Ko, Hwi J; Zhang, Zhiyou; Jung, Dae Y; Jun, John Y; Ma, Zhexi; Jones, K E; Chan, Sook Y; Kim, Jason K
description
Heart failure is a major cause of mortality in diabetes and may be causally associated with altered metabolism. Recent reports indicate a role of inflammation in peripheral insulin resistance, but the impact of inflammation on cardiac metabolism is unknown. We investigated the effects of diet-induced obesity on cardiac inflammation and glucose metabolism in mice.