Unique Neural Circuit Connectivity of Mouse Proximal, Middle, and Distal Colon Defines Regional Colonic Motor Patterns Article (Faculty180)

cited authors

  • Nestor-Kalinoski, Andrea; Smith-Edwards, Kristen M; Meerschaert, Kimberly; Margiotta, Joseph F; Rajwa, Bartek; Davis, Brian M; Howard, Marthe J

description

  • Colonic motor patterns have been described by a number of different groups, but the neural connectivity and ganglion architecture supporting patterned motor activity have not been elucidated. Our goals were to describe quantitatively, by region, the structural architecture of the mouse enteric nervous system and use functional calcium imaging, pharmacology, and electrical stimulation to show regional underpinnings of different motor patterns.

publication date

  • 2022

start page

  • 309

end page

  • 337.e3

volume

  • 13