Synthesis and Pharmacological Evaluation of Novel Triazole-Pyrimidine Hybrids as Potential Neuroprotective and Anti-neuroinflammatory Agents Article (Faculty180)

cited authors

  • Manzoor, Shoaib; Almarghalani, D A; James, Antonisamy W; Raza, Md K; Kausar, Tasneem; Nayeem, Shahid M; Hoda, Nasimul; Shah, Z A


  • Neuroprotection is a precise target for the treatment of neurodegenerative diseases, ischemic stroke, and traumatic brain injury. Pyrimidine and its derivatives have been proven to use antiviral, anticancer, antioxidant, and antimicrobial activity prompting us to study the neuroprotection and anti-inflammatory activity of the triazole-pyrimidine hybrid on human microglia and neuronal cell model.


publication date

  • 2023

published in

start page

  • 167

end page

  • 185


  • 40