Impact of Smoking on Platelet Reactivity and Clinical Outcomes After Percutaneous Coronary Intervention: Findings From the ADAPT-DES Study Article (Faculty180)

cited authors

  • Gupta, Rajesh; Kirtane, A J; Liu, Yangbo; Crowley, Aaron; Witzenbichler, Bernhard; Rinaldi, Michael J; Metzger, D C; Weisz, Giora; Stuckey, Thomas D; Brodie, B R; Mehran, Roxana; Ben-Yehuda, Ori; Stone, Gregg W


  • Smoking is a potent risk factor for coronary artery disease; however, prior studies describe increased platelet inhibition with clopidogrel among smokers, and some studies report improved outcomes among smokers, a finding described as the smoker's paradox. This study assessed the relationship between platelet reactivity and clinical outcomes after percutaneous coronary interventions among current smokers and nonsmokers.


publication date

  • 2019

start page

  • e007982


  • 12