Steven M Peseckis
- Associate Professor, Medicinal and Biological Chemistry , College of Pharmacy and Pharmaceutical Sciences
Contact Info
Overview
overview
-
Highlights
- Dartmouth BA, MIT PhD, Princeton/Sloan Kettering Cancer Center Post-Doctoral
- 29 Years in Higher Education, 7 Years Industrial Experience
- Content Expertise includes Infectious Disease, Microbiology, Oncology, Cell Biology, Molecular Biology, Drug Targeting and Delivery, Pharmaceutical Techniques, Medicinal Plants, Alternative Medicine, Cannabis Science
- Administrative Expertise includes Curriculum, Assessment, Accreditation, Alumni Affairs, Event Organization, Fundraising, Research Integrity, Human Safety
- Chosen 10 times by Students as Outstanding Professor in Pharmacy College
- Trained 5 PhDs, Served on over 75 Graduate Thesis Committees
- Interdisciplinary/Interprofessional Teamwork, Community Engagement
- Vice Chair UT IBC and IRB, Vice Chair Promedica IRB, Chair UT hSCRO
Publications
selected publications
-
Article (Faculty180)
-
2011Fatty acylation enhances cellular localization of dansylated phenylalanines. Mol Cell Biochem. 346:81-87.
-
1999First Fatty Acylated Dipeptides to Affect Muscarinic Receptor Ligand Binding. Bioorganic & Medicinal Chemistry Letters. 9:3363-3368.
-
1998
-
1997Molecular studies of agonist interactions with wild-type, T234A, and N507A m3 receptors.. Life Sciences . 60:1178.
-
1994Dual Myristylation and Palmitylation of Src Family Member p59fyn Affects Subcellular Localization. J. Biol. Chem. 269:16701-16705.
-
1994Fatty Acyl Transfer by Human N-Myristyl Transferase Is Dependent Upon Conserved Cysteine and Histidine Residues. J. Biol. Chem. 269:30888-30892.
-
1994Regulation of enzymatic activity by active site acylation: A new role for long chain fatty acid acylation of proteins. J. Biol. Chem. . 268:13738-13747.
-
1993Iodinated Fatty Acids as Probes for Myristate Processing and Function Incorporation into pp60v-src. The Journal of Biological Chemistry. 268:5107-5114.
-
1984Synthesis of X-14547A. J. Organic Chemistry. 49:3429-3432.
-
1983Regioselectivity of the Reactions of Trialkylaluminum Reagents with 2,3-epoxyalcohols: Application to the Synthesis of alpha-Chiral Aldehydes. Tetrahedron Letters. 24:1377-1380.
-
1982Studies on the Total Synthesis of Antibiotic X-14547A The Pentaene Approach. Tetrahedron Letters. 23:4879-4882.
-
1981Intramolecular Reactions: The Angularly Methylated trans-Perhydroindan Ring System. J. Am. Chem. Soc.. 103:6696-6704.
-
-
Article (Web of Science)
-
2011Fatty acylation enhances cellular localization of dansylated phenylalanines. MOLECULAR AND CELLULAR BIOCHEMISTRY. 346:81-87.Full Text via DOI: 10.1007/s11010-010-0593-4
-
1999First fatty acylated dipeptides to affect muscarinic receptor ligand binding. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 9:3363-3368.Full Text via DOI: 10.1016/s0960-894x(99)00604-6
-
1999Roles of threonine 192 and asparagine 382 in agonist and antagonist interactions with M1muscarinic receptors. British Journal of Pharmacology. 126:735-745.Full Text via DOI: 10.1038/sj.bjp.0702301
-
1994Regulation of enzymatic activity by active site fatty acylation. A new role for long chain fatty acid acylation of proteins.. JOURNAL OF BIOLOGICAL CHEMISTRY. 269:6498-505.PMID: 8120000
-
1993Iodinated fatty acids as probes for myristate processing and function. Incorporation into pp60v-src.. JOURNAL OF BIOLOGICAL CHEMISTRY. 268:5107-14.PMID: 8444887
-
1993Novel use of an iodo-myristyl-CoA analog identifies a semialdehyde dehydrogenase in bovine liver.. JOURNAL OF BIOLOGICAL CHEMISTRY. 268:13738-47.PMID: 8514806
-
1988Chemistry and positive inotropic effect of pelrinone and related derivatives. A novel class of 2-methylpyrimidones as inotropic agents. JOURNAL OF MEDICINAL CHEMISTRY. 31:814-823.Full Text via DOI: 10.1021/jm00399a023
-
1983Regioselectivity of the reactions of trialkylaluminum reagents with 2,3-epoxyalcohols: Application to the synthesis of α-chiral aldehydes. TETRAHEDRON LETTERS. 24:1377-1380.Full Text via DOI: 10.1016/s0040-4039(00)81660-3
-
1982Studies on the total synthesis of antibiotic X-14547A: the pentaene approach. TETRAHEDRON LETTERS. 23:4879-4882.Full Text via DOI: 10.1016/s0040-4039(00)85737-8
-
1981Intramolecular Diels-Alder reactions: the angularly methylated trans-perhydroindan ring system. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 103:6696-6704.Full Text via DOI: 10.1021/ja00412a027
-
-
Chapter (Faculty180)
-
1995Synthesis and use of iodo-fatty acid analogs. Methods Enzymology: Lipid Modifications of Proteins . 454-466.
-
-
Dissertation (Faculty180)
-
Letter (Web of Science)
-
1984Synthesis of antibiotic X-14547A. JOURNAL OF ORGANIC CHEMISTRY. 3429-3432.Full Text via DOI: 10.1021/jo00192a052
-
-
Meeting Abstract (Web of Science)
-
1999Mutant M1 muscarinic receptors with enhanced agonist activity. LIFE SCIENCES. 563.Full Text via DOI: 10.1016/s0024-3205(99)90481-2
-
1999Mutant M1 muscarinic receptors with increased agonist affinity and G protein coupling. LIFE SCIENCES. 563.Full Text via DOI: 10.1016/s0024-3205(99)90482-4
-
-
Patent (Faculty180)
Contact
full name
- Steven M Peseckis
visualizations
Cumulative publications in Scholars@UToledo