Peterson, Jennifer M; Leclair, Valérie; Oyebode, Olumide E; Herzallah, Dema M; Nestor-Kalinoski, Andrea L; Morais, Jose; Zahedi, René P; Alamr, Mazen; Di Battista, John A; Hudson, Marie
description
Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of inflammatory muscle disorders of unknown etiology. It is postulated that mitochondrial dysfunction and protein aggregation in skeletal muscle contribute to myofiber degeneration. However, molecular pathways that lead to protein aggregation in skeletal muscle are not well defined.
