Obrenovich, Mark E; Donskey, Curtis J; Schiefer, Isaac T; Bongiovanni, Rodolfo; Li, Ling; Jaskiw, G E
description
Co-metabolism between a human host and the gastrointestinal microbiota generates many small phenolic molecules such as 3-hydroxy-3-(3-hydroxyphenyl)propanoic acid (3,3-HPHPA), which are reported to be elevated in schizophrenia and autism. Characterization of these chemicals, however, has been limited by analytic challenges.