Shobha Ratnam
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Professor
Associate Program Director, Nephrology Training Program, Medicine , College of Medicine and Life Sciences
Contact Info
Overview
overview
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I am an Associate Professor of Medicine in the Division of Nephrology. I am currently board certified in Nephrology with an Ohio State license and am engaged in continuing medical education to maintain my license and certification.
I joined the faculty of the Medical College of Ohio (now the University of Toledo College of Medicine) in July 2004 after graduating with an MD degree, receiving residency training in Internal Medicine, Board certification in Internal Medicine and completing a Nephrology fellowship, all in this school. My education and training prior to joining medical school was quite extensive and a path of self-discovery that shaped my long-term career. This included a bachelor’s degree in basic science, a 3-year master’s degree in clinical biochemistry, a PhD degree in biomedical sciences and an NIH post-doctoral research fellowship at the University of Michigan in Ann Arbor. During my PhD training and during my medical education I had and raised two wonderful and bright children. I believe that all of the effort that I put into attaining my long-term goal of becoming an academic clinician was driven by my strong determination and an extreme passion to learn and teach medicine and to serve humanity; these are my major personal strengths. I owe my success to the generous help of excellent mentors during the many years of my research and medical training. My goal is to continue to strive towards excellence in my career.
Publications
selected publications
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Article (Faculty180)
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2020Calciphylaxis: a devastating complication of derangements of calcium-phosphorus metabolism--a case report and review of the literature. Nephrology nursing journal : journal of the American Nephrology Nurses' Association. 40:431-5; quiz 436.
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2018Unusual Finding of a Leiomyoma in Transplanted Kidney-Review of Literature and Implications for Management. Journal of Nephrology and Urology. 1:1-3.
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2016Acyclovir-Induced Neurotoxicity: A Case Report and Review of Literature . American Journal of Therapeutics. 23:e941-3.
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2014Survivin-induced abnormal ploidy contributes to cystic kidney and aneurysm formation. Circulation. 129:660-72.
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2013Conservative management of post-transplant central nervous system lymphoma. International urology and nephrology. 45:1219-22.
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2012Successful preemptive renal retransplantation in a patient with previous acute graft loss secondary to HIT type II: a case report and review of literature. International urology and nephrology. 44:991-4.
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2011
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2011Postārenal transplant plasma cell dyscrasia presenting as retroperitoneal plasmacytoma: A case report and literature review. Dialysis and Transplantation. 40:130-132.
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2010Aggressive posttransplant lymphoproliferative disease in a renal transplant patient treated with alemtuzumab. American journal of therapeutics. 17:e230-3.
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2010Hypertension in Autosomal Dominant Polycystic Kidney Disease: A Clinical and Basic Science Perspective. International journal of nephrology & urology. 2:294-308.
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2010Microscopic polyangiitis triggered by recurrent methicillin-resistant Staphylococcus aureus bacteremia. International urology and nephrology. 42:821-4.
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2009Ciliary polycystin-2 is a mechanosensitive calcium channel involved in nitric oxide signaling cascades. Circulation research. 104:860-9.
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2005Insulin acutely decreases hepatic fatty acid synthase activity. Cell metabolism. 2:43-53.
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2005Rhabdomyolysis complicating urosepsis in a renal transplant patient. Infections in Medicine. 22:123-129.
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2003Paricalcitol, calcitriol, and survival of patients undergoing hemodialysis. The New England journal of medicine. 349:1971.
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2003Use of methylene blue for diagnosis of leak in CAPD patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 18:2682; author reply 2682-3.
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1995Early increase in choline kinase activity upon induction of the H-ras oncogene in mouse fibroblast cell lines. Archives of Biochemistry and Biophysics. 323:313-317.
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1995Cloning, nucleotide sequence and expression of the bifunctional dihydrofolate reductase-thymidylate synthase from Glycine max. Biochimica et Biophysica Acta. 1261:325-330.
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1989Anti-idiotypic antibodies elicited by pterin recognize active site epitopes in dihydrofolate reductases and dihydropteridine reductase. Archives of Biochemistry and Biophysics. 275:344-349.
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1987Purification and Characterization of Dihydrofolate Reductase from Soybean Seedlings. Archives of Biochemistry and Biophysics. 225:27-30.
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1982Glycosylated haemoglobin in chronic renal failure. Indian Journal of Medical Research.
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Article (Web of Science)
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2014Survivin-Induced Abnormal Ploidy Contributes to Cystic Kidney and Aneurysm Formation. CIRCULATION. 129:660-672.Full Text via DOI: 10.1161/CIRCULATIONAHA.113.005746
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2014Survivin-Induced Abnormal Ploidy Contributes to Cystic Kidney and Aneurysm Formation. CIRCULATION. 129:660-672.Full Text via DOI: 10.1161/circulationaha.113.005746
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2013Conservative management of post-transplant central nervous system lymphoma. INTERNATIONAL UROLOGY AND NEPHROLOGY. 45:1219-1222.Full Text via DOI: 10.1007/s11255-012-0146-8
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2012Successful preemptive renal retransplantation in a patient with previous acute graft loss secondary to HIT type II: a case report and review of literature. INTERNATIONAL UROLOGY AND NEPHROLOGY. 44:991-994.Full Text via DOI: 10.1007/s11255-011-9935-8
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2011Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation. HUMAN MOLECULAR GENETICS. 20:354-367.Full Text via DOI: 10.1093/hmg/ddq470
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2010Aggressive Posttransplant Lymphoproliferative Disease in a Renal Transplant Patient Treated With Alemtuzumab. AMERICAN JOURNAL OF THERAPEUTICS. 17:E230-E233.Full Text via DOI: 10.1097/MJT.0b013e3181c08042
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2010Microscopic polyangiitis triggered by recurrent methicillin-resistant Staphylococcus aureus bacteremia. INTERNATIONAL UROLOGY AND NEPHROLOGY. 42:821-824.Full Text via DOI: 10.1007/s11255-009-9652-8
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2010Aggressive Posttransplant Lymphoproliferative Disease in a Renal Transplant Patient Treated With Alemtuzumab. AMERICAN JOURNAL OF THERAPEUTICS. 17:e230-e233.Full Text via DOI: 10.1097/mjt.0b013e3181c08042
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2009Ciliary Polycystin-2 Is a Mechanosensitive Calcium Channel Involved in Nitric Oxide Signaling Cascades. CIRCULATION RESEARCH. 104:860-869.Full Text via DOI: 10.1161/CIRCRESAHA.108.192765
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2009Ciliary Polycystin-2 Is a Mechanosensitive Calcium Channel Involved in Nitric Oxide Signaling Cascades. CIRCULATION RESEARCH. 104:860-869.Full Text via DOI: 10.1161/circresaha.108.192765
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Chapter (Faculty180)
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2010Pathogenesis and management of metabolic acidosis and alkalosis. Renal and Electrolyte Disorders, 7th Edition.
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1986Dihydrofolate reductase from glycine max. Chemistry and Biology of Pteridines Ed. Cooper B.
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Meeting Abstract (Web of Science)
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2009Differentiation of mechanical forces in perfused artery. FASEB JOURNAL.
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Review Article (Web of Science)
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2013Calciphylaxis: A Devastating Complication of Derangements Of Calcium-Phosphorus Metabolism - A Case Report and Review of the Literature. NEPHROLOGY NURSING JOURNAL. 431-435.
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2011Post-Renal Transplant Plasma Cell Dyscrasia Presenting as Retroperitoneal Plasmacytoma: A Case Report and Literature Review. DIALYSIS & TRANSPLANTATION. 130-132.Full Text via DOI: 10.1002/dat.20539
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Contact
full name
- Shobha Ratnam