Deficiency of phosphoinositide 3-kinase enhancer protects mice from diet-induced obesity and insulin resistance Article (Faculty180)

cited authors

  • Chan, Chi B; Liu, Xia; Jung, Dae Y; Jun, John Y; Luo, Hongbo R; Kim, Jason K; Ye, Keqiang

description

  • Phosphoinositide 3-kinase enhancer A (PIKE-A) is a proto-oncogene that promotes tumor growth and transformation by enhancing Akt activity. However, the physiological functions of PIKE-A in peripheral tissues are unknown. Here, we describe the effect of PIKE deletion in mice and explore the role of PIKE-A in obesity development.

authors

publication date

  • 2010

published in

start page

  • 883

end page

  • 93