Eisenmann, Kathryn M

Kathryn M Eisenmann
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Positions

Professor, Biochemistry and Cancer Biology , College of Medicine and Life Sciences

Contact Info

Kathryn.Eisenmann@utoledo.edu

http://www.utoledo.edu/med/depts/cancer-biology/faculty/eisenmann.html

selected publications

Article (Faculty180)
- 2023
  
  Impact of COVID-19 on Clinical Productivity at the University of Toledo Medical Center Specialty Care Clinics. . Translation: The University of Toledo Journal of Medical Sciences. 599.
- 2022
  
  New Targets in the Glioblastoma Tumor Microtube Multiverse: Emerging Roles for the TGF-beta/TSP1 Signaling Axis. Neuro-Oncology.
- 2022
  
  New targets in the glioblastoma tumor microtube multiverse: Emerging roles for the TGF-β/TSP1 signaling axis
- 2009
  
  5q--myelodysplastic syndromes: chromosome 5q genes direct a tumor-suppression network sensing actin dynamics
- 2007
  
  T cell responses in mammalian diaphanous-related formin mDia1 knock-out mice
- Miniature Non‑thermal Plasma Induced Cell Cycle Arrest and Apoptosis in Lung Carcinoma Cells. Plasma Chemistry and Plasma Processing.
- Mitogen-activated protein kinase pathway-dependent tumor-specific survival signaling in melanoma cells through inactivation of the proapoptotic protein bad
- The role of formins in human disease. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research. 1803:226.
Article (Web of Science)
- 2019
  
  Miniature Non-thermal Plasma Induced Cell Cycle Arrest and Apoptosis in Lung Carcinoma Cells. PLASMA CHEMISTRY AND PLASMA PROCESSING. 40:99-117.
  Full Text via DOI: 10.1007/s11090-019-10037-2
- 2019
  
  Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres. CANCERS. 11.
  Full Text via DOI: 10.3390/cancers11030392 PMID: 30897774
- 2018
  
  Bax/Tubulin/Epithelial-Mesenchymal Pathways Determine the Efficacy of Silybin Analog HM015k in Colorectal Cancer Cell Growth and Metastasis. FRONTIERS IN PHARMACOLOGY. 9.
  Full Text via DOI: 10.3389/fphar.2018.00520
- 2018
  
  Differential Toxicity of mDia Formin-Directed Functional Agonists and Antagonists in Developing Zebrafish. FRONTIERS IN PHARMACOLOGY. 9.
  Full Text via DOI: 10.3389/fphar.2018.00340
- 2018
  
  Carcinoma associated fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2). PLOS ONE. 13.
  Full Text via DOI: 10.1371/journal.pone.0195278
- 2017
  
  Investigation of non-thermal plasma effects on lung cancer cells within 3D collagen matrices. JOURNAL OF PHYSICS D-APPLIED PHYSICS. 50.
  Full Text via DOI: 10.1088/1361-6463/aa7b10
- 2017
  
  mDia2 and CXCL12/CXCR4 chemokine signaling intersect to drive tumor cell amoeboid morphological transitions. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 484:255-261.
  Full Text via DOI: 10.1016/j.bbrc.2017.01.087
- 2017
  
  Miniature Dielectric Barrier Discharge Nonthermal Plasma Induces Apoptosis in Lung Cancer Cells and Inhibits Cell Migration. BIOMED RESEARCH INTERNATIONAL.
  Full Text via DOI: 10.1155/2017/8058307
- 2016
  
  SMIFH2-mediated mDia formin functional inhibition potentiates chemotherapeutic targeting of human ovarian cancer spheroids. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 472:33-39.
  Full Text via DOI: 10.1016/j.bbrc.2016.02.049
- 2015
  
  Small-molecule agonists of mammalian Diaphanous-related (mDia) formins reveal an effective glioblastoma anti-invasion strategy. MOLECULAR BIOLOGY OF THE CELL. 26:3704-3718.
  Full Text via DOI: 10.1091/mbc.E14-11-1502
- 2015
  
  High-calorie diet exacerbates prostate neoplasia in mice with haploinsufficiency of Pten tumor suppressor gene. MOLECULAR METABOLISM. 4:186-198.
  Full Text via DOI: 10.1016/j.molmet.2014.12.011
- 2015
  
  Small-molecule agonists of mammalian Diaphanous–related (mDia) formins reveal an effective glioblastoma anti-invasion strategy. MOLECULAR BIOLOGY OF THE CELL. 26:3704-3718.
  Full Text via DOI: 10.1091/mbc.e14-11-1502
- 2014
  
  An mDia2/ROCK Signaling Axis Regulates Invasive Egress from Epithelial Ovarian Cancer Spheroids. PLOS ONE. 9.
  Full Text via DOI: 10.1371/journal.pone.0090371
- 2013
  
  A microwave-assisted solution combustion synthesis to produce europium-doped calcium phosphate nanowhiskers for bioimaging applications. ACTA BIOMATERIALIA. 9:8422-8432.
  Full Text via DOI: 10.1016/j.actbio.2013.05.033
- 2012
  
  Dia-Interacting Protein (DIP) Imposes Migratory Plasticity in mDia2-Dependent Tumor Cells in Three-Dimensional Matrices. PLOS ONE. 7.
  Full Text via DOI: 10.1371/journal.pone.0045085
- 2007
  
  Dia-Interacting Protein Modulates Formin-Mediated Actin Assembly at the Cell Cortex. CURRENT BIOLOGY. 17:579-591.
  Full Text via DOI: 10.1016/j.cub.2007.03.024
- 2007
  
  Myeloproliferative Defects following Targeting of the Drf1 Gene Encoding the Mammalian Diaphanous–Related Formin mDia1. CANCER RESEARCH. 67:7565-7571.
  Full Text via DOI: 10.1158/0008-5472.can-07-1467
- 2007
  
  T Cell Responses in Mammalian Diaphanous-related Formin mDia1 Knock-out Mice. JOURNAL OF BIOLOGICAL CHEMISTRY. 282:25152-25158.
  Full Text via DOI: 10.1074/jbc.m703243200
- 2007
  
  mDia2 regulates actin and focal adhesion dynamics and organization in the lamella for efficient epithelial cell migration. JOURNAL OF CELL SCIENCE. 120:3475-3487.
  Full Text via DOI: 10.1242/jcs.006049
- 2001
  
  Regulation of Akt/PKB Activation by Tyrosine Phosphorylation. JOURNAL OF BIOLOGICAL CHEMISTRY. 276:31858-31862.
  Full Text via DOI: 10.1074/jbc.c100271200
- 1999
  
  Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas. NATURE CELL BIOLOGY. 1:507-513.
  Full Text via DOI: 10.1038/70302
Conference Poster (Faculty180)
- Targeting the mDia Formin-Assembled Cytoskeleton is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres
Meeting Abstract (Web of Science)
- 2018
  
  TARGETING THE FORMIN-DIRECTED CYTOSKELETON WITH SMALL MOLECULE AGONISTS BLOCKS GLIOBLASTOMA PATIENT-DERIVED NEUROSPHERE INVASION. NEURO-ONCOLOGY. 91-91.
- 2016
  
  Abstract 5068: Carcinoma-associated fibroblast-derived CXCL12 enhances MDA-MB-231 tumor cell migration though mDia2 formin suppression
  Full Text via DOI: 10.1158/1538-7445.am2016-5068
- 2013
  
  A Rho-directed ROCK:mDia2 signaling axis drives morphological plasticity and invasive transitions in EOC spheroids. CANCER RESEARCH.
  Full Text via DOI: 10.1158/1538-7445.AM2013-4918
- 2013
  
  Abstract 4918: A Rho-directed ROCK:mDia2 signaling axis drives morphological plasticity and invasive transitions in EOC spheroids.
  Full Text via DOI: 10.1158/1538-7445.am2013-4918
- 2012
  
  A role for mDia formins in epithelial ovarian cancer spheroid invasion. CANCER RESEARCH.
  Full Text via DOI: 10.1158/1538-7445.AM2012-484
- 2012
  
  Abstract 484: A role for mDia formins in epithelial ovarian cancer spheroid invasion
  Full Text via DOI: 10.1158/1538-7445.am2012-484
Review Article (Web of Science)
- 2010
  
  The role of formins in human disease. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. 226-233.
  Full Text via DOI: 10.1016/j.bbamcr.2009.11.006
- 2009
  
  5q– myelodysplastic syndromes: chromosome 5q genes direct a tumor-suppression network sensing actin dynamics. ONCOGENE. 3429-3441.
  Full Text via DOI: 10.1038/onc.2009.207

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Kathryn M Eisenmann

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