Article (Faculty180)

• 2025

  Heparan Sulfate-Based Neoproteoglycan for Targeted Lysosomal Degradation of Amyloid-β

  .  Journal of medicinal chemistry.  68:11979-11989.
• 2025

  Single cell profiling of human airway identifies tuft-ionocyte progenitor cells displaying cytokine-dependent differentiation bias in vitro.  Nature communications.  16:5180.
• 2025

  WSTF nuclear autophagy regulates chronic but not acute inflammation.  Nature. 
• 2024

  Immunogenic Sulfated l-Idose Homo Oligosaccharides Elicit Neutralizing Antibody against Native Heparan Sulfate with Biomarker and Therapeutic Possibilities

  .  Journal of medicinal chemistry.  67:18465-18477.
• 2024

  NeoMProbe: a new class of fluorescent cellular and tissue membrane probe

  .  Chemical science.  15:19962-19969.
• 2023

  Protocol for Bulk-ATAC sequencing in head and neck squamous cell carcinoma

  .  STAR protocols.  4:102233.
• 2023

  A deep lung cell atlas reveals cytokine-mediated lineage switching of a rare cell progenitor of the human airway epithelium.  bioRxiv : the preprint server for biology. 
• 2023

  Reprogramming by drug-like molecules leads to regeneration of cochlear hair cell-like cells in adult mice.  Proceedings of the National Academy of Sciences of the United States of America.  120:e2215253120.
• 2023

  Targeting ITGB4/SOX2-driven lung cancer stem cells using proteasome inhibitors.  iScience.  26:107302.
• 2023

  The long non-coding RNA TAZ-AS202 promotes lung cancer progression via regulation of the E2F1 transcription factor and activation of Ephrin signaling.  Cell death & disease.  14:752.
• 2022

  Current and Future Biomarkers for Immune Checkpoint Inhibitors in Head and Neck Squamous Cell Carcinoma

  .  Current oncology (Toronto, Ont.).  29:4185-4198.
• 2022

  Molecular Biomarkers of Malignant Transformation in Head and Neck Dysplasia

  .  Cancers.  14.
• 2022

  YAP1 maintains active chromatin state in head and neck squamous cell carcinomas that promotes tumorigenesis through cooperation with BRD4

  .  Cell reports.  39:110970.
• 2022

  First Clinical Results of Fluorescence Lifetime-enhanced Tumor Imaging Using Receptor-targeted Fluorescent Probes.  Clinical cancer research : an official journal of the American Association for Cancer Research.  28:2373-2384.
• 2021

  A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma.  Nature metabolism.  3:182-195.
• 2021

  Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM).  British journal of cancer.  125:582-592.
• 2021

  Novel Therapeutic Targets and Immune Dysfunction in Malignant Pleural Mesothelioma.  Frontiers in pharmacology.  12:806570.
• 2021

  RASAL2 Confers Collateral MEK/EGFR Dependency in Chemoresistant Triple-Negative Breast Cancer.  Clinical cancer research : an official journal of the American Association for Cancer Research.  27:4883-4897.
• 2020

  RUVBL1 is an amplified epigenetic factor promoting proliferation and inhibiting differentiation program in head and neck squamous cancers

  .  Oral oncology.  111:104930.
• 2020

  Aneuploidy and a deregulated DNA damage response suggest haploinsufficiency in breast tissues of mutation carriers.  Science advances.  6:eaay2611.
• 2020

  Inhibitors of the Transcription Factor STAT3 Decrease Growth and Induce Immune Response Genes in Models of Malignant Pleural Mesothelioma (MPM).  Cancers.  13.
• 2019

  BAF60A mediates interactions between the microphthalmia-associated transcription factor and the BRG1-containing SWI/SNF complex during melanocyte differentiation.  Journal of cellular physiology.  234:11780-11791.
• 2018

  Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity.  Developmental cell.  44:679-693.e5.
• 2018

  Expressed Gene Fusions as Frequent Drivers of Poor Outcomes in Hormone Receptor-Positive Breast Cancer.  Cancer discovery.  8:336-353.
• 2017

  ACTL6A Is Co-Amplified with p63 in Squamous Cell Carcinoma to Drive YAP Activation, Regenerative Proliferation, and Poor Prognosis

  .  Cancer cell.  31:35-49.
• 2014

  Basal cell signaling by p63 controls luminal progenitor function and lactation via NRG1.  Developmental cell.  28:147-60.
• 2014

  Modulation of Brahma expression by the mitogen-activated protein kinase/extracellular signal regulated kinase pathway is associated with changes in melanoma proliferation.  Archives of biochemistry and biophysics.  563:125-35.
• 2014

  Yap tunes airway epithelial size and architecture by regulating the identity, maintenance, and self-renewal of stem cells.  Developmental cell.  30:151-65.
• 2012

  A Micro-RNA Connection in BRaf(V600E)-Mediated Premature Senescence of Human Melanocytes.  International journal of cell biology.  2012:913242.
• 2010

  Modulation of extracellular matrix/adhesion molecule expression by BRG1 is associated with increased melanoma invasiveness

  .  MOLECULAR CANCER. 
• 2010

  SWItching on the transcriptional circuitry in melanoma.  Epigenetics.  5:469-75.
• 2003

  A non-canonical transferable signal mediates nuclear import of simian immunodeficiency virus Vpx protein.  Journal of molecular biology.  331:1141-56.
• 2003

  Genomic instability and tumor-specific alterations in oral squamous cell carcinomas assessed by inter-(simple sequence repeat) PCR.  Clinical cancer research : an official journal of the American Association for Cancer Research.  9:1057-62.
• ATP Dependent Chromatin Remodeling Enzymes in Embryonic Stem Cells.  STEM CELL REVIEWS AND REPORTS. 
• BRG1 promotes survival of UV-irradiated melanoma cells by cooperating with MITF to activate the melanoma inhibitor of apoptosis gene.  PIGMENT CELL & MELANOMA RESEARCH. 
• Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma.  ONCOGENE.