Smith, Robert E

Robert E Smith
Close

Positions

Neurosciences , College of Medicine and Life Sciences

Contact Info

ROBERT.MCCULLUMSMITH@UTOLEDO.EDU

selected publications

Article (Faculty180)
- 2020
  
  Consequences of NMDA receptor deficiency can be rescued in the adult brain. Molecular psychiatry.
- 2020
  
  KEOPS complex expression in the frontal cortex in major depression and schizophrenia. World Journal of Biological Psychiatry.
Article (Web of Science)
- 2022
  
  Altered purinergic receptor expression in the frontal cortex in schizophrenia. SCHIZOPHRENIA. 8.
  Full Text via DOI: 10.1038/s41537-022-00312-1 PMID: 36376358
- 2022
  
  A bioinformatic inquiry of the EAAT2 interactome in postmortem and neuropsychiatric datasets. SCHIZOPHRENIA RESEARCH. 249:38-46.
  Full Text via DOI: 10.1016/j.schres.2020.03.018 PMID: 32197935
- 2022
  
  A role for endothelial NMDA receptors in the pathophysiology of schizophrenia. SCHIZOPHRENIA RESEARCH. 249:63-73.
  Full Text via DOI: 10.1016/j.schres.2020.10.004 PMID: 33189520
- 2022
  
  Subcellular partitioning of protein kinase activity revealed by functional kinome profiling. SCIENTIFIC REPORTS. 12.
  Full Text via DOI: 10.1038/s41598-022-21026-5 PMID: 36243751
- 2022
  
  Antipsychotics impair regulation of glucose metabolism by central glucose. MOLECULAR PSYCHIATRY. 27:4741-4753.
  Full Text via DOI: 10.1038/s41380-022-01798-y PMID: 36241692
- 2022
  
  Gene Enrichment Analysis of Astrocyte Subtypes in Psychiatric Disorders and Psychotropic Medication Datasets. CELLS. 11.
  Full Text via DOI: 10.3390/cells11203315 PMID: 36291180
- 2022
  
  Identification of activity-induced Egr3-dependent genes reveals genes associated with DNA damage response and schizophrenia. TRANSLATIONAL PSYCHIATRY. 12.
  Full Text via DOI: 10.1038/s41398-022-02069-8 PMID: 35941129
- 2022
  
  Differential vulnerability of anterior cingulate cortex cell types to diseases and drugs. MOLECULAR PSYCHIATRY.
  Full Text via DOI: 10.1038/s41380-022-01657-w PMID: 35754044
- 2022
  
  Differential genetic associations and expression of PAPST1/SLC35B2 in bipolar disorder and schizophrenia. JOURNAL OF NEURAL TRANSMISSION.
  Full Text via DOI: 10.1007/s00702-022-02503-7 PMID: 35501530
- 2022
  
  Hepatic kinome atlas: An in-depth identification of kinase pathways in liver fibrosis of humans and rodents. HEPATOLOGY.
  Full Text via DOI: 10.1002/hep.32467 PMID: 35313030
- 2022
  
  Assessing the effects of antipsychotic medications on schizophrenia functional analysis: a postmortem proteome study. NEUROPSYCHOPHARMACOLOGY.
  Full Text via DOI: 10.1038/s41386-022-01310-8 PMID: 35354897
- 2022
  
  The active kinome: The modern view of how active protein kinase networks fit in biological research. CURRENT OPINION IN PHARMACOLOGY. 62:117-129.
  Full Text via DOI: 10.1016/j.coph.2021.11.007 PMID: 34968947
- 2021
  
  KRSA: An R package and R Shiny web application for an end-to-end upstream kinase analysis of kinome array data. PLOS ONE. 16.
  Full Text via DOI: 10.1371/journal.pone.0260440 PMID: 34919543
- 2021
  
  Molecular characterization of depression trait and state. MOLECULAR PSYCHIATRY.
  Full Text via DOI: 10.1038/s41380-021-01347-z PMID: 34686766
- 2021
  
  Cellular, molecular, and therapeutic characterization of pilocarpine-induced temporal lobe epilepsy. SCIENTIFIC REPORTS. 11.
  Full Text via DOI: 10.1038/s41598-021-98534-3 PMID: 34580351
- 2021
  
  Microcystin-LR (MC-LR) Triggers Inflammatory Responses in Macrophages. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 22.
  Full Text via DOI: 10.3390/ijms22189939 PMID: 34576099
- 2021
  
  Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity. MOLECULAR PSYCHIATRY.
  Full Text via DOI: 10.1038/s41380-021-01205-y PMID: 34272489
- 2021
  
  Deficits in pattern separation and dentate gyrus proliferation after rodent lateral fluid percussion injury. IBRO NEUROSCIENCE REPORTS. 10:31-41.
  Full Text via DOI: 10.1016/j.ibneur.2020.11.005 PMID: 33861814
- 2021
  
  Fluoxetine as an anti-inflammatory therapy in SARS-CoV-2 infection. BIOMEDICINE & PHARMACOTHERAPY. 138.
  Full Text via DOI: 10.1016/j.biopha.2021.111437 PMID: 33691249
- 2021
  
  mTOR kinase activity disrupts a phosphorylation signaling network in schizophrenia brain. MOLECULAR PSYCHIATRY.
  Full Text via DOI: 10.1038/s41380-021-01135-9 PMID: 33990769
- 2021
  
  Activation of acid-sensing ion channels by carbon dioxide regulates amygdala synaptic protein degradation in memory reconsolidation. MOLECULAR BRAIN. 14.
  Full Text via DOI: 10.1186/s13041-021-00786-7 PMID: 33962650
- 2021
  
  Identification of candidate repurposable drugs to combat COVID-19 using a signature-based approach. SCIENTIFIC REPORTS. 11.
  Full Text via DOI: 10.1038/s41598-021-84044-9 PMID: 33627767
- 2021
  
  Using protein turnover to expand the applications of transcriptomics. SCIENTIFIC REPORTS. 11.
  Full Text via DOI: 10.1038/s41598-021-83886-7 PMID: 33623108
- 2021
  
  Similarities and dissimilarities between psychiatric cluster disorders. MOLECULAR PSYCHIATRY.
  Full Text via DOI: 10.1038/s41380-021-01030-3 PMID: 33504954
- 2021
  
  Role of Astrocytes in Major Neuropsychiatric Disorders. NEUROCHEMICAL RESEARCH.
  Full Text via DOI: 10.1007/s11064-020-03212-x PMID: 33411227
- 2020
  
  Kinome Array Profiling of Patient-Derived Pancreatic Ductal Adenocarcinoma Identifies Differentially Active Protein Tyrosine Kinases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 21.
  Full Text via DOI: 10.3390/ijms21228679 PMID: 33213062
- 2020
  
  KEOPS complex expression in the frontal cortex in major depression and schizophrenia. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY.
  Full Text via DOI: 10.1080/15622975.2020.1821917 PMID: 32914678
- 2020
  
  Combining Neurobehavioral Analysis and In Vivo Photoaffinity Labeling to Understand Protein Targets of Methamphetamine in Casper Zebrafish. ACS CHEMICAL NEUROSCIENCE. 11:2761-2773.
  Full Text via DOI: 10.1021/acschemneuro.0c00416 PMID: 32786314
- 2020
  
  Oxytocin's anti-inflammatory and proimmune functions in COVID-19: a transcriptomic signature-based approach. PHYSIOLOGICAL GENOMICS. 52:401-407.
  Full Text via DOI: 10.1152/physiolgenomics.00095.2020 PMID: 32809918
- 2020
  
  Consequences of NMDA receptor deficiency can be rescued in the adult brain. MOLECULAR PSYCHIATRY.
  Full Text via DOI: 10.1038/s41380-020-00859-4 PMID: 32807843
- 2020
  
  Corticostriatal dysfunction and social interaction deficits in mice lacking the cystine/glutamate antiporter. MOLECULAR PSYCHIATRY.
  Full Text via DOI: 10.1038/s41380-020-0751-3 PMID: 32366950
- 2020
  
  Adenosine Kinase Expression in the Frontal Cortex in Schizophrenia. SCHIZOPHRENIA BULLETIN. 46:690-698.
  Full Text via DOI: 10.1093/schbul/sbz086 PMID: 32275755
- 2020
  
  Protein expression of prenyltransferase subunits in postmortem schizophrenia dorsolateral prefrontal cortex. TRANSLATIONAL PSYCHIATRY. 10.
  Full Text via DOI: 10.1038/s41398-019-0610-7 PMID: 32066669
- 2020
  
  Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator–activated receptor α. JOURNAL OF BIOLOGICAL CHEMISTRY. 295:9804-9822.
  Full Text via DOI: 10.1074/jbc.ra120.013700
- 2019
  
  Neuronal impact of patient-specific aberrant NRXN1 alpha splicing. NATURE GENETICS. 51:1679-+.
  Full Text via DOI: 10.1038/s41588-019-0539-z PMID: 31784728
- 2019
  
  Synergistic effects of common schizophrenia risk variants. NATURE GENETICS. 51:1475-+.
  Full Text via DOI: 10.1038/s41588-019-0497-5 PMID: 31548722
- 2019
  
  Connectivity Analyses of Bioenergetic Changes in Schizophrenia: Identification of Novel Treatments. MOLECULAR NEUROBIOLOGY. 56:4492-4517.
  Full Text via DOI: 10.1007/s12035-018-1390-4 PMID: 30338483
- 2019
  
  Kinase network dysregulation in a human induced pluripotent stem cell model of DISC1 schizophrenia. MOLECULAR OMICS. 15:173-188.
  Full Text via DOI: 10.1039/c8mo00173a PMID: 31106784
- 2019
  
  RNA sequencing in human HepG2 hepatocytes reveals PPAR-alpha mediates transcriptome responsiveness of bilirubin. PHYSIOLOGICAL GENOMICS. 51:234-240.
  Full Text via DOI: 10.1152/physiolgenomics.00028.2019 PMID: 31074682
- 2019
  
  Measurement of lactate levels in postmortem brain, iPSCs, and animal models of schizophrenia. SCIENTIFIC REPORTS. 9.
  Full Text via DOI: 10.1038/s41598-019-41572-9 PMID: 30911039
- 2019
  
  Chronic Dysregulation of Cortical and Subcortical Metabolism After Experimental Traumatic Brain Injury. MOLECULAR NEUROBIOLOGY. 56:2908-2921.
  Full Text via DOI: 10.1007/s12035-018-1276-5
- 2019
  
  Neuron-specific deficits of bioenergetic processes in the dorsolateral prefrontal cortex in schizophrenia. MOLECULAR PSYCHIATRY. 24:1319-1328.
  Full Text via DOI: 10.1038/s41380-018-0035-3
- 2018
  
  Cell-subtype-specific changes in adenosine pathways in schizophrenia. NEUROPSYCHOPHARMACOLOGY. 43:1667-1674.
  Full Text via DOI: 10.1038/s41386-018-0028-6
- 2018
  
  Sex differences in DEK expression in the anterior cingulate cortex and its association with dementia severity in schizophrenia. Schizophrenia Research. 202:188-194.
  Full Text via DOI: 10.1016/j.schres.2018.07.010
- 2017
  
  Abnormalities of signal transduction networks in chronic schizophrenia. npj Schizophrenia. 3:30.
  Full Text via DOI: 10.1038/s41537-017-0032-6
- 2017
  
  Contrasting the Role of xCT and GLT-1 Upregulation in the Ability of Ceftriaxone to Attenuate the Cue-Induced Reinstatement of Cocaine Seeking and Normalize AMPA Receptor Subunit Expression. JOURNAL OF NEUROSCIENCE. 37:5809-5821.
  Full Text via DOI: 10.1523/jneurosci.3717-16.2017
- 2017
  
  Postsynaptic Density-95 Isoform Abnormalities in Schizophrenia. SCHIZOPHRENIA BULLETIN. sbw173.
  Full Text via DOI: 10.1093/schbul/sbw173
- 2017
  
  Traumatic Brain Injury Induces Alterations in Cortical Glutamate Uptake without a Reduction in Glutamate Transporter-1 Protein Expression. JOURNAL OF NEUROTRAUMA. 34:220-234.
  Full Text via DOI: 10.1089/neu.2015.4372
- 2016
  
  Cell-specific abnormalities of glutamate transporters in schizophrenia: sick astrocytes and compensating relay neurons?. MOLECULAR PSYCHIATRY. 21:823-830.
  Full Text via DOI: 10.1038/mp.2015.148
- 2016
  
  Changes in cortical N-methyl-d-aspartate receptors and post-synaptic density protein 95 in schizophrenia, mood disorders and suicide. AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY. 50:275-283.
  Full Text via DOI: 10.1177/0004867415586601
- 2016
  
  Cortical PGC-1α-Dependent Transcripts Are Reduced in Postmortem Tissue From Patients With Schizophrenia. SCHIZOPHRENIA BULLETIN. 42:1009-1017.
  Full Text via DOI: 10.1093/schbul/sbv184
- 2016
  
  Decreased protein S-palmitoylation in dorsolateral prefrontal cortex in schizophrenia. Schizophrenia Research. 177:78-87.
  Full Text via DOI: 10.1016/j.schres.2016.01.054
- 2016
  
  Systematic evaluation of data-independent acquisition for sensitive and reproducible proteomics-a prototype design for a single injection assay. JOURNAL OF MASS SPECTROMETRY. 51:1-11.
  Full Text via DOI: 10.1002/jms.3716
- 2016
  
  Tyrosine hydroxylase localization in the nucleus accumbens in schizophrenia. Brain Structure and Function. 221:4451-4458.
  Full Text via DOI: 10.1007/s00429-015-1174-9
- 2015
  
  Decreased Chloride Channel Expression in the Dorsolateral Prefrontal Cortex in Schizophrenia. PLOS ONE. 10:e0123158.
  Full Text via DOI: 10.1371/journal.pone.0123158
- 2015
  
  Glutamate transporter splice variant expression in an enriched pyramidal cell population in schizophrenia. TRANSLATIONAL PSYCHIATRY. 5:e579-e579.
  Full Text via DOI: 10.1038/tp.2015.74
- 2015
  
  Purinergic Signaling and Energy Homeostasis in Psychiatric Disorders. CURRENT MOLECULAR MEDICINE. 15:275-295.
  Full Text via DOI: 10.2174/1566524015666150330163724
- 2014
  
  Abnormal partitioning of hexokinase 1 suggests disruption of a glutamate transport protein complex in schizophrenia. Schizophrenia Research. 154:1-13.
  Full Text via DOI: 10.1016/j.schres.2014.01.028
- 2014
  
  Altered serine/threonine kinase activity in schizophrenia. BRAIN RESEARCH. 1568:42-54.
  Full Text via DOI: 10.1016/j.brainres.2014.04.029
- 2014
  
  Global signaling effects of a schizophrenia-associated missense mutation in neuregulin 1: an exploratory study using whole genome and novel kinome approaches. JOURNAL OF NEURAL TRANSMISSION. 121:479-490.
  Full Text via DOI: 10.1007/s00702-013-1142-6
- 2014
  
  Increased G protein-coupled receptor kinase (GRK) expression in the anterior cingulate cortex in schizophrenia. Schizophrenia Research. 159:130-135.
  Full Text via DOI: 10.1016/j.schres.2014.07.040
- 2014
  
  Localization of excitatory amino acid transporters EAAT1 and EAAT2 in human postmortem cortex: A light and electron microscopic study. NEUROSCIENCE. 277:522-540.
  Full Text via DOI: 10.1016/j.neuroscience.2014.07.019
- 2013
  
  Abnormal N-linked glycosylation of cortical AMPA receptor subunits in schizophrenia. Schizophrenia Research. 146:177-183.
  Full Text via DOI: 10.1016/j.schres.2013.01.031
- 2013
  
  Abnormal expression of glutamate transporters in temporal lobe areas in elderly patients with schizophrenia. Schizophrenia Research. 144:1-8.
  Full Text via DOI: 10.1016/j.schres.2012.12.019
- 2013
  
  Gene expression of glutamate metabolizing enzymes in the hippocampal formation in human temporal lobe epilepsy. EPILEPSIA. 54:228-238.
  Full Text via DOI: 10.1111/epi.12008
- 2012
  
  Abnormal Activity of the MAPK- and cAMP-Associated Signaling Pathways in Frontal Cortical Areas in Postmortem Brain in Schizophrenia. NEUROPSYCHOPHARMACOLOGY. 37:896-905.
  Full Text via DOI: 10.1038/npp.2011.267
- 2012
  
  Ampa Receptor Subunit Expression in the Endoplasmic Reticulum in Frontal Cortex of Elderly Patients with Schizophrenia. PLOS ONE. 7:e39190.
  Full Text via DOI: 10.1371/journal.pone.0039190
- 2012
  
  Expression of equilibrative nucleoside transporter type 1 protein in elderly patients with schizophrenia. Neuroreport. 23:224-227.
  Full Text via DOI: 10.1097/wnr.0b013e3283500987
- 2012
  
  Recent advances in targeting the ionotropic glutamate receptors in treating schizophrenia.. CURRENT PHARMACEUTICAL BIOTECHNOLOGY. 13:1535-42.
  Full Text via DOI: 10.2174/138920112800784899 PMID: 22283761
- 2012
  
  Regional differences in expression of β-tubulin isoforms in schizophrenia. Schizophrenia Research. 135:181-186.
  Full Text via DOI: 10.1016/j.schres.2011.12.010
- 2011
  
  Endosomal trafficking of AMPA receptors in frontal cortex of elderly patients with schizophrenia. Schizophrenia Research. 130:260-265.
  Full Text via DOI: 10.1016/j.schres.2011.04.029
- 2011
  
  Glutamatergic Gene Expression Is Specifically Reduced in Thalamocortical Projecting Relay Neurons in Schizophrenia. BIOLOGICAL PSYCHIATRY. 70:646-654.
  Full Text via DOI: 10.1016/j.biopsych.2011.02.022
- 2011
  
  Novel Approaches to the Study of Postmortem Brain in Psychiatric Illness: Old Limitations and New Challenges. BIOLOGICAL PSYCHIATRY. 69:127-133.
  Full Text via DOI: 10.1016/j.biopsych.2010.09.035
- 2010
  
  Abnormal glycosylation of EAAT1 and EAAT2 in prefrontal cortex of elderly patients with schizophrenia. Schizophrenia Research. 117:92-98.
  Full Text via DOI: 10.1016/j.schres.2009.07.025
- 2010
  
  Evidence for Abnormal Forward Trafficking of AMPA Receptors in Frontal Cortex of Elderly Patients with Schizophrenia. NEUROPSYCHOPHARMACOLOGY. 35:2110-2119.
  Full Text via DOI: 10.1038/npp.2010.87
- 2009
  
  Decreased expression of NMDA receptor-associated proteins in frontal cortex of elderly patients with schizophrenia. Neuroreport. 20:1019-1022.
  Full Text via DOI: 10.1097/wnr.0b013e32832d30d9
- 2009
  
  Expression of four housekeeping proteins in elderly patients with schizophrenia. JOURNAL OF NEURAL TRANSMISSION. 116:487-491.
  Full Text via DOI: 10.1007/s00702-008-0143-3
- 2008
  
  Abnormal expression of glutamate transporter and transporter interacting molecules in prefrontal cortex in elderly patients with schizophrenia. Schizophrenia Research. 104:108-120.
  Full Text via DOI: 10.1016/j.schres.2008.06.012
- 2008
  
  Altered Vesicular Glutamate Transporter Expression in the Anterior Cingulate Cortex in Schizophrenia. BIOLOGICAL PSYCHIATRY. 63:766-775.
  Full Text via DOI: 10.1016/j.biopsych.2007.10.020
- 2008
  
  Cortical expression of glial fibrillary acidic protein and glutamine synthetase is decreased in schizophrenia. Schizophrenia Research. 103:71-82.
  Full Text via DOI: 10.1016/j.schres.2008.04.032
- 2007
  
  Decreased NR1, NR2A, and SAP102 transcript expression in the hippocampus in bipolar disorder. BRAIN RESEARCH. 1127:108-118.
  Full Text via DOI: 10.1016/j.brainres.2006.09.011
- 2007
  
  Expression of transcripts for myelination-related genes in the anterior cingulate cortex in schizophrenia☆. Schizophrenia Research. 90:15-27.
  Full Text via DOI: 10.1016/j.schres.2006.11.017
- 2006
  
  Expression of excitatory amino acid transporter interacting protein transcripts in the thalamus in schizophrenia. SYNAPSE. 59:394-402.
  Full Text via DOI: 10.1002/syn.20250
- 2005
  
  Increased expression of glutaminase and glutamine synthetase mRNA in the thalamus in schizophrenia. Schizophrenia Research. 75:27-34.
  Full Text via DOI: 10.1016/j.schres.2004.12.012
- 2005
  
  Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia. SYNAPSE. 57:123-131.
  Full Text via DOI: 10.1002/syn.20164
- 2004
  
  Effects of 6-cyano-7-nitroquinoxaline-2,3-dione on nicotinic receptor subunit transcript expression in the rat brain. SYNAPSE. 52:62-72.
  Full Text via DOI: 10.1002/syn.20003
- 2004
  
  Schizophrenia as a disorder of neuroplasticity.. ANIMAL MODELS FOR MEDICATIONS SCREENING TO TREAT ADDICTION. 59:19-45.
  Full Text via DOI: 10.1016/s0074-7742(04)59002-5 PMID: 15006483
- 2003
  
  CC-chemokine receptor 2 required for bleomycin-induced pulmonary fibrosis. CYTOKINE. 24:266-276.
  Full Text via DOI: 10.1016/j.cyto.2003.08.003
- 2003
  
  Differential effects of antipsychotics on haloperidol-induced vacuous chewing movements and subcortical gene expression in the rat. EUROPEAN JOURNAL OF PHARMACOLOGY. 477:101-112.
  Full Text via DOI: 10.1016/j.ejphar.2003.08.018
- 2003
  
  Expression of ARHGEF11 mRNA in Schizophrenic Thalamus. SKELETAL BIOLOGY AND MEDICINE. 1003:375-377.
  Full Text via DOI: 10.1196/annals.1300.030
- 2003
  
  Expression of Transcripts for the Vesicular Glutamate Transporters in the Human Medial Temporal Lobe. SKELETAL BIOLOGY AND MEDICINE. 1003:438-442.
  Full Text via DOI: 10.1196/annals.1300.046
- 2003
  
  Molecular Abnormalities of the Glutamate Synapse in the Thalamus in Schizophrenia. SKELETAL BIOLOGY AND MEDICINE. 1003:75-93.
  Full Text via DOI: 10.1196/annals.1300.005
- 2002
  
  Striatal Excitatory Amino Acid Transporter Transcript Expression in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder. NEUROPSYCHOPHARMACOLOGY. 26:368-375.
  Full Text via DOI: 10.1016/s0893-133x(01)00370-0
Book Chapter (Web of Science)
- 2009
  
  Alterations of Neurotransmitter Receptors in Schizophrenia: Evidence from Postmortem Studies. Handbook of Neurochemistry and Molecular Neurobiology. 443-492.
  Full Text via DOI: 10.1007/978-0-387-30410-6_14
Conference Poster (Faculty180)
- 2023
  
  Developmental exposure to pyrethroid pesticide causes an autism-related phenotype in mouse and prairie vole
Correction (Web of Science)
- 2015
  
  Erratum: Postmortem Brain: An Underutilized Substrate for Studying Severe Mental Illness. NEUROPSYCHOPHARMACOLOGY. 1307-1307.
  Full Text via DOI: 10.1038/npp.2014.337
Early Access (Web of Science)
- 2022
  
  Schizophrenia: a disorder of broken brain bioenergetics. MOLECULAR PSYCHIATRY.
  Full Text via DOI: 10.1038/s41380-022-01494-x PMID: 35264726
- 2020
  
  Signature-based approaches for informed drug repurposing: targeting CNS disorders. NEUROPSYCHOPHARMACOLOGY.
  Full Text via DOI: 10.1038/s41386-020-0752-6 PMID: 32604402
Editorial Material (Web of Science)
- 2022
  
  Postmortem, in silico, and clinical studies focused on perturbations of glutamate neurobiology in schizophrenia. SCHIZOPHRENIA RESEARCH. 1-3.
  Full Text via DOI: 10.1016/j.schres.2022.07.020 PMID: 36088176
- 2022
  
  Editorial overview: Neuroscience: Advances in the field. CURRENT OPINION IN PHARMACOLOGY. 82-84.
  Full Text via DOI: 10.1016/j.coph.2021.11.004 PMID: 34942403
- 2015
  
  Evidence for Schizophrenia as a Disorder of Neuroplasticity. American Journal of Psychiatry. 312-313.
  Full Text via DOI: 10.1176/appi.ajp.2015.15010069
- 2015
  
  Regulation of Extrasynaptic Glutamate Levels as a Pathophysiological Mechanism in Disorders of Motivation and Addiction. NEUROPSYCHOPHARMACOLOGY. 254-255.
  Full Text via DOI: 10.1038/npp.2014.218
Letter (Web of Science)
- 2006
  
  Reply: Autoradiography of [3H]aspartate and Glutamate Transport in Schizophrenia. NEUROPSYCHOPHARMACOLOGY. 687-688.
  Full Text via DOI: 10.1038/sj.npp.1300978
Meeting Abstract (Web of Science)
- 2021
  
  Effect of antipsychotics on glucose sensing by the brain. PSYCHONEUROENDOCRINOLOGY. S15-S15.
  Full Text via DOI: 10.1016/j.psyneuen.2021.105507
- 2020
  
  Bilirubin: A Fat Busting Metabolic Hormone?. FASEB JOURNAL.
  Full Text via DOI: 10.1096/fasebj.2020.34.s1.00243
- 2019
  
  143. Kinome Analysis Identifies Glutamate-Related Kinase Network Dysregulation in Depression. BIOLOGICAL PSYCHIATRY. S59-S60.
  Full Text via DOI: 10.1016/j.biopsych.2019.03.157
- 2019
  
  21.4 CELL-TYPE SPECIFIC ALTERATIONS IN ADENOSINE-GENERATING PATHWAYS IN SCHIZOPHRENIA. SCHIZOPHRENIA BULLETIN. S124-S125.
  Full Text via DOI: 10.1093/schbul/sbz022.088
- 2019
  
  S181. Kaleidoscope: A New Bioinformatics Pipeline Application for in Silico Hypothesis Testing of Gene Expression Changes in Severe Mental Illness. BIOLOGICAL PSYCHIATRY. S367.
  Full Text via DOI: 10.1016/j.biopsych.2019.03.932
- 2019
  
  T84. Characterizing Signal Transduction Networks in Postmortem Depressed-Suicide Subjects. BIOLOGICAL PSYCHIATRY. S161.
  Full Text via DOI: 10.1016/j.biopsych.2019.03.407
- 2018
  
  12.1 CELL-SUBTYPE SPECIFIC BIOENERGETIC DEFECTS IN SCHIZOPHRENIA. SCHIZOPHRENIA BULLETIN. S19-S19.
  Full Text via DOI: 10.1093/schbul/sby014.044
- 2018
  
  12.2 METABOLIC CONSEQUENCES OF DEVELOPMENTAL NMDA RECEPTOR HYPOFUNCTION. SCHIZOPHRENIA BULLETIN. S19-S20.
  Full Text via DOI: 10.1093/schbul/sby014.045
- 2018
  
  32.2 ABNORMALITIES OF SYNAPTIC PROTEOMES IN SCHIZOPHRENIA. SCHIZOPHRENIA BULLETIN. S52-S53.
  Full Text via DOI: 10.1093/schbul/sby014.133
- 2018
  
  F201. KINASE NETWORK DYSREGULATION IN SCHIZOPHRENIA: IMPLICATIONS FOR NEW TREATMENT STRATEGIES. SCHIZOPHRENIA BULLETIN. S299-S299.
  Full Text via DOI: 10.1093/schbul/sby017.732
- 2011
  
  Genetic association and postmortem studies of D-serine modulator PAPST1 in schizophrenia. NEUROSCIENCE RESEARCH. e301.
  Full Text via DOI: 10.1016/j.neures.2011.07.1311
- 2003
  
  Expression of vesicular glutamate transporters one and two in medial temporal lobe structures in schizophrenia, bipolar disorder, and major depressive disorder. Schizophrenia Research. 65.
  Full Text via DOI: 10.1016/s0920-9964(03)80578-9
Review Article (Web of Science)
- 2022
  
  Adenosine, Schizophrenia and Cancer: Does the Purinergic System Offer a Pathway to Treatment?. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
  Full Text via DOI: 10.3390/ijms231911835 PMID: 36233136
- 2021
  
  Strategies to identify candidate repurposable drugs: COVID-19 treatment as a case example. TRANSLATIONAL PSYCHIATRY.
  Full Text via DOI: 10.1038/s41398-021-01724-w PMID: 34785660
- 2020
  
  Emerging Kinase Therapeutic Targets in Pancreatic Ductal Adenocarcinoma and Pancreatic Cancer Desmoplasia. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
  Full Text via DOI: 10.3390/ijms21228823 PMID: 33233470
- 2019
  
  Pioglitazone improves working memory performance when administered in chronic TBI. NEUROBIOLOGY OF DISEASE.
  Full Text via DOI: 10.1016/j.nbd.2019.104611 PMID: 31513844
- 2019
  
  Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies. MOLECULAR PSYCHIATRY. 995-1012.
  Full Text via DOI: 10.1038/s41380-018-0239-6
- 2018
  
  Role of glutamatergic system and mesocorticolimbic circuits in alcohol dependence. PROGRESS IN NEUROBIOLOGY. 32-49.
  Full Text via DOI: 10.1016/j.pneurobio.2018.10.001
- 2018
  
  Defects in Bioenergetic Coupling in Schizophrenia. BIOLOGICAL PSYCHIATRY. 739-750.
  Full Text via DOI: 10.1016/j.biopsych.2017.10.014
- 2017
  
  Glutamate Neurotransmission in Rodent Models of Traumatic Brain Injury. JOURNAL OF NEUROTRAUMA. 263-272.
  Full Text via DOI: 10.1089/neu.2015.4373
- 2017
  
  The role of glutamate transporters in the pathophysiology of neuropsychiatric disorders. npj Schizophrenia. 32.
  Full Text via DOI: 10.1038/s41537-017-0037-1
- 2014
  
  Postmortem Brain: An Underutilized Substrate for Studying Severe Mental Illness. NEUROPSYCHOPHARMACOLOGY. 65-87.
  Full Text via DOI: 10.1038/npp.2013.239
- 2009
  
  Vesicular glutamate transporter mRNA expression in the medial temporal lobe in major depressive disorder, bipolar disorder, and schizophrenia. Bipolar Disorders. 711-725.
  Full Text via DOI: 10.1111/j.1399-5618.2009.00752.x
- 2008
  
  High-affinity Na⁺/K⁺-dependent glutamate transporter EAAT4 is expressed throughout the rat fore- and midbrain. JOURNAL OF COMPARATIVE NEUROLOGY. 155-172.
  Full Text via DOI: 10.1002/cne.21823
- 2007
  
  Abnormal Glutamate Receptor Expression in the Medial Temporal Lobe in Schizophrenia and Mood Disorders. NEUROPSYCHOPHARMACOLOGY. 1888-1902.
  Full Text via DOI: 10.1038/sj.npp.1301312

full name

Robert E Smith

visualizations

Cumulative publications in Scholars@UToledo

Co-author Network