Von Grafenstein, Hermann

Hermann Von Grafenstein
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Positions

Associate Professor, Medicinal and Biological Chemistry , College of Pharmacy and Pharmaceutical Sciences

Contact Info

hermann.grafenstein@utoledo.edu

selected publications

Article (Faculty180)
- 2014
  
  Tight Association between Macrophages and Adipocytes in Obesity: Implications for Adipocyte Preparation. OBESITY. 22:1246-1255.
- 2011
  
  Expression and Purification of Isotopically Enriched MHC Binding Immunogenic Peptides for NMR Studies. International Journal of Peptide Research and Therapeutics. 17:137-45.
- 2006
  
  Dysregulated Toll-like receptor expression and signaling in bone marrow-derived macrophages at the onset of diabetes in the non-obese diabetic mouse. International immunology. 18:1101-13.
- 2000
  
  Regulation of TCR-induced IFN-gamma release from islet-reactive non-obese diabetic CD8(+) T cells by prostaglandin E(2) receptor signaling. International immunology. 12:851-60.
- 1999
  
  Role of inflammatory infiltrate in activation and effector function of cloned islet reactive nonobese diabetic CD8+ T cells: involvement of a nitric oxide-dependent pathway. Journal of immunology (Baltimore, Md. : 1950). 163:5770-80.
- 1998
  
  Modeling of the Non-Obese Diabetic Mouse Class II MHC Molecule I-Ag^ 7. Protein and Peptide Letters. 5:75-82.
- 1998
  
  Molecular identification of a role for tyrosine 167 in the function of the human intestinal proton- coupled dipeptide transporter (hPepT1). Biochemical and biophysical research communications. 250:103-7.
- 1997
  
  A model of water structure inside the HLA-A2 peptide binding groove. International Immunology. 9:1339-46.
- 1996
  
  Sequence dependent conformational motion of a peptide in the HLA-A2 binding groove. Protein and Peptide Letters. 3:51-8.
- 1994
  
  Self peptides isolated from MHC glycoproteins of non-obese diabetic mice. The Journal of Immunology. 152:2279-88.
- 1993
  
  TCR-CD4 and TCR-TCR interactions as distinctive mechanisms for the induction of increased intracellular calcium in T-cell signalling. The Journal of Immunology. 151:1337-45.
- 1993
  
  Triggered exocytosis and endocytosis have different requirements for calcium and nucleotides in permeabilized bovine chromaffin cells. The Journal of Membrane Biology. 134:1-3.
- 1992
  
  Membrane recapture and early triggered secretion from the newly formed endocytotic compartment in bovine chromaffin cells. The Journal of Physiology. 453:15-31.
- 1991
  
  Calcium export by sodium-calcium exchange in bovine chromaffin cells. Cell Calcium. 12:493-504.
- 1991
  
  The use of the polymerase chain reaction to map CD4+ T cell epitopes. European Journal of Immunology. 21:2851-5.
- 1989
  
  Activation of sodium channels is not essential for endothelin induced vasoconstriction. Pflügers Archiv-European Journal of Physiology. 413:313-5.
- 1986
  
  Kinetic analysis of the triggered exocytosis/endocytosis secretory cycle in cultured bovine adrenal medullary cells. The Journal of Cell Biology. 103:2343-52.
- 1981
  
  Interaction of chromaffin granules with plasma membranes mediated by Ca2+ and Mg-ATP using self-generating gradients of Percoll.. FEBS Letters. 123:238-240.
- 1980
  
  CA2+-MEDIATED AND ATP-MEDIATED INTERACTION OF CHROMAFFIN GRANULES WITH PLASMA-MEMBRANES OF BOVINE ADRENALE MEDULLA USING SELF-GENERATING PERCOLL-GRADIENTS. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE. 361:1288-1288.
Article (Web of Science)
- 2014
  
  Tight Association between Macrophages and Adipocytes in Obesity: Implications for Adipocyte Preparation. OBESITY. 22:1246-1255.
  Full Text via DOI: 10.1002/oby.20634
- 2011
  
  Expression and Purification of Isotopically Enriched MHC Binding Immunogenic Peptides for NMR Studies. INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS. 17:137-145.
  Full Text via DOI: 10.1007/s10989-011-9251-2
- 2006
  
  Dysregulated Toll-like receptor expression and signaling in bone marrow-derived macrophages at the onset of diabetes in the non-obese diabetic mouse. INTERNATIONAL IMMUNOLOGY. 18:1101-1113.
  Full Text via DOI: 10.1093/intimm/dxl045
- 2006
  
  Structural prediction of peptides binding to MHC class I molecules. Proteins: Structure, Function, and Bioinformatics. 63:43-52.
  Full Text via DOI: 10.1002/prot.20870
- 2003
  
  Antigen-independent cross-talk between macrophages and CD8+ T cells facilitates their cooperation during target destruction. International Immunology. 15:1063-1071.
  Full Text via DOI: 10.1093/intimm/dxg106
- 2000
  
  Cell-ELISA using β-galactosidase conjugated antibodies. Journal of Immunological Methods. 234:P153-P167.
  Full Text via DOI: 10.1016/s0022-1759(99)00216-1
- 2000
  
  Regulation of TCR-induced IFN-γ release from islet-reactive non-obese diabetic CD8+ T cells by prostaglandin E2 receptor signaling. International Immunology. 12:851-860.
  Full Text via DOI: 10.1093/intimm/12.6.851
- 2000
  
  Water dynamics at the binding interface of four different HLA-A2–peptide complexes. International Immunology. 12:949-957.
  Full Text via DOI: 10.1093/intimm/12.7.949
- 1998
  
  Molecular Identification of a Role for Tyrosine 167 in the Function of the Human Intestinal Proton- Coupled Dipeptide Transporter (hPepT1). BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 250:103-107.
  Full Text via DOI: 10.1006/bbrc.1998.9283
- 1998
  
  PGE2INHIBITS IL-2 AND IL-4-DEPENDENT PROLIFERATION OF CTLL-2 AND HT2 CELLS. CYTOKINE. 10:265-274.
  Full Text via DOI: 10.1006/cyto.1997.0288
- 1998
  
  Structure, Function, and Molecular Modeling Approaches to the Study of the Intestinal Dipeptide Transporter PepT1. JOURNAL OF PHARMACEUTICAL SCIENCES. 87:1286-1291.
  Full Text via DOI: 10.1021/js980090u
- 1997
  
  A model of water structure inside the HLA-A2 peptide binding groove. International Immunology. 9:1339-1346.
  Full Text via DOI: 10.1093/intimm/9.9.1339
- 1997
  
  Inhibition of diabetes by an insulin-reactive CD4 T-cell clone in the nonobese diabetic mouse. DIABETES. 46:1124-1132.
  Full Text via DOI: 10.2337/diabetes.46.7.1124
- 1992
  
  Membrane recapture and early triggered secretion from the newly formed endocytotic compartment in bovine chromaffin cells.. JOURNAL OF PHYSIOLOGY-LONDON. 453:15-31.
  Full Text via DOI: 10.1113/jphysiol.1992.sp019215
- 1992
  
  The effect of botulinum toxin type D on the triggered and constitutive exocytosis/endocytosis cycles in cultures of bovine adrenal medullary cells. FEBS LETTERS. 298:118-122.
  Full Text via DOI: 10.1016/0014-5793(92)80035-f
- 1991
  
  The use of the polymerase chain reaction to map CD4+ T cell epitopes. EUROPEAN JOURNAL OF IMMUNOLOGY. 21:2851-2855.
  Full Text via DOI: 10.1002/eji.1830211129
- 1989
  
  Ionic requirements of the endothelin response in aorta and portal vein.. CIRCULATION RESEARCH. 65:265-271.
  Full Text via DOI: 10.1161/01.res.65.2.265
- 1989
  
  Tissue selectivity of endothelin. EUROPEAN JOURNAL OF PHARMACOLOGY. 165:223-230.
  Full Text via DOI: 10.1016/0014-2999(89)90716-4
- 1986
  
  Kinetic analysis of the triggered exocytosis/endocytosis secretory cycle in cultured bovine adrenal medullary cells.. JOURNAL OF CELL BIOLOGY. 103:2343-2352.
  Full Text via DOI: 10.1083/jcb.103.6.2343
Conference Poster (Faculty180)
Lecture or Panel Discussion (Faculty180)
- 2021
  
  COVID-19 Vaccination: Dvelopment, Distribution, and Psychosicial Impacts. 2021 Spring Asia Forum.
Note (Web of Science)
- 1989
  
  Activation of sodium channels is not essential for endothelin induced vasoconstriction. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 313-315.
  Full Text via DOI: 10.1007/bf00583546
Review Article (Web of Science)
- 1989
  
  Calcium-dependent and calcium-independent exocytosis. Trends in Neurosciences. 451-458.
  Full Text via DOI: 10.1016/0166-2236(89)90095-7

full name

Hermann Von Grafenstein

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