Requirement for NF-(kappa)B in interleukin-4-induced androgen receptor activation in prostate cancer cells Article (Faculty180)

cited authors

  • Lee, Soo Ok; Lou, Wei; Nadiminty, Nagalakshmi; Lin, Xin; Gao, Allen C


  • Accumulating evidence suggest a critical role of activation of androgen receptor (AR) by nonandrogen in the development of androgen independent prostate cancer. Previous study identified that interleukin-4 (IL-4) enhances AR activation in the absence of androgen or in the very low levels of androgen in prostate cancer cells. In this study, the mechanism of IL-4-induced AR activation was investigated.

publication date

  • 2005

published in

start page

  • 160

end page

  • 7


  • 64