Ivana L. DeLaSerna
- Associate Professor, Biochemistry and Cancer Biology , College of Medicine and Life Sciences
Publications
selected publications
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Article (Faculty180)
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2025Ablation of the Evolutionarily Acquired Functions of the Gene Increases Metabolic Capacity and Reduces Obesity. Life (Basel, Switzerland). 15.
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2025Death-ision: the link between cellular resilience and cancer resistance to treatments. Molecular cancer. 24:144.
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2025Epigenetic Histone β-Hydroxybutyrylation Contributes to Renoprotection by β-Hydroxybutyrate in the Dahl Rat. Hypertension (Dallas, Tex. : 1979).
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2024
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2023Epigenetic and pharmacological control of pigmentation via Bromodomain Protein 9 (BRD9). Pigment cell & melanoma research. 36:19-32.
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2023Eutherian-Specific Functions of BetaM Acquired through Gene Co-Option in the Regulation of MyoD Expression. Life (Basel, Switzerland). 13.
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2022
SWI/SNF Chromatin Remodeling Enzymes in Melanoma.
. Epigenomes. 18. -
2022SWI/SNF Chromatin Remodeling Enzymes in Melanoma. Epigenomes. 6.
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2019BAF60A mediates interactions between the microphthalmia-associated transcription factor and the BRG1-containing SWI/SNF complex during melanocyte differentiation. Journal of cellular physiology. 234:11780.
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2019
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2019SETD7 in cardiomyocyte differentiation and cardiac function. Stem cell investigation. 6:29.
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2017
BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation
. Nucleic acids research. 45:6442. -
2015Impact of ATP1B4 Gene Co-option on Perinatal Development of Placental Mammals. The FASEB Journal. 29:684.
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2015MITF interacts with the SWI/SNF subunit, BRG1, to promote GATA4 expression in cardiac hypertrophy. Journal of molecular and cellular cardiology. 88:101.
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2015
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2014Modulation of BRAHMA expression by the mitogen-activated protein kinase/extracellular signal regulated kinase pathway is associated with changes in melanoma proliferation. Archives of biochemistry and biophysics. 563:125.
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2014Role of miR-10b in B-Raf (V600E)-induced melanomagenesis. Pigment Cell & Melanoma Research. 27:1183.
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2014SWI/SNF chromatin remodeling enzymes in melanocyte differentiation and melanoma. Critical Reviews™ in Eukaryotic Gene Expression. 24.
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2014SWI/SNF chromatin remodeling enzymes in melanocyte differentiation and melanoma. Critical reviews in eukaryotic gene expression. 24:151-61.
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2014The role of BRD4 in melanogenesis: P098. Pigment Cell & Melanoma Research. 27.
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2014To investigate the role of BAF60A in melanocyte differentiation: CS30. Pigment Cell & Melanoma Research. 27.
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2013BRG 1 promotes survival of UV-irradiated melanoma cells by cooperating with MITF to activate the melanoma inhibitor of apoptosis gene. Pigment cell & melanoma research. 26:377.
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2013CEBPG exhibits allele-specific expression in human bronchial epithelial cells. Gene regulation and systems biology. 7:GRSB.
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2013Enhanced SWI/SNF enzyme recruitment and chromatin remodeling on fetal cardiac gene promoters is associated with cardiac hypertrophy in a genetic rat model of hypertension. Journal of cellular physiology. 228:2337.
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2013PBAF chromatin remodeling complexes promote p53 target gene expression in response to ultraviolet radiation: 58. Pigment Cell & Melanoma Research. 26.
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2013Protein arginine N-methyltransferase-5 (PRMT5) in melanocyte differentiation: 34. Pigment Cell & Melanoma Research. 26.
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2013Role of SWI/SNF enzymes in the repair of UV-induced DNA damage. Pigment Cell & Melanoma Research. 26.
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2013SWI/SNF chromatin remodeling enzymes are associated with cardiac hypertrophy in a genetic rat model of hypertension. Journal of cellular physiology. 228:2337.
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2013SWI/SNF enzymes in the activation of melanin synthesis and prevention of UV-induced DNA damage through MC1R signaling. Pigment Cell & Melanoma Research. 26.
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2013SWI/SNF enzymes promote SOX10-mediated activation of myelin gene expression. PLoS One. 8:e69037.
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2013Synergistic activation of melanocyte specific gene expression by MITF and SOX10 involves recruitment of SWI/SNF chromatin remodeling enzymes. Pigment Cell & Melanoma Research. 26.
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2012A Micro-RNA Connection in-Mediated Premature Senescence of Human Melanocytes. International journal of cell biology. 2012.
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2012SWI/SNF chromatin remodeling enzymes in the response to ultraviolet radiation. Pigment Cell & Melanoma Research. 25.
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2010
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2010ATP dependent chromatin remodeling enzymes in embryonic stem cells. Stem Cell Reviews and Reports. 6:62.
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2010
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2010SWI/SNF chromatin remodeling enzymes in melanocyte differentiation: 64. Pigment Cell & Melanoma Research. 23.
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2010SWItching on the transcriptional circuitry in melanoma. Epigenetics. 5:469.
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2010The obesity-associated Fto gene is a transcriptional coactivator. Biochemical and biophysical research communications. 401:390.
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2009Chromatin remodeling in embryonic stem cells: regulating the balance between pluripotency and differentiation. Journal of cellular physiology. 219:1.
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2009Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma. Pigment Cell & Melanoma Research. 22:512.
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2009Oncogenic BRAF (V600E) induced de-regulation of SWI/SNF chromatin remodeling enzymes. Pigment Cell & Melanoma Research. 22:895.
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2007The Role of SWI/SNF Chromatin Remodeling Enzymes in Melanocyte and Melanoma Gene Expression. Pigment Cell Research. 20:558.
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2006Chromatin remodelling in mammalian differentiation: lessons from ATP-dependent remodellers. Nature Reviews Genetics. 7:461.
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2006The microphthalmia-associated transcription factor requires SWI/SNF enzymes to activate melanocyte-specific genes. Journal of Biological Chemistry. 281:20233.
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2005MyoD targets chromatin remodeling complexes to the myogenin locus prior to forming a stable DNA-bound complex. Molecular and cellular biology. 25:3997.
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2004BRCA1 interacts with dominant negative SWI/SNF enzymes without affecting homologous recombination or radiation-induced gene activation of p21 or Mdm2. Journal of cellular biochemistry. 91:987.
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2004Repositioning of muscle-specific genes relative to the periphery of SC-35 domains during skeletal myogenesis. Molecular biology of the cell. 15:197.
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2002Involvement of hSWI/SNF in homologous recombination. Biochemistry and Cell Biology. 80:384.
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2002The myogenic basic helix-loop-helix family of transcription factors shows similar requirements for SWI/SNF chromatin remodeling enzymes during muscle differentiation in culture. Journal of Biological Chemistry. 277:33818.
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2002Unfolding heterochromatin for replication. nature genetics. 32:560.
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2001
Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation
. Nature genetics. 27:187. -
2001
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2001Mammalian SWI/SNF complexes are required for MyoD-mediated muscle differentiation. BIOCHEMISTRY AND CELL BIOLOGY. 79:370.
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2000Mammalian SWI-SNF complexes contribute to activation of the hsp70 gene. Molecular and cellular biology. 20:2839.
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2000Non-coordinate regulation of 5S rRNA genes and the gene encoding the 5S rRNA-binding ribosomal protein homolog in Neurospora crassa. Molecular and General Genetics MGG. 263:987.
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Article (Web of Science)
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2020Role of the CXCR4-LASP1 Axis in the Stabilization of Snail1 in Triple-Negative Breast Cancer. CANCERS. 12.Full Text via DOI: 10.3390/cancers12092372 PMID: 32825729
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2020Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation. EPIGENETICS & CHROMATIN. 13.Full Text via DOI: 10.1186/s13072-020-00333-z PMID: 32151278
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2019BAF60A mediates interactions between the microphthalmia-associated transcription factor and the BRG1-containing SWI/SNF complex during melanocyte differentiation. JOURNAL OF CELLULAR PHYSIOLOGY. 234:11777-11791.Full Text via DOI: 10.1002/jcp.27840 PMID: 30515787
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2019Critical role of miR-10b in B-Raf(V600E) dependent anchorage independent growth and invasion of melanoma cells. PLOS ONE. 14.Full Text via DOI: 10.1371/journal.pone.0204387 PMID: 30995246
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2017BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation. NUCLEIC ACIDS RESEARCH. 45:6442-6458.Full Text via DOI: 10.1093/nar/gkx259
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2015MITF interacts with the SWI/SNF subunit, BRG1, to promote GATA4 expression in cardiac hypertrophy. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 88:101-110.Full Text via DOI: 10.1016/j.yjmcc.2015.09.010
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2015RKIP Inhibits Local Breast Cancer Invasion by Antagonizing the Transcriptional Activation of MMP13. PLOS ONE. 10.Full Text via DOI: 10.1371/journal.pone.0134494
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2015RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration. ONCOTARGET. 6:39050-39061.Full Text via DOI: 10.18632/oncotarget.5176
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2014Modulation of BRAHMA expression by the mitogen-activated protein kinase/extracellular signal regulated kinase pathway is associated with changes in melanoma proliferation. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 563:125-135.Full Text via DOI: 10.1016/j.abb.2014.07.004
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2014SWI/SNF Chromatin Remodeling Enzymes in Melanocyte Differentiation and Melanoma. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION. 24:151-161.Full Text via DOI: 10.1615/critreveukaryotgeneexpr.2014007882
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2013SWI/SNF Chromatin Remodeling Enzymes are Associated with Cardiac Hypertrophy in a Genetic Rat Model of Hypertension. JOURNAL OF CELLULAR PHYSIOLOGY. 228:2337-2342.Full Text via DOI: 10.1002/jcp.24404
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2013SWI/SNF Enzymes Promote SOX10-Mediated Activation of Myelin Gene Expression. PLOS ONE. 8.Full Text via DOI: 10.1371/journal.pone.0069037
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2013BRG1 promotes survival of UV-irradiated melanoma cells by cooperating with MITF to activate the melanoma inhibitor of apoptosis gene. PIGMENT CELL & MELANOMA RESEARCH. 26:377-391.Full Text via DOI: 10.1111/pcmr.12088
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2013CEBPG Exhibits Allele-Specific Expression in Human Bronchial Epithelial Cells. Gene Regulation and Systems Biology. 7:GRSB.S11879.Full Text via DOI: 10.4137/grsb.s11879
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2012Polycomb Protein EZH2 Regulates Tumor Invasion via the Transcriptional Repression of the Metastasis Suppressor RKIP in Breast and Prostate Cancer. CANCER RESEARCH. 72:3091-3104.Full Text via DOI: 10.1158/0008-5472.can-11-3546
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2010Modulation of extracellular matrix/adhesion molecule expression by BRG1 is associated with increased melanoma invasiveness. MOLECULAR CANCER. 9.Full Text via DOI: 10.1186/1476-4598-9-280
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2010The obesity-associated Fto gene is a transcriptional coactivator. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 401:390-395.Full Text via DOI: 10.1016/j.bbrc.2010.09.064
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2010SWItching on the transcriptional circuitry in melanoma. EPIGENETICS. 5.Full Text via DOI: 10.4161/epi.5.6.12315
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2010ATP Dependent Chromatin Remodeling Enzymes in Embryonic Stem Cells. STEM CELL REVIEWS AND REPORTS. 6:62-73.Full Text via DOI: 10.1007/s12015-010-9120-y
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2010Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma. ONCOGENE. 29:81-92.Full Text via DOI: 10.1038/onc.2009.304
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2006The Microphthalmia-associated Transcription Factor Requires SWI/SNF Enzymes to Activate Melanocyte-specific Genes. JOURNAL OF BIOLOGICAL CHEMISTRY. 281:20233-20241.Full Text via DOI: 10.1074/jbc.m512052200
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2005MyoD Targets Chromatin Remodeling Complexes to the Myogenin Locus Prior to Forming a Stable DNA-Bound Complex. MOLECULAR AND CELLULAR BIOLOGY. 25:3997-4009.Full Text via DOI: 10.1128/mcb.25.10.3997-4009.2005
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2004BRCA1 interacts with dominant negative SWI/SNF enzymes without affecting homologous recombination or radiation-induced gene activation of p21 or Mdm2. JOURNAL OF CELLULAR BIOCHEMISTRY. 91:987-998.Full Text via DOI: 10.1002/jcb.20003
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2004Repositioning of Muscle-specific Genes Relative to the Periphery of SC-35 Domains during Skeletal Myogenesis. MOLECULAR BIOLOGY OF THE CELL. 15:197-206.Full Text via DOI: 10.1091/mbc.e03-06-0388
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2002The Myogenic Basic Helix-Loop-Helix Family of Transcription Factors Shows Similar Requirements for SWI/SNF Chromatin Remodeling Enzymes during Muscle Differentiation in Culture. JOURNAL OF BIOLOGICAL CHEMISTRY. 277:33818-33824.Full Text via DOI: 10.1074/jbc.m205159200
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2001Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation. NATURE GENETICS. 27:187-190.Full Text via DOI: 10.1038/84826
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2001MyoD Can Induce Cell Cycle Arrest but Not Muscle Differentiation in the Presence of Dominant Negative SWI/SNF Chromatin Remodeling Enzymes. JOURNAL OF BIOLOGICAL CHEMISTRY. 276:41486-41491.Full Text via DOI: 10.1074/jbc.m107281200
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2000Mammalian SWI-SNF Complexes Contribute to Activation of the hsp70 Gene. MOLECULAR AND CELLULAR BIOLOGY. 20:2839-2851.Full Text via DOI: 10.1128/mcb.20.8.2839-2851.2000
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2000Non-coordinate regulation of 5S rRNA genes and the gene encoding the 5S rRNA-binding ribosomal protein homolog in Neurospora crassa. Molecular and General Genetics MGG. 263:987-994.Full Text via DOI: 10.1007/pl00008699
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1999Carbon Regulation of Ribosomal Genes in Neurospora crassa Occurs by a Mechanism Which Does Not Require Cre-1, the Homologue of the Aspergillus Carbon Catabolite Repressor, CreA. Fungal Genetics and Biology. 26:253-269.Full Text via DOI: 10.1006/fgbi.1999.1121
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Conference Poster (Faculty180)
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Correction (Web of Science)
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2016RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration (vol 6, pg 39050, 2015). ONCOTARGET. 26925-26925.Full Text via DOI: 10.18632/oncotarget.9139
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Editorial Material (Web of Science)
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2002Unfolding heterochromatin for replication. NATURE GENETICS. 560-562.Full Text via DOI: 10.1038/ng1202-560
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Other Scholarly Work (Faculty180)
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2012Bromodomain Containing Protein (BRD9) Expression in Melanoma . Medical Student Research.
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Proceedings (Faculty180)
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Review Article (Web of Science)
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2009Chromatin Remodeling in Embryonic Stem Cells: Regulating the Balance Between Pluripotency and Differentiation. JOURNAL OF CELLULAR PHYSIOLOGY. 1-7.Full Text via DOI: 10.1002/jcp.21654
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2006Chromatin remodelling in mammalian differentiation: lessons from ATP-dependent remodellers. Nature Reviews Genetics. 461-473.Full Text via DOI: 10.1038/nrg1882
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Contact
full name
- Ivana L. DeLaSerna
visualizations
Cumulative publications in Scholars@UToledo
