Halim Ayan
- Associate Professor, Bioengineering , College of Engineering
Contact Info
Overview
overview
-
Halim Ayan received the B.Sc. (summa cum laude) degree in mechanical engineering from Ege University, Izmir, Turkey, in 2001, and the Ph.D. degree in mechanical engineering and mechanics from Drexel University, Philadelphia, PA, USA, in 2009. His doctoral study was on development and characterization of a novel non‐thermal atmospheric pressure dielectric barrier discharge plasma with nanosecond rise time high voltage pulses for medical and biological applications.
From 2009 to 2012, Dr. Ayan was an Assistant Professor with the Department of Engineering and Physics, Murray State University, Murray, KY, USA and Department of Mechanical Engineering, University of Kentucky, Paducah, KY USA. He has been an Assistant Professor from 2012 to 2018, and since 2018 an Associate Professor with the Department of Bioengineering and the Department of Mechanical, Industrial and Manufacturing Engineering, University of Toledo, Toledo, OH, USA, where he has been teaching both bioengineering and mechanical engineering courses.
Dr. Ayan’s current research interests include discharge physics and biomedical applications of atmospheric pressure dielectric-barrier discharge such as sterilization and cancer treatment. He has received 2 NSF, 1 NIH, and 2 USAF-MDA research grants; published 1 book, 2 book chapters, 18 peer-reviewed journal articles, and 2 patents; and delivered several podium presentations at international conferences. Dr. Ayan serves as a reviewer for several internationally recognized journals and is a founding member of the International Society of Plasma Medicine and the International Society for Biofabrication.
Publications
selected publications
-
Article (Web of Science)
-
2019Miniature Non-thermal Plasma Induced Cell Cycle Arrest and Apoptosis in Lung Carcinoma Cells. PLASMA CHEMISTRY AND PLASMA PROCESSING. 40:99-117.Full Text via DOI: 10.1007/s11090-019-10037-2
-
2018Mathematical Modelling of the Effects of Plasma Treatment on the Diffusivity of Biofilm. APPLIED SCIENCES-BASEL. 8.Full Text via DOI: 10.3390/app8101729
-
2018Antimicrobial Effectiveness of Regular Dielectric- Barrier Discharge (DBD) and Jet DBD on the Viability of
Pseudomonas aeruginosa . IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES. 2:68-76.Full Text via DOI: 10.1109/tps.2017.2748982 -
2017Equiaxial Strain Modulates Adipose-derived Stem Cell Differentiation within 3D Biphasic Scaffolds towards Annulus Fibrosus. SCIENTIFIC REPORTS. 7.Full Text via DOI: 10.1038/s41598-017-13240-3
-
2017Investigation of non-thermal plasma effects on lung cancer cells within 3D collagen matrices. JOURNAL OF PHYSICS D-APPLIED PHYSICS. 50.Full Text via DOI: 10.1088/1361-6463/aa7b10
-
2017Miniature Dielectric Barrier Discharge Nonthermal Plasma Induces Apoptosis in Lung Cancer Cells and Inhibits Cell Migration. BIOMED RESEARCH INTERNATIONAL.Full Text via DOI: 10.1155/2017/8058307
-
2017Sterilization of Biofilm on a Titanium Surface Using a Combination of Nonthermal Plasma and Chlorhexidine Digluconate. BIOMED RESEARCH INTERNATIONAL.Full Text via DOI: 10.1155/2017/6085741
-
2015Exogenous nitric oxide (NO) generated by NO-plasma treatment modulates osteoprogenitor cells early differentiation. JOURNAL OF PHYSICS D-APPLIED PHYSICS. 48.Full Text via DOI: 10.1088/0022-3727/48/34/345401
-
2015Localized surface functionalization of polycaprolactone with atmospheric-pressure microplasma jet. Biomedical Physics & Engineering Express. 1:025002.Full Text via DOI: 10.1088/2057-1976/1/2/025002
-
2011Development of a cold atmospheric pressure microplasma jet for freeform cell printing. APPLIED PHYSICS LETTERS. 99:111502.Full Text via DOI: 10.1063/1.3638062
-
2009Application of nanosecond-pulsed dielectric barrier discharge for biomedical treatment of topographically non-uniform surfaces. JOURNAL OF PHYSICS D-APPLIED PHYSICS. 42:125202.Full Text via DOI: 10.1088/0022-3727/42/12/125202
-
2009Heating Effect of Dielectric Barrier Discharges for Direct Medical Treatment. IEEE TRANSACTIONS ON PLASMA SCIENCE. 37:113-120.Full Text via DOI: 10.1109/tps.2008.2006899
-
2008Effect of Dielectric Barrier Discharge Plasma on the Attachment and Proliferation of Osteoblasts Cultured over Poly(ɛ-caprolactone) Scaffolds. Plasma Processes and Polymers. 5:58-66.Full Text via DOI: 10.1002/ppap.200700041
-
2008Nanosecond-Pulsed Uniform Dielectric-Barrier Discharge. IEEE TRANSACTIONS ON PLASMA SCIENCE. 36:504-508.Full Text via DOI: 10.1109/tps.2008.917947
-
2007Comparison of Direct and Indirect Effects of Non-Thermal Atmospheric-Pressure Plasma on Bacteria. Plasma Processes and Polymers. 4:370-375.Full Text via DOI: 10.1002/ppap.200600217
-
2006Blood Coagulation and Living Tissue Sterilization by Floating-Electrode Dielectric Barrier Discharge in Air. PLASMA CHEMISTRY AND PLASMA PROCESSING. 26:425-442.Full Text via DOI: 10.1007/s11090-006-9024-4
-
-
Correction (Web of Science)
-
2008Effect of Dielectric Barrier Discharge Plasma on the Attachment and Proliferation of Osteoblasts Cultured over Poly(ɛ-caprolactone) Scaffolds. Plasma Processes and Polymers. 397-397.Full Text via DOI: 10.1002/ppap.200800047
-
-
Meeting Abstract (Web of Science)
-
2017NON-THERMAL PLASMA IN CONJUNCTION WITH CHLORHEXIDINE (CHX) DIGLUCONATE STERILIZE THE BIOFILM CONTAMINATED TITANIUM SURFACE. 2017 IEEE INTERNATIONAL CONFERENCE ON PLASMA SCIENCE (ICOPS).
-
2017NON-THERMAL PLASMA IN CONJUNCTION WITH CHLORHEXIDINE (CHX) DIGLUCONATE STERILIZE THE BIOFILM CONTAMINATED TITANIUM SURFACE. 2017 IEEE INTERNATIONAL CONFERENCE ON PLASMA SCIENCE (ICOPS).
-
2015STERILIZATION OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS WITH DIELECTRIC BARRIER DISCHARGE. 2015 42ND IEEE INTERNATIONAL CONFERENCE ON PLASMA SCIENCES (ICOPS).
-
-
Proceedings Paper (Web of Science)
-
2007Functionalization of polymers using n 2 pulsed dielectric barrier dischargeFull Text via DOI: 10.1109/ppps.2007.4651910
-
Review Article (Web of Science)
-
2019Application of Non-Thermal Plasma on Biofilm: A Review. APPLIED SCIENCES-BASEL.Full Text via DOI: 10.3390/app9173548
-
Contact
full name
- Halim Ayan