Golonka, Rachel M; Yeoh, Beng S; Saha, Piu; Gohara, Amira; Tummala, Ramakumar; Stepkowski, Stanislaw; Tiwari, Amit K; Joe, Bina; Gonzalez, Frank J; Gewirtz, Andrew T; Vijay-Kumar, Matam
description
HCC is the most common primary liver cancer and a leading cause of cancer-related mortality. Gut microbiota is a large collection of microbes, predominately bacteria, that harbor the gastrointestinal tract. Changes in gut microbiota that deviate from the native composition, that is, "dysbiosis," is proposed as a probable diagnostic biomarker and a risk factor for HCC. However, whether gut microbiota dysbiosis is a cause or a consequence of HCC is unknown.
