Fedorov, Alexei

Alexei Fedorov
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Positions

Associate Professor
Vice Director of Bioinformatics and Proteomics/Genomics Program, Medicine , College of Medicine and Life Sciences

Contact Info

Alexei.Fedorov@utoledo.edu

selected publications

Article (Faculty180)
- 2020
  
  Genomic landscape of the signals of positive natural selection in populations of Northern Eurasia: A view from Northern Russia. PLoS One. 15:e0228778.
- 2020
  
  Global Picture of Genetic Relatedness and the Evolution of Humankind. Biology (Basel). 9.
- 2018
  
  1000 human genomes carry widespread signatures of GC biased gene conversion. BMC Genomics. 19:256.
- 2017
  
  Intricacies in arrangement of SNP haplotypes suggest "Great Admixture" that created modern humans. BMC Genomics. 18:433.
- 2015
  
  Inference of distant genetic relations in humans using "1000 genomes". Genome Biol Evol. 7:481-92.
- 2015
  
  Maruyama's allelic age revised by whole-genome GEMA simulations. Genomics. 105:282-7.
- 2011
  
  Critical association of ncRNA with introns. Nucleic Acids Res. 39:2357-66.
- 2011
  
  Genomic MRI--a public resource for studying sequence patterns within genomic DNA. J Vis Exp.
- 2011
  
  Mid-range inhomogeneity of eukaryotic genomes. ScientificWorldJournal. 11:842-54.
- 2008
  
  snoTARGET shows that human orphan snoRNA targets locate close to alternative splice junctions. Gene. 408:172-9.
- 2006
  
  Advances in the Exon-Intron Database (EID). Brief Bioinform. 7:178-85.
- 2005
  
  Puzzles of the human genome: Why do we need our introns?. Current Genomics. 6:589-595.
- 2003
  
  Large-scale comparison of intron positions in mammalian genes shows intron loss but no gain. Proc Natl Acad Sci U S A. 100:7158-62.
- 2002
  
  Do introns favor or avoid regions of amino acid conservation?. Mol Biol Evol. 19:521-252.
- 2002
  
  Regularities of context-dependent codon bias in eukaryotic genes. Nucleic Acids Res. 30:1192-7.
- 2001
  
  [In silico analysis of the restriction fragments length distribution in the human genome]. Genetika. 37:456-66.
- 2000
  
  EID: the Exon-Intron Database-an exhaustive database of protein-coding intron-containing genes. Nucleic Acids Res. 28:185-90.
- 1998
  
  Influence of exon duplication on intron and exon phase distribution. J Mol Evol. 46:263-71.
- 1994
  
  BSP FAMILY OF TANDEMLY REPEATED DNA-SEQUENCES OF BAIKAL COTTOID FISHES (COTTOIDEA). Molecular Biology. 28:282-288.
- 1994
  
  NEW METHOD OF NONRADIOACTIVE LABELING OF OLIGONUCLEOTIDES AND THEIR USE AS ALLELE-SPECIFIC PROBES FOR MUTATIONS CAUSING BETA-THALASSEMIA. Molecular Biology. 28:521-526.
- 1993
  
  DNA Taxoprint Analysis of Family Lacertidae Species. Molecular Biology. 27:883-890.
- 1992
  
  The T-->A mutation at position -30 of the beta-globin gene found in a Karachai patient with beta-thalassemia intermedia. Hemoglobin. 16:521-3.
- 1987
  
  MOLECULAR INVESTIGATION OF THALASSEMIA. 4. CLONING OF BETA-GLOBIN GENE OF BETA-THALASSEMIC PATIENT FROM AZERBAIJAN AND DETERMINATION OF A POINT MUTATION IN MINOR INTRON. Genetika. 23:228-238.
Article (Web of Science)
- 2020
  
  Global Picture of Genetic Relatedness and the Evolution of Humankind. BIOLOGY-BASEL. 9.
  Full Text via DOI: 10.3390/biology9110392 PMID: 33182715
- 2020
  
  Adapting Biased Gene Conversion theory to account for intensive GC-content deterioration in the human genome by novel mutations. PLOS ONE. 15.
  Full Text via DOI: 10.1371/journal.pone.0232167 PMID: 32353016
- 2020
  
  Genomic landscape of the signals of positive natural selection in populations of Northern Eurasia: A view from Northern Russia. PLOS ONE. 15.
  Full Text via DOI: 10.1371/journal.pone.0228778 PMID: 32023328
- 2018
  
  1000 human genomes carry widespread signatures of GC biased gene conversion. BMC GENOMICS. 19.
  Full Text via DOI: 10.1186/s12864-018-4593-1
- 2017
  
  Intricacies in arrangement of SNP haplotypes suggest "Great Admixture" that created modern humans. BMC GENOMICS. 18.
  Full Text via DOI: 10.1186/s12864-017-3776-5
- 2015
  
  Maruyama's allelic age revised by whole-genome GEMA simulations. GENOMICS. 105:282-287.
  Full Text via DOI: 10.1016/j.ygeno.2015.02.005
- 2015
  
  Inference of Distant Genetic Relations in Humans Using "1000 Genomes". GENOME BIOLOGY AND EVOLUTION. 7:481-492.
  Full Text via DOI: 10.1093/gbe/evv003
- 2014
  
  Bioinformatics analysis of plant orthologous introns: identification of an intronic tRNA-like sequence. GENE. 548:81-90.
  Full Text via DOI: 10.1016/j.gene.2014.07.012
- 2014
  
  Genome Evolution by Matrix Algorithms: Cellular Automata Approach to Population Genetics. GENOME BIOLOGY AND EVOLUTION. 6:988-999.
  Full Text via DOI: 10.1093/gbe/evu075
- 2013
  
  Vertebrate codon bias indicates a highly GC-rich ancestral genome. GENE. 519:113-119.
  Full Text via DOI: 10.1016/j.gene.2013.01.033
- 2012
  
  Exploiting mid-range DNA patterns for sequence classification: binary abstraction Markov models. NUCLEIC ACIDS RESEARCH. 40:4765-4773.
  Full Text via DOI: 10.1093/nar/gks154
- 2011
  
  Genomic MRI - a Public Resource for Studying Sequence Patterns within Genomic DNA. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS.
  Full Text via DOI: 10.3791/2663
- 2011
  
  Spliceosomal genes in the D. discoideum genome: a comparison with those in H. sapiens, D. melanogaster, A. thaliana and S. cerevisiae. PROTEIN & CELL. 2:395-409.
  Full Text via DOI: 10.1007/s13238-011-1052-z
- 2011
  
  Critical association of ncRNA with introns. NUCLEIC ACIDS RESEARCH. 39:2357-2366.
  Full Text via DOI: 10.1093/nar/gkq1080
- 2009
  
  The Peculiarities of Large Intron Splicing in Animals. PLOS ONE. 4.
  Full Text via DOI: 10.1371/journal.pone.0007853
- 2009
  
  Evolution of genomic sequence inhomogeneity at mid-range scales. BMC GENOMICS. 10.
  Full Text via DOI: 10.1186/1471-2164-10-513
- 2008
  
  Genomic mid-range inhomogeneity correlates with an abundance of RNA secondary structures. BMC GENOMICS. 9.
  Full Text via DOI: 10.1186/1471-2164-9-284
- 2008
  
  snoTARGET shows that human orphan snoRNA targets locate close to alternative splice junctions. GENE. 408:172-179.
  Full Text via DOI: 10.1016/j.gene.2007.10.037
Chapter (Faculty180)
- 1991
  
  The investigation of mutant genes and human normal polymorphism. Metabolism and enzymology of nucleic acids including gene and protein engineering. Slovak Academy of Sciences. 7.
Proceedings Paper (Web of Science)
- 2009
  
  Computation of putative targets for human and mouse snoRNAs, responsible for Prader-Willi Syndrome.. 2009 OHIO COLLABORATIVE CONFERENCE ON BIOINFORMATICS, PROCEEDINGS. 58-58.
  Full Text via DOI: 10.1109/OCCBIO.2009.36
- 2009
  
  Computation of Putative Targets for Human and Mouse snoRNAs, Responsible for Prader-Willi Syndrome
  Full Text via DOI: 10.1109/occbio.2009.36
Review Article (Web of Science)
- 2011
  
  Mid-Range Inhomogeneity of Eukaryotic Genomes. THESCIENTIFICWORLDJOURNAL. 842-854.
  Full Text via DOI: 10.1100/tsw.2011.82

full name

Alexei Fedorov

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