The N-terminal kinase suppressor of Ras complex has a weak nucleoside diphosphate kinase activity Article (Faculty180)

cited authors

  • Yang, Xueqin; You, Jiacong; Luo, Wei; Yue, Jiao; Ma, Li; Xiao, Wen; Zhu, Daxing; Wu, Zhihao; Wang, Dong; Nadiminty, Nagalakshmi; Gao, Allen C; Zhou, Qinghua


  • An increasing number of studies have proven that the kinase suppressor of Ras (KSR1) functions as a scaffolding protein that coordinates the assembly of a multiprotein complex containing mitogen-activated protein kinase and its upstream regulators. However, a few studies have reported that KSR1 can activate c-Raf-1. Therefore, whether KSR1 possesses a kinase activity has been an unresolved issue until now.

publication date

  • 2010

published in

start page

  • 109

end page

  • 115


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