Nezam Altorok
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Professor
Program Director, Internal Medicine
Associate Program Director, Rheumatology
Director, Internal Medicine Faculty Development , Medicine , College of Medicine and Life Sciences
Contact Info
Overview
overview
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The goal of the current application is to review my performance after 5 year of receiving the tenur rank.
Since my promotion to Associate Professor with tenur in the clinical educator track in 2019, I had significant contribution to the mission of the Clollege of Medicine and Life Sciences at the University of Toledo. I am passionate about bedside teaching and medical education.
- I was awarded the Golden apple teaching award by COMLS in 2019, 2020 and 2024.
- I received The Dean's award for teaching 2021
- I was inducted in the AoA honor society 2023
- I received the Departement of Internal Medicine teaching award in 2021 and 2023.
Currently, I serve the the Director of Internal Medicine residency training program since July 1, 2024. Of note, I served as an Associate Program Director for the past 10 years. I oversee the training of 60 residents in three tracks, primary care, categorical and preliminary medicine.My long term career plan is to continue to (i) provide excellent clinical services to the community of Nothwest Ohio, (ii) provide excellent teaching for our students and residents, (iii) assist my faculty colleagues in providing excellent teaching for our learners. I think promotion to Professor will assist me in reaching these goals.
Publications
selected publications
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Article (Faculty180)
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20241,25-dihydroxyvitamin D mediated hypercalcemia in seminoma. The American journal of the medical sciences.
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2024Impact of Malnutrition on the Outcomes in Patients Admitted with Heart Failure. Journal of clinical medicine. 13.
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2023The Burden of Cardiac Arrhythmias in Gout: A National Representative Database Study. Current problems in cardiology. 48:101437.
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2023The Use of Methotrexate to Treat Peripheral Edema Caused by Spondyloarthropathy. American journal of therapeutics. 30:e403-e405.
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2022Balanced Crystalloids versus Normal Saline in Adults with Sepsis: A Comprehensive Systematic Review and Meta-Analysis. Journal of clinical medicine. 11.
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2022Leflunomide-Associated Pancytopenia. American journal of therapeutics.
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2022Subacute Cutaneous Lupus as a Paraneoplastic Manifestation of Non-Hodgkin Lymphoma. Journal of investigative medicine high impact case reports. 10:23247096211063066.
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2021Colchicine Treatment in SARS-CoV-2 Infection: A Systematic Review and Meta-Analysis. American journal of therapeutics. 29:e95-e98.
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2020Epigenetics and systemic sclerosis: An answer to disease onset and evolution?. European journal of rheumatology. 7:S147-S156.
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2020Ultrasound-mediated topical delivery of econazole nitrate with potential for treating Raynaud's phenomenon. International journal of pharmaceutics. 580.
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2019Evaluation of topical econazole nitrate formulations with potential for treating Raynaud's phenomenon. Pharmaceutical development and technology. 24:689-699.
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2016Beneficial Role for Endothelin in Scleroderma Vasculopathy: inhibition of endothelial apoptosis by type B receptor signaling. Journal Of Scleroderma and Related Disorders.
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2016Isolation and Characterization of Systemic Sclerosis Vascular Smooth Muscle Cells; enhanced proliferation and apoptosis resistance. Journal Of Scleroderma and Related Disorders. Journal Of Scleroderma and Related Disorders.
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2014Genome-wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sjögren's syndrome. Arthritis and Rheumatism.
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2010Thrombotic thrombocytopenic purpura associated with anti-glomerular basement membrane disease. Nephrol Dial Transplant.
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Adalimumab-Associated Hemorrhagic Pericarditis. American journal of therapeutics. e630-e632.
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Atezolizumab-Associated Retiform Purpura. American journal of therapeutics. 31:e455.
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Cocaine-Associated Antiglomerular Basement Membrane Antibody Syndrome Successfully Treated With Plasmapheresis and Mycophenolate. American journal of therapeutics. 31:e445.
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MetS and cardiovascular risk factors among Palestinians of East Jerusalem. East Mediterr Health J.
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Predictors of remission in rheumatoid arthritis patients treated with biologics: a systematic review and meta-analysis. Clinical rheumatology. 41:3615-3627.
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Successful treatment of antisynthetase syndrome presenting as rhabdomyolysis with rituximab. Rheumatology international. 1125-1130.
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Article (Web of Science)
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2021Genome-wide DNA methylation pattern in systemic sclerosis microvascular endothelial cells: Identification of epigenetically affected key genes and pathways. JOURNAL OF SCLERODERMA AND RELATED DISORDERS.Full Text via DOI: 10.1177/23971983211033772
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2021Henoch-Schonlein Purpura Presenting as Upper Gastrointestinal Bleed in an Adult Patient. CUREUS. 13.Full Text via DOI: 10.7759/cureus.13879
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2020Ultrasound-mediated topical delivery of econazole nitrate with potential for treating Raynaud's phenomenon. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 580.Full Text via DOI: 10.1016/j.ijpharm.2020.119229 PMID: 32184178
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2019Evaluation of topical econazole nitrate formulations with potential for treating Raynaud's phenomenon. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY. 24:689-699.Full Text via DOI: 10.1080/10837450.2019.1578371 PMID: 30712434
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2018Patient-reported outcome instruments for assessing Raynaud's phenomenon in systemic sclerosis: A SCTC vascular working group report. JOURNAL OF SCLERODERMA AND RELATED DISORDERS. 3:249-252.Full Text via DOI: 10.1177/2397198318774307 PMID: 30705970
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2017Tendonitis and Tendon Rupture After Treatment With Rituximab: A Case Series. AMERICAN JOURNAL OF THERAPEUTICS. 24:E592-E595.Full Text via DOI: 10.1097/MJT.0000000000000591
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2017Tendonitis and Tendon Rupture After Treatment With Rituximab: A Case Series. AMERICAN JOURNAL OF THERAPEUTICS. 24:e592-e595.Full Text via DOI: 10.1097/mjt.0000000000000591
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2016Mycobacterium Avium Complex Septic Arthritis in a Patient Treated by Infliximab. AMERICAN JOURNAL OF THERAPEUTICS. 23:E1222-E1225.Full Text via DOI: 10.1097/MJT.0000000000000318
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2016Successful Treatment of ANCA-Associated Vasculitis in the Setting of Common Variable Immunodeficiency Using Rituximab. AMERICAN JOURNAL OF THERAPEUTICS. 23:E1239-E1245.Full Text via DOI: 10.1097/MJT.0000000000000323
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2016Mycobacterium Avium Complex Septic Arthritis in a Patient Treated by Infliximab. AMERICAN JOURNAL OF THERAPEUTICS. 23:e1222-e1225.Full Text via DOI: 10.1097/mjt.0000000000000318
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2016Successful Treatment of ANCA-Associated Vasculitis in the Setting of Common Variable Immunodeficiency Using Rituximab. AMERICAN JOURNAL OF THERAPEUTICS. 23:e1239-e1245.Full Text via DOI: 10.1097/mjt.0000000000000323
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2016The isolation and characterization of systemic sclerosis vascular smooth muscle cells: enhanced proliferation and apoptosis resistance. JOURNAL OF SCLERODERMA AND RELATED DISORDERS. 1:307-315.Full Text via DOI: 10.5301/jsrd.5000218
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2015Epigenetics, the holy grail in the pathogenesis of systemic sclerosis. RHEUMATOLOGY. 54:1759-1770.Full Text via DOI: 10.1093/rheumatology/keu155
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2015Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies. ANNALS OF THE RHEUMATIC DISEASES. 74:1612-1620.Full Text via DOI: 10.1136/annrheumdis-2014-205303
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2015Identification of potential genomic biomarkers for Sjogren's syndrome using data pooling of gene expression microarrays. RHEUMATOLOGY INTERNATIONAL. 35:829-836.Full Text via DOI: 10.1007/s00296-014-3152-6
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2014Genome-Wide DNA Methylation Patterns in Naive CD4+T Cells From Patients With Primary Sjogren's Syndrome. ARTHRITIS & RHEUMATOLOGY. 66:731-739.Full Text via DOI: 10.1002/art.38264
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2013Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients. JOURNAL OF AUTOIMMUNITY. 43:78-84.Full Text via DOI: 10.1016/j.jaut.2013.04.003
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2013Recommendations for Screening and Detection of Connective Tissue Disease–Associated Pulmonary Arterial Hypertension. ARTHRITIS AND RHEUMATISM. 65:3194-3201.Full Text via DOI: 10.1002/art.38172
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2010Thrombotic thrombocytopenic purpura associated with anti-glomerular basement membrane disease. NEPHROLOGY DIALYSIS TRANSPLANTATION. 25:3446-3449.Full Text via DOI: 10.1093/ndt/gfq437
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Book Chapter (Web of Science)
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2016Epigenetics in Bone and Joint Disorders. Medical Epigenetics. 295-314.Full Text via DOI: 10.1016/b978-0-12-803239-8.00017-x
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Case Study (Faculty180)
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2015IMAGES IN CLINICAL MEDICINE. Diffuse Soft-Tissue Calcinosis.. 9;373(2):173.
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2011
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Cavitary lung lesions in systemic lupus. 19(8):993-6.
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Chapter (Faculty180)
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2016Epigenetics in bone and joint disease. Medical Epigenetics. Academic Press.
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epigenetics of systemic sclerosis. Handbook of epigenetics and nutrition. Elsevier Academic Press.
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Vasculitis and other Arteriopathies. Lange Vascular and Endovascular Surgery. Lange .
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Epigenetics of systemic sclerosis. Epigenetics and Dermatology.
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epigenetics of systemic sclerosis. Handbook of epigenetics and nutrition.
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Editorial Material (Web of Science)
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2015Bacterial Endocarditis Complicated by Leukocytoclastic Vasculitis. AMERICAN JOURNAL OF THE MEDICAL SCIENCES. 500-500.
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2015Diffuse Soft-Tissue Calcinosis. NEW ENGLAND JOURNAL OF MEDICINE. 173-173.Full Text via DOI: 10.1056/NEJMicm1407238
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2015Bacterial Endocarditis Complicated by Leukocytoclastic Vasculitis. AMERICAN JOURNAL OF THE MEDICAL SCIENCES. 500.Full Text via DOI: 10.1097/maj.0000000000000459
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2015Diffuse Soft-Tissue Calcinosis. NEW ENGLAND JOURNAL OF MEDICINE. 173-173.Full Text via DOI: 10.1056/nejmicm1407238
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2014Role of Dual-Energy Computed Tomography Scan in Diagnosis of Gout. JCR-JOURNAL OF CLINICAL RHEUMATOLOGY. 447-447.Full Text via DOI: 10.1097/RHU.0000000000000184
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2014Role of Dual-Energy Computed Tomography Scan in Diagnosis of Gout. JCR-JOURNAL OF CLINICAL RHEUMATOLOGY. 447.Full Text via DOI: 10.1097/rhu.0000000000000184
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2011The Clinical Picture Genital lesions and acute urinary retention. CLEVELAND CLINIC JOURNAL OF MEDICINE. 151-152.Full Text via DOI: 10.3949/ccjm.78a.10071
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Letter (Web of Science)
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2020Adalimumab-Associated Hemorrhagic Pericarditis. AMERICAN JOURNAL OF THERAPEUTICS. e630-e632.Full Text via DOI: 10.1097/mjt.0000000000001019
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2019Additional tools to boost internal medicine residents' evaluations. INTERNATIONAL JOURNAL OF MEDICAL EDUCATION. 43-44.Full Text via DOI: 10.5116/ijme.5c6c.358f PMID: 30825870
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2017Successful Treatmen of Central Nervous System Vasculitis Associated with Relapsing Polychondritis With Cyclophosphamide. AMERICAN JOURNAL OF THE MEDICAL SCIENCES. 495-497.
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2017Successful Treatment of Central Nervous System Vasculitis Associated with Relapsing Polychondritis With Cyclophosphamide. AMERICAN JOURNAL OF THE MEDICAL SCIENCES. 495-497.Full Text via DOI: 10.1016/j.amjms.2016.11.023
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2016Recurrent Kawasaki Disease: Mind the Age, But It Does Not Matter. JCR-JOURNAL OF CLINICAL RHEUMATOLOGY. 223-224.Full Text via DOI: 10.1097/RHU.0000000000000411
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2016Recurrent Kawasaki Disease. JCR-JOURNAL OF CLINICAL RHEUMATOLOGY. 223-224.Full Text via DOI: 10.1097/rhu.0000000000000411
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Meeting Abstract (Web of Science)
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2018
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2016
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2015Cell-Free Circulating DNA in Systemic Sclerosis: Increased Levels and Global Cytosine Hypomethylation. ARTHRITIS & RHEUMATOLOGY.
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2015
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2015Isolation and Initial Characterization of Dermal Vascular Smooth Muscle Cells in Systemic Sclerosis. ARTHRITIS & RHEUMATOLOGY.
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Review (Faculty180)
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Review Article (Web of Science)
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2020Epigenetics and systemic sclerosis: An answer to disease onset and evolution?. EUROPEAN JOURNAL OF RHEUMATOLOGY. S147-S156.Full Text via DOI: 10.5152/eurjrheum.2020.19112 PMID: 32697935
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2018Successful treatment of antisynthetase syndrome presenting as rhabdomyolysis with rituximab. RHEUMATOLOGY INTERNATIONAL. 1125-1130.Full Text via DOI: 10.1007/s00296-018-4025-1
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2015Epigenetics and systemic sclerosis. SEMINARS IN IMMUNOPATHOLOGY. 453-462.Full Text via DOI: 10.1007/s00281-015-0504-6
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2014Endothelial dysfunction in systemic sclerosis. CURRENT OPINION IN RHEUMATOLOGY. 615-620.Full Text via DOI: 10.1097/BOR.0000000000000112
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2014Endothelial dysfunction in systemic sclerosis. CURRENT OPINION IN RHEUMATOLOGY. 615-620.Full Text via DOI: 10.1097/bor.0000000000000112
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2014Screening and diagnostic modalities for connective tissue disease-associated pulmonary arterial hypertension: A systematic review. Seminars in Arthritis and Rheumatism. 536-541.Full Text via DOI: 10.1016/j.semarthrit.2013.08.002
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2013Epigenetics in the pathogenesis of systemic lupus erythematosus. CURRENT OPINION IN RHEUMATOLOGY. 569-576.Full Text via DOI: 10.1097/bor.0b013e328364206f
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Contact
full name
- Nezam Altorok