Interleukin-6 induces neuroendocrine differentiation (NED) through suppression of RE-1 silencing transcription factor (REST) Article (Faculty180)

cited authors

  • Zhu, Yezi; Liu, Chengfei; Cui, Yuanyuan; Nadiminty, Nagalakshmi; Lou, Wei; Gao, Allen C


  • Paracrine interleukin-6 (IL-6) can mediate neuroendocrine (NE) features, including the acquisition of a neurite-like phenotype and growth arrest in prostate cancer cells. However, little is known about the mechanisms underlying neuroendocrine differentiation induced by IL-6.

publication date

  • 2014

published in

start page

  • 1086

end page

  • 94


  • 74