Activation of transient receptor potential vanilloid 1 decreases endothelial nitric oxide synthase phosphorylation at Thr497 by protein phosphatase 2B-dependent dephosphorylation of protein kinase C Article (Faculty180)

cited authors

  • Ching, L- C; Zhao, J- F; Su, K- H; Shyue, S- K; Hsu, C- P; Lu, T- M; Lin, S- J; Lee, T- S


  • We investigated the effects and underlying molecular mechanism of transient receptor potential vanilloid 1 (TRPV1), a calcium (Ca(2+) )-permeable non-selective cation channel, on phosphorylation of endothelial nitric oxide synthase (eNOS) at threonine 497 (Thr497) in bovine aortic endothelial cells (BAECs) and in mice.


publication date

  • 2013

published in

start page

  • 124

end page

  • 35


  • 209