Silvia M Goicoechea
- Assistant Research Professor, Biological Sciences , College of Natural Sciences and Mathematics
Publications
selected publications
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Article (Web of Science)
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2021FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma. CELL REPORTS. 37.Full Text via DOI: 10.1016/j.celrep.2021.109905 PMID: 34731623
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2019SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility. JOURNAL OF CELL BIOLOGY. 218:2699-2725.Full Text via DOI: 10.1083/jcb.201811114 PMID: 31248911
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2019The small GTPase RhoG regulates microtubule-mediated focal adhesion disassembly. SCIENTIFIC REPORTS. 9.Full Text via DOI: 10.1038/s41598-019-41558-7 PMID: 30914742
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2017Regulation of circular dorsal ruffles, macropinocytosis, and cell migration by RhoG and its exchange factor, Trio. MOLECULAR BIOLOGY OF THE CELL. 28:1768-1781.Full Text via DOI: 10.1091/mbc.E16-06-0412
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2017A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells. JOURNAL OF CELL SCIENCE. 130:1064-1077.Full Text via DOI: 10.1242/jcs.195552
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2017mDia2 and CXCL12/CXCR4 chemokine signaling intersect to drive tumor cell amoeboid morphological transitions. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 484:255-261.Full Text via DOI: 10.1016/j.bbrc.2017.01.087
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2017Regulation of circular dorsal ruffles, macropinocytosis, and cell migration by RhoG and its exchange factor, Trio. MOLECULAR BIOLOGY OF THE CELL. 28:1768-1781.Full Text via DOI: 10.1091/mbc.e16-06-0412
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2016The actin crosslinking protein palladin modulates force generation and mechanosensitivity of tumor associated fibroblasts. SCIENTIFIC REPORTS. 6.Full Text via DOI: 10.1038/srep28805
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2015Palladin expression is a conserved characteristic of the desmoplastic tumor microenvironment and contributes to altered gene expression. CYTOSKELETON. 72:402-411.Full Text via DOI: 10.1002/cm.21239
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2014Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation in cancer-associated fibroblasts. ONCOGENE. 33:1265-1273.Full Text via DOI: 10.1038/onc.2013.68
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2013Structure and Function of Palladin's Actin Binding Domain. JOURNAL OF MOLECULAR BIOLOGY. 425:3325-3337.Full Text via DOI: 10.1016/j.jmb.2013.06.016
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2010Isoform-Specific Upregulation of Palladin in Human and Murine Pancreas Tumors. PLOS ONE. 5:e10347.Full Text via DOI: 10.1371/journal.pone.0010347
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2010The Actin Associated Protein Palladin Is Important for the Early Smooth Muscle Cell Differentiation. PLOS ONE. 5:e12823.Full Text via DOI: 10.1371/journal.pone.0012823
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2009Characterization of cortactin as an in vivo protein kinase D substrate: Interdependence of sites and potentiation by Src. CELLULAR SIGNALLING. 21:253-263.Full Text via DOI: 10.1016/j.cellsig.2008.10.015
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2009Palladin contributes to invasive motility in human breast cancer cells. ONCOGENE. 28:587-598.Full Text via DOI: 10.1038/onc.2008.408
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2008The role of palladin in actin organization and cell motility. European Journal of Cell Biology. 87:517-525.Full Text via DOI: 10.1016/j.ejcb.2008.01.010
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2006Palladin binds to Eps8 and enhances the formation of dorsal ruffles and podosomes in vascular smooth muscle cells. JOURNAL OF CELL SCIENCE. 119:3316-3324.Full Text via DOI: 10.1242/jcs.03076
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2003Low density lipoprotein receptor–related protein is a calreticulin coreceptor that signals focal adhesion disassembly. JOURNAL OF CELL BIOLOGY. 161:1179-1189.Full Text via DOI: 10.1083/jcb.200302069
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2002Nck-2 interacts with focal adhesion kinase and modulates cell motility. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. 34:791-805.Full Text via DOI: 10.1016/s1357-2725(02)00002-x
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2002The Anti-adhesive Activity of Thrombospondin Is Mediated by the N-terminal Domain of Cell Surface Calreticulin. JOURNAL OF BIOLOGICAL CHEMISTRY. 277:37219-37228.Full Text via DOI: 10.1074/jbc.m202200200
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2000Thrombospondin Mediates Focal Adhesion Disassembly through Interactions with Cell Surface Calreticulin. JOURNAL OF BIOLOGICAL CHEMISTRY. 275:36358-36368.Full Text via DOI: 10.1074/jbc.m005951200
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1998Integrin-linked Protein Kinase Regulates Fibronectin Matrix Assembly, E-cadherin Expression, and Tumorigenicity. JOURNAL OF BIOLOGICAL CHEMISTRY. 273:528-536.Full Text via DOI: 10.1074/jbc.273.1.528
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1996Estimation of ubiquitin and ubiquitin mRNA content in dark senescing wheat leaves. BIOLOGIA PLANTARUM. 38.Full Text via DOI: 10.1007/bf02896657
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1994Effect of Dietary Level of Protein on the Activity of Mouse Liver Calpain. Hormone and Metabolic Research. 26:175-180.Full Text via DOI: 10.1055/s-2007-1000806
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Meeting Abstract (Web of Science)
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2016A RhoG-mediated signaling pathway that modulates invadopodia formation in breast cancer cells.. MOLECULAR BIOLOGY OF THE CELL.
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2016Regulation of circular dorsal ruffles, macropinocytosis and cell migration by RhoG and its exchange factor Trio.. MOLECULAR BIOLOGY OF THE CELL.
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2016The small GTPase RhoG modulates focal adhesion turnover.. MOLECULAR BIOLOGY OF THE CELL.
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2014RhoG Negatively Regulates Invadopodia Formation.. MOLECULAR BIOLOGY OF THE CELL.
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2014The Actin Crosslinking Protein Palladin Modulates Force Generation and Mechanical Sensing of Tumor Associated Fibroblasts. BIOPHYSICAL JOURNAL. 786a.Full Text via DOI: 10.1016/j.bpj.2013.11.4307
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2013The actin-binding protein palladin localizes to the nucleus of pancreatic tumor-associated fibroblasts and regulates gene expression. CANCER RESEARCH.Full Text via DOI: 10.1158/1538-7445.FBCR13-B46
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2013
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2012A novel PDGF-mediated RhoG pathway in vascular smooth muscle cells.. MOLECULAR BIOLOGY OF THE CELL.
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2012Palladin Cycles Between the Stress Fibers and the Nucleus to Regulate Transcription During Myofibroblast Differentiation. MOLECULAR BIOLOGY OF THE CELL.
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2012Palladin expression modulates RhoG activation, migration and invasion of breast cancer cells.. MOLECULAR BIOLOGY OF THE CELL.
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Review Article (Web of Science)
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2014I'm coming to GEF you Regulation of RhoGEFs during cell migration. CELL ADHESION & MIGRATION. 535-549.Full Text via DOI: 10.4161/cam.28721
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2009Cytoplasmic Ig-domain proteins: Cytoskeletal regulators with a role in human disease. Cell Motility and the Cytoskeleton. 618-634.Full Text via DOI: 10.1002/cm.20385
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Contact
full name
- Silvia M Goicoechea
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Cumulative publications in Scholars@UToledo