclerosis. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 301:E145-E154.Full Text via DOI: 10.1152/ajpendo.00034.2011
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2010Grp78 Heterozygosity Promotes Adaptive Unfolded Protein Response and Attenuates Diet-Induced Obesity and Insulin Resistance. DIABETES. 59:6-16.Full Text via DOI: 10.2337/db09-0755
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2010Deficiency of Phosphoinositide 3-Kinase Enhancer Protects Mice From Diet-Induced Obesity and Insulin Resistance. DIABETES. 59:883-893.Full Text via DOI: 10.2337/db09-1404
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2010Early Hepatic Insulin Resistance Precedes the Onset of Diabetes in Obese C57BLKS-db/db Mice. DIABETES. 59:1616-1625.Full Text via DOI: 10.2337/db09-0878
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2009KSR2 Is an Essential Regulator of AMP Kinase, Energy Expenditure, and Insulin Sensitivity. CELL METABOLISM. 10:366-378.Full Text via DOI: 10.1016/j.cmet.2009.09.010
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2009Nutrient Stress Activates Inflammation and Reduces Glucose Metabolism by Suppressing AMP-Activated Protein Kinase in the Heart. DIABETES. 58:2536-2546.Full Text via DOI: 10.2337/db08-1361
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2009Prevention of Steatosis by Hepatic JNK1. CELL METABOLISM. 10:491-498.Full Text via DOI: 10.1016/j.cmet.2009.09.007
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2008A Stress Signaling Pathway in Adipose Tissue Regulates Hepatic Insulin Resistance. SCIENCE. 322:1539-1543.Full Text via DOI: 10.1126/science.1160794
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2008Medical Management of Persistent or Recurrent Differentiated Thyroid Carcinoma. Otolaryngologic Clinics of North America. 41:1241-1260.Full Text via DOI: 10.1016/j.otc.2008.05.005
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2007Effects of polyamine depletion by α-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells. BREAST CANCER RESEARCH AND TREATMENT. 107:33-40.Full Text via DOI: 10.1007/s10549-007-9533-8
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2007Effects of polyamine depletion by α-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells. BREAST CANCER RESEARCH AND TREATMENT. 105:29-36.Full Text via DOI: 10.1007/s10549-006-9432-4
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2007Nonobese, insulin-deficient Ins2Akitamice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 293:E1687-E1696.Full Text via DOI: 10.1152/ajpendo.00256.2007
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Case Study (Faculty180)
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2020Clinical Dilemmas of Adrenal Incidentaloma, Is Change in HU Clinically Significant?. Volume 4, Issue Supplement_1, April.
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Conference Poster (Faculty180)
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Meeting Abstract (Web of Science)
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2015Imatinib attenuates exaggerated intimal hyperplasia after arterial injury and improves glycemic control and lipid profile in high fat diet-fed mice. ATHEROSCLEROSIS. e61.Full Text via DOI: 10.1016/j.atherosclerosis.2015.04.216
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Contact
full name
- John Y Jun
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Cumulative publications in Scholars@UToledo
