Hippocampal volume mediates the relationship between measures of pre-treatment cocaine use and within-treatment cocaine abstinence
Article (Faculty180)
Xu, Jiansong; Kober, Hedy; Wang, Xin; DeVito, Elise E E; Carroll, Kathleen M; Potenza, Marc N
description
Data suggest that the amygdala and hippocampus contribute to cocaine seeking and use, particularly following exposure to cocaine-related cues and contexts. Furthermore, indices of pre-treatment cocaine-use severity have been shown to correlate with treatment outcome in cocaine-dependent patients.