Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells Article (Faculty180)

cited authors

  • Valdivia, Alejandra; Cárdenas, Areli; Brenet, Marianne; Maldonado, Horacio; Kong, Milene; Díaz, Jorge; Burridge, Keith; Schneider, Pascal; San Martín, Alejandra; García-Mata, Rafael; Quest, Andrew F G; Leyton, Lisette


  • Syndecans regulate cell migration thus having key roles in scarring and wound healing processes. Our previous results have shown that Thy-1/CD90 can engage both αvβ3 integrin and Syndecan-4 expressed on the surface of astrocytes to induce cell migration. Despite a well-described role of Syndecan-4 during cell movement, information is scarce regarding specific Syndecan-4 partners involved in Thy-1/CD90-stimulated cell migration.

publication date

  • 2020

start page

  • 129


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