Discovery of novel MDM2 inhibitors from a Penicillium metabolome library: An integrated phylogenetic, machine learning, and molecular simulation approach Article (Web of Science)

cited authors

  • Biniyam, Prince Danan; Kayeri, Naomi; Buabeng, Jesse Ayim; Aboagye, Dickson; Hammah, Alberta; Haider, Syed Arslan; Nkrumah, Lawrence Kwame; Adu-Adjei, Kwabena; Ohene-Adu, Victoria; Osei, Michael; Penajah, Clifford Tignangnen; Narh, Peter Bedman; Amengor, Cedric Dzidzor Kodjo

publication date

  • May 1, 2026

webpage

published in

category

keywords

  • Ensemble docking
  • MDM2 inhibitors
  • Machine learning QSAR
  • Molecular dynamics simulations
  • Natural product drug discovery
  • Network pharmacology
  • Penicillium metabolites
  • p53 tumor suppressor

volume

  • 146