In Vivo Evolution of a Klebsiella pneumoniae Capsule Defect With wcaJ Mutation Promotes Complement-Mediated Opsonophagocytosis During Recurrent Infection Article (Faculty180)

cited authors

  • Bain, William; Ahn, Brian; Peñaloza, Hernán F; McElheny, Christi L; Tolman, Nathanial; van der Geest, Rick; Gonzalez-Ferrer, Shekina; Chen, Nathalie; An, Xiaojing; Hosuru, Ria; Tabary, Mohammadreza; Papke, Erin; Kohli, Naina; Farooq, Nauman; Bachman, William; Olonisakin, Tolani F; Xiong, Zeyu; Griffith, Marissa P; Sullivan, Mara; Franks, Jonathan; Mustapha, Mustapha M; Iovleva, Alina; Suber, Tomeka; Shanks, Robert Q; Ferreira, Viviana P; Stolz, Donna B; Van Tyne, Daria; Doi, Yohei; Lee, Janet S

description

  • Klebsiella pneumoniae carbapenemase-producing K pneumoniae (KPC-Kp) bloodstream infections are associated with high mortality. We studied clinical bloodstream KPC-Kp isolates to investigate mechanisms of resistance to complement, a key host defense against bloodstream infection.

authors

publication date

  • 2024

published in

start page

  • 209

end page

  • 220

volume

  • 230