Development of bisubstrate analog inhibitors of aspartate N-acetyltransferase, a critical brain enzyme

Article (Web of Science)

• cited authors: Mutthamsetty, Vinay; Dahal, Gopal P.; Wang, Qinzhe; Viola, Ronald E.
• publication date: November 20, 2019
• webpage: Web of Science
• published in: CHEMICAL BIOLOGY & DRUG DESIGN Journal
• category: CHEMISTRY, MEDICINAL Category

keywords

• Canavan disease
• aspartate N-acetyltransferase
• bisubstrate analogs
• drug design
• enzyme mechanism

• start page: 48
• end page: 57
• volume: 95
• issue: 1