González-Seguel, Felipe; Summers, Louisa A; Fresenko, Lindsey E; Long, Douglas E; Scott, Logan N; Slone, Stacey A; Shankara Bhaktula, Srushan; Wen, Yuan; Miller, Benjamin F; Morris, Peter E; Salyer, Amy L; Kalema, Anna G; Montgomery-Yates, Ashley A; Dupont-Versteegden, Esther E; Mayer, Kirby P; TRACER study group Collaborators
description
Patients who survive admission to intensive care unit (ICU) for critical illness are at high risk of developing muscle atrophy and weakness, commonly diagnosed as ICU-acquired weakness (ICUAW). The development of ICUAW is closely linked to long-term symptoms and impairments known as post-intensive care syndrome (PICS). Despite heightened recognition of impairments, there is limited research supporting effective interventions to improve muscle and physical outcomes after hospital discharge. Prior to developing and testing interventions for ICU survivors, it is imperative to understand the trajectory of muscle and physical function recovery following an ICU stay. The purpose of this study is to longitudinally investigate skeletal muscle health and physical function outcomes after ICU admission.