Sailaja Paruchuri

Positions
Contact Info
https://www.utoledo.edu/med/depts/physpharm/faculty/Paruchuri.html

overview

  • Dr. Sailaja Paruchuri is a Professor in the Department of Physiology and Pharmacology at the University of Toledo. She obtained Ph.D. from the College of Medicine, Department of Experimental Pathogy, Lund University, Sweden. She then moved to Harvard Medical School and did post-doctoral training at Vascular Biology Program, Boston Children's Hospital and Brigham and Women's Hospital.  Later, she held a research position at the Lerner Research Institute, Cleveland Clinic Foundation before joining the University of Akron as an Assistant Professor and later promoted tenured Associate professor.

                Dr. Paruchuri’s lab focuses on elucidating eicosanoid (leukotrienes and prostaglandin) signaling in causing endothelial dysfunction, heart and lung remodeling during cardiac fibrosis and chronic asthma. Eicosanoids are potent bioactive lipids generated from arachidonic acid and play an important role in the initiation and progression of inflammation by acting as potent vasoconstrictors and enhancing permeability. The overarching goal of Paruchuri’s lab is to understand their signaling and targeting them towards obtaining novel therapies for various inflammatory disorders. Her work has been supported by NIH (K99/R00, R15, RO1s) and AHA (Grant-in-Aid and Transformative Project Award) grants. She has published more than 60 peer-reviewed articles in the fields of physiology, cell biology and biochemistry. Dr. Paruchuri is currently a standing member of NIH's Innate Immunity and Inflammation (III) study section and many review committees of AHA .

     

    To know more about the research, please visit https://www.utoledo.edu/med/depts/physpharm/faculty/Paruchuri.html 

selected publications

full name

  • Sailaja Paruchuri

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Cumulative publications in Scholars@UToledo