Article (Faculty180)

• 2024

  37th Annual Meeting of the Ohio Physiological Society: October 6-7, 2023, The University of Toledo, Toledo, Ohio.  Advances in physiology education.  48:547-549.
• 2024

  A TRP to Pathological Angiogenesis and Vascular Normalization.  Comprehensive Physiology.  14:5389-5406.
• 2023

  Angiotensin II induces endothelial dysfunction and vascular remodeling by downregulating TRPV4 channels.  Journal of molecular and cellular cardiology plus.  6.
• 2023

  Deletion of Endothelial TRPV4 Protects Heart From Pressure Overload-Induced Hypertrophy.  Hypertension (Dallas, Tex. : 1979).  80:2345-2356.
• 2018

  AMP-activated kinase "Keaps" ischemia/reperfusion-induced necroptosis under control.  International journal of cardiology.  259:168-169.
• 2017

  Changing the Channels: Nature's Remote Controlling in Health and Disease.  Circulation research.  120:599-601.
• 2017

  Mechanosensitive transient receptor potential vanilloid 4 regulates -induced airway remodeling 2 distinct pathways modulating matrix synthesis and degradation.  FASEB journal : official publication of the Federation of American Societies for Experimental Biology.  31:1556-1570.
• 2016

  4-Hydroxynonenal dependent alteration of TRPV1-mediated coronary microvascular signaling.  Free radical biology & medicine.  101:10-19.
• 2016

  Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy.  Oncogene.  35:314-22.
• 2016

  Differential regulation of TRPV1 channels by H2O2: implications for diabetic microvascular dysfunction.  Basic research in cardiology.  111:21.
• 2016

  Leukotriene D4 and prostaglandin E2 signals synergize and potentiate vascular inflammation in a mast cell-dependent manner through cysteinyl leukotriene receptor 1 and E-prostanoid receptor 3.  The Journal of allergy and clinical immunology.  137:289-298.
• 2016

  TRPV4 channels regulate tumor angiogenesis via modulation of Rho/Rho kinase pathway.  Oncotarget.  7:25849-61.
• 2015

  A bouquet for a broken heart: can flowers repair a damaged heart?.  Circulation research.  116:1729-31.
• 2015

  Modulation of mast cell proliferative and inflammatory responses by leukotriene d4 and stem cell factor signaling interactions.  Journal of cellular physiology.  230:595-602.
• 2015

  TRPV4 channel activation selectively inhibits tumor endothelial cell proliferation.  Scientific reports.  5:14257.
• 2014

  Hyperglycemia enhances function and differentiation of adult rat cardiac fibroblasts.  Canadian journal of physiology and pharmacology.  92:598-604.
• 2014

  TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice.  The Journal of clinical investigation.  124:5225-38.
• 2013

  2.5D constructs for characterizing phase separated polymer blend surface morphology in tissue engineering scaffolds.  Journal of biomedical materials research. Part A.  101:1502-10.
• 2013

  A TRP to cardiac fibroblast differentiation.  Channels (Austin, Tex.).  7:211-4.
• 2013

  Cysteinyl leukotrienes regulate endothelial cell inflammatory and proliferative signals through CysLT₂ and CysLT₁ receptors.  Scientific reports.  3:3274.
• 2013

  Differential regulation of cysteinyl leukotriene receptor signaling by protein kinase C in human mast cells.  PloS one.  8:e71536.
• 2013

  Injury models to study cardiac remodeling in the mouse: myocardial infarction and ischemia-reperfusion.  Methods in molecular biology (Clifton, N.J.).  1037:325-42.
• 2013

  TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals.  Journal of molecular and cellular cardiology.  54:45-52.
• 2012

  Absence of type VI collagen paradoxically improves cardiac function, structure, and remodeling after myocardial infarction.  Circulation research.  110:851-6.
• 2012

  Disruption of TRPV1-mediated coupling of coronary blood flow to cardiac metabolism in diabetic mice: role of nitric oxide and BK channels.  American journal of physiology. Heart and circulatory physiology.  303:H216-23.
• 2012

  Upregulation of thrombospondin-1 expression by leptin in vascular smooth muscle cells via JAK2- and MAPK-dependent pathways.  American journal of physiology. Cell physiology.  303:C179-91.
• 2011

  Endothelin-mediated in vivo pressor responses following TRPV1 activation.  American journal of physiology. Heart and circulatory physiology.  301:H1135-42.
• 2011

  PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells.  American journal of physiology. Heart and circulatory physiology.  301:H757-65.
• 2011

  Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning.  PloS one.  6:e28303.
• 2010

  Actomyosin tension exerted on the nucleus through nesprin-1 connections influences endothelial cell adhesion, migration, and cyclic strain-induced reorientation.  Biophysical journal.  99:115-23.
• 2010

  Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins.  Integrative biology : quantitative biosciences from nano to macro.  2:435-42.
• 2009

  Mechanical control of cAMP signaling through integrins is mediated by the heterotrimeric Galphas protein.  Journal of cellular biochemistry.  106:529-38.
• 2009

  TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling.  Circulation research.  104:1123-30.
• 2008

  Directional control of cell motility through focal adhesion positioning and spatial control of Rac activation.  FASEB journal : official publication of the Federation of American Societies for Experimental Biology.  22:1649-59.
• 2008

  Investigating complexity of protein-protein interactions in focal adhesions.  Biochemical and biophysical research communications.  369:929-34.
• 2008

  Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro.  Proceedings of the National Academy of Sciences of the United States of America.  105:11305-10.
• 2006

  Force meets chemistry: analysis of mechanochemical conversion in focal adhesions using fluorescence recovery after photobleaching.  Journal of cellular biochemistry.  97:1175-83.
• 2005

  ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins.  FEBS letters.  579:5589-95.
• 2005

  Hierarchy of ADAM12 binding to integrins in tumor cells.  Experimental cell research.  309:438-50.
• 2004

  Regulation of ADAM12 cell-surface expression by protein kinase C epsilon.  The Journal of biological chemistry.  279:51601-11.
• 2003

  ADAM12 induces actin cytoskeleton and extracellular matrix reorganization during early adipocyte differentiation by regulating beta1 integrin function.  Journal of cell science.  116:3893-904.
• 2003

  ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA.  The Journal of biological chemistry.  278:9576-84.
• 2002

  Leukotriene D4 induces association of active RhoA with phospholipase C-gamma1 in intestinal epithelial cells.  The Biochemical journal.  365:157-63.
• 2002

  Leukotriene D4-induced calcium signaling in human intestinal epithelial cells.  Advances in experimental medicine and biology.  507:187-91.
• 2001

  The epsilon isoform of protein kinase C is involved in regulation of the LTD(4)-induced calcium signal in human intestinal epithelial cells.  Experimental cell research.  262:95-103.
• 2000

  Differential formation of octadecadienoic acid and octadecatrienoic acid products in control and injured/infected potato tubers.  Biochimica et biophysica acta.  1483:294-300.
• 2000

  Leukotriene D(4) triggers an association between gbetagamma subunits and phospholipase C-gamma1 in intestinal epithelial cells.  The Journal of biological chemistry.  275:9849-53.
• 2000

  Purification and characterization of rat testicular glutathione S-transferases: role in the synthesis of eicosanoids.  Asian journal of andrology.  2:277-82.
• 1998

  Leukotriene D4 induces a rapid increase in cAMP in the human epithelial cell line, Int 407: a potential role for this signal in the regulation of calcium influx through the plasma membrane.  Cell calcium.  24:9-16.
• 1998

  Pulmonary lipid peroxidation and antioxidant defenses during exhaustive physical exercise: the role of vitamin E and selenium.  Nutrition (Burbank, Los Angeles County, Calif.).  14:448-51.
• 1997

  Enhanced production of LTB4 and free radicals in rat lung by exhaustive physical exercise.  Biochemistry and molecular biology international.  41:641-6.
• 1995

  Induction of Ya1 subunit of rat hepatic glutathione S-transferases by exercise-induced oxidative stress.  Archives of biochemistry and biophysics.  323:6-10.
• 1992

  Dietary supplementation of vitamin E protects heart tissue from exercise-induced oxidant stress.  Molecular and cellular biochemistry.  111:109-15.
• 1992

  Exercise-induced oxidant stress in the lung tissue: role of dietary supplementation of vitamin E and selenium.  Biochemistry international.  26:863-71.