Peseckis, Steven M

Steven M Peseckis
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Positions

Associate Professor, Medicinal and Biological Chemistry , College of Pharmacy and Pharmaceutical Sciences

Contact Info

steven.peseckis@utoledo.edu

overview

Highlights
- Dartmouth BA, MIT PhD, Princeton/Sloan Kettering Cancer Center Post-Doctoral
- 29 Years in Higher Education, 7 Years Industrial Experience
- Content Expertise includes Infectious Disease, Microbiology, Oncology, Cell Biology, Molecular Biology, Drug Targeting and Delivery, Pharmaceutical Techniques, Medicinal Plants, Alternative Medicine, Cannabis Science
- Administrative Expertise includes Curriculum, Assessment, Accreditation, Alumni Affairs, Event Organization, Fundraising, Research Integrity, Human Safety
- Chosen 10 times by Students as Outstanding Professor in Pharmacy College
- Trained 5 PhDs, Served on over 75 Graduate Thesis Committees
- Interdisciplinary/Interprofessional Teamwork, Community Engagement
- Vice Chair UT IBC and IRB, Vice Chair Promedica IRB, Chair UT hSCRO

selected publications

Article (Web of Science)
- 2011
  
  Fatty acylation enhances cellular localization of dansylated phenylalanines. MOLECULAR AND CELLULAR BIOCHEMISTRY. 346:81-87.
  Full Text via DOI: 10.1007/s11010-010-0593-4
- 1999
  
  Differential modulation of agonist potency and receptor coupling by mutations of Ser388Tyr and Thr389Pro at the junction of transmembrane domain VI and the third extracellular loop of human M(1) muscarinic acetylcholine receptors.. MOLECULAR PHARMACOLOGY. 56:775-83.
  PMID: 10496961
- 1999
  
  First fatty acylated dipeptides to affect muscarinic receptor ligand binding. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 9:3363-3368.
  Full Text via DOI: 10.1016/s0960-894x(99)00604-6
- 1999
  
  Roles of threonine 192 and asparagine 382 in agonist and antagonist interactions with M₁muscarinic receptors. British Journal of Pharmacology. 126:735-745.
  Full Text via DOI: 10.1038/sj.bjp.0702301
- 1994
  
  Regulation of enzymatic activity by active site fatty acylation. A new role for long chain fatty acid acylation of proteins.. JOURNAL OF BIOLOGICAL CHEMISTRY. 269:6498-505.
  PMID: 8120000
- 1993
  
  Iodinated fatty acids as probes for myristate processing and function. Incorporation into pp60v-src.. JOURNAL OF BIOLOGICAL CHEMISTRY. 268:5107-14.
  PMID: 8444887
- 1993
  
  Novel use of an iodo-myristyl-CoA analog identifies a semialdehyde dehydrogenase in bovine liver.. JOURNAL OF BIOLOGICAL CHEMISTRY. 268:13738-47.
  PMID: 8514806
- 1988
  
  Chemistry and positive inotropic effect of pelrinone and related derivatives. A novel class of 2-methylpyrimidones as inotropic agents. JOURNAL OF MEDICINAL CHEMISTRY. 31:814-823.
  Full Text via DOI: 10.1021/jm00399a023
- 1983
  
  Regioselectivity of the reactions of trialkylaluminum reagents with 2,3-epoxyalcohols: Application to the synthesis of α-chiral aldehydes. TETRAHEDRON LETTERS. 24:1377-1380.
  Full Text via DOI: 10.1016/s0040-4039(00)81660-3
- 1982
  
  Studies on the total synthesis of antibiotic X-14547A: the pentaene approach. TETRAHEDRON LETTERS. 23:4879-4882.
  Full Text via DOI: 10.1016/s0040-4039(00)85737-8
- 1981
  
  Intramolecular Diels-Alder reactions: the angularly methylated trans-perhydroindan ring system. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 103:6696-6704.
  Full Text via DOI: 10.1021/ja00412a027
Letter (Web of Science)
- 1984
  
  Synthesis of antibiotic X-14547A. JOURNAL OF ORGANIC CHEMISTRY. 3429-3432.
  Full Text via DOI: 10.1021/jo00192a052
Meeting Abstract (Web of Science)
- 1999
  
  Mutant M1 muscarinic receptors with enhanced agonist activity. LIFE SCIENCES. 563.
  Full Text via DOI: 10.1016/s0024-3205(99)90481-2
- 1999
  
  Mutant M1 muscarinic receptors with increased agonist affinity and G protein coupling. LIFE SCIENCES. 563.
  Full Text via DOI: 10.1016/s0024-3205(99)90482-4

full name

Steven M Peseckis

visualizations

Cumulative publications in Scholars@UToledo

Co-author Network

research areas

Cell Biology