Rat Models of Exercise for the Study of Complex Disease Article (Faculty180)

cited authors

  • Koch, Lauren G; Britton, Steven L


  • Variation in exercise capacity is a translationally powerful indicator for overall health and disease. Here we review the basic methods used for development of theoretically based and hypothesis-driven rat models that divide for both exercise capacity and numerous complex disease risks This rat model system was made by selectively breeding genetically heterogeneous rat populations for low and high performance on a speed ramped treadmill running test.

publication date

  • 2019

start page

  • 309

end page

  • 317


  • 2018