Bain, William; Tabary, Mohammadreza; Moore, Sara R; An, Xiaojing; Kitsios, Georgios D; McVerry, Bryan J; Ray, Prabir; Ray, Anuradha; Mallampalli, Rama K; Ferreira, Viviana P; Lee, Janet S; Nouraie, S Mehd M
description
Effective regulation of complement activation may be crucial to preserving complement function during acute respiratory distress syndrome (ARDS). Factor H is the primary negative regulator of the alternative pathway of complement. We hypothesised that preserved factor H levels are associated with decreased complement activation and reduced mortality during ARDS.
