William Scott Crawley
- Associate Professor of Biological Sciences, Biological Sciences , College of Natural Sciences and Mathematics
Contact Info
Publications
selected publications
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Article (Web of Science)
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2020A cryptic sequence targets the adhesion complex scaffold ANKS4B to apical microvilli to promote enterocyte brush border assembly. JOURNAL OF BIOLOGICAL CHEMISTRY. 295:12588-12604.Full Text via DOI: 10.1074/jbc.ra120.013790
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2020A heterologous in-cell assay for investigating intermicrovillar adhesion complex interactions reveals a novel protrusion length-matching mechanism. JOURNAL OF BIOLOGICAL CHEMISTRY. 295:16191-16206.Full Text via DOI: 10.1074/jbc.ra120.015929
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2020The small EF-hand protein CALML4 functions as a critical myosin light chain within the intermicrovillar adhesion complex. JOURNAL OF BIOLOGICAL CHEMISTRY. 295:9281-9296.Full Text via DOI: 10.1074/jbc.ra120.012820
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2018Muscle-specific stress fibers give rise to sarcomeres in cardiomyocytes. ELIFE. 7.Full Text via DOI: 10.7554/elife.42144
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2017Shear stress induces noncanonical autophagy in intestinal epithelial monolayers. MOLECULAR BIOLOGY OF THE CELL. 28:3043-3056.Full Text via DOI: 10.1091/mbc.e17-01-0021
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2016ANKS4B Is Essential for Intermicrovillar Adhesion Complex Formation. DEVELOPMENTAL CELL. 36:190-200.Full Text via DOI: 10.1016/j.devcel.2015.12.022
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2016Impact of cordon-bleu expression on actin cytoskeleton architecture and dynamics. CYTOSKELETON. 73:670-679.Full Text via DOI: 10.1002/cm.21317
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2016Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex. CURRENT BIOLOGY. 26:2717-2728.Full Text via DOI: 10.1016/j.cub.2016.08.014
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2016Structure of the Dictyostelium Myosin-II Heavy Chain Kinase A (MHCK-A) α-kinase domain apoenzyme reveals a novel autoinhibited conformation. SCIENTIFIC REPORTS. 6:26634.Full Text via DOI: 10.1038/srep26634
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2016Structure of the Single-lobe Myosin Light Chain C in Complex with the Light Chain-binding Domains of Myosin-1C Provides Insights into Divergent IQ Motif Recognition. JOURNAL OF BIOLOGICAL CHEMISTRY. 291:19607-19617.Full Text via DOI: 10.1074/jbc.m116.746313
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2015Cordon bleu promotes the assembly of brush border microvilli. MOLECULAR BIOLOGY OF THE CELL. 26:3803-3815.Full Text via DOI: 10.1091/mbc.e15-06-0443
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2014Dynamics of brush border remodeling induced by enteropathogenicE. coli. GUT MICROBES. 5:504-516.Full Text via DOI: 10.4161/gmic.32084
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2014Intestinal Brush Border Assembly Driven by Protocadherin-Based Intermicrovillar Adhesion. CELL. 157:433-446.Full Text via DOI: 10.1016/j.cell.2014.01.067
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2014Shaping the intestinal brush border. JOURNAL OF CELL BIOLOGY. 207:441-451.Full Text via DOI: 10.1083/jcb.201407015
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2014Structure of the Small Dictyostelium discoideum Myosin Light Chain MlcB Provides Insights into MyoB IQ Motif Recognition. JOURNAL OF BIOLOGICAL CHEMISTRY. 289:17030-17042.Full Text via DOI: 10.1074/jbc.m113.536532
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2013PakB binds to the SH3 domain of Dictyostelium Abp1 and regulates its effects on cell polarity and early development. MOLECULAR BIOLOGY OF THE CELL. 24:2216-2227.Full Text via DOI: 10.1091/mbc.e12-12-0883
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2011Autophosphorylation Activates Dictyostelium Myosin II Heavy Chain Kinase A by Providing a Ligand for an Allosteric Binding Site in the α-Kinase Domain. JOURNAL OF BIOLOGICAL CHEMISTRY. 286:2607-2616.Full Text via DOI: 10.1074/jbc.m110.177014
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2011Identification of Calmodulin and MlcC as Light Chains forDictyosteliumMyosin-I Isozymes. BIOCHEMISTRY. 50:6579-6588.Full Text via DOI: 10.1021/bi2007178
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2010A Myosin IK-Abp1-PakB Circuit Acts as a Switch to Regulate Phagocytosis Efficiency. MOLECULAR BIOLOGY OF THE CELL. 21:1505-1518.Full Text via DOI: 10.1091/mbc.e09-06-0485
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2010Crystal Structure of the α-Kinase Domain of Dictyostelium Myosin Heavy Chain Kinase A. SCIENCE SIGNALING. 3.Full Text via DOI: 10.1126/scisignal.2000525
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2009Identification of dimer interactions required for the catalytic activity of the TRPM7 alpha-kinase domain. BIOCHEMICAL JOURNAL. 420:115-122.Full Text via DOI: 10.1042/bj20081405
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2008Compartmentation and compartment-specific regulation of PDE5 by protein kinase G allows selective cGMP-mediated regulation of platelet functions. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 105:13650-13655.Full Text via DOI: 10.1073/pnas.0804738105
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2008Determinants for substrate phosphorylation by Dictyostelium myosin II heavy chain kinases A and B and eukaryotic elongation factor-2 kinase. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1784:908-915.Full Text via DOI: 10.1016/j.bbapap.2008.03.001
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2007Formation of Extracellular Matrix-Digesting Invadopodia by Primary Aortic Smooth Muscle Cells. CIRCULATION RESEARCH. 100:1328-1336.Full Text via DOI: 10.1161/circresaha.106.147744
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2006Identification and Characterization of an 8-kDa Light Chain Associated with Dictyostelium discoideum MyoB, a Class I Myosin. JOURNAL OF BIOLOGICAL CHEMISTRY. 281:6307-6315.Full Text via DOI: 10.1074/jbc.m508670200
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2005PAK1 induces podosome formation in A7r5 vascular smooth muscle cells in a PAK-interacting exchange factor-dependent manner. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 289:C898-C907.Full Text via DOI: 10.1152/ajpcell.00095.2005
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2001Specific Phosphorylation of Threonine by theDictyostelium Myosin II Heavy Chain Kinase Family. JOURNAL OF BIOLOGICAL CHEMISTRY. 276:17836-17843.Full Text via DOI: 10.1074/jbc.m009366200
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1980Yields and Composition of Edible and Inedible By-Products of Broilers Processed at 6, 7, and 8 Weeks of Age. Poultry Science. 59:2243-2246.Full Text via DOI: 10.3382/ps.0592243
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- William Scott Crawley
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Cumulative publications in Scholars@UToledo