Transient receptor potential vanilloid type 1 is vital for (-)-epigallocatechin-3-gallate mediated activation of endothelial nitric oxide synthase Article (Faculty180)

cited authors

  • Guo, Bei- C; Wei, Jeng; Su, Kuo- H; Chiang, A N; Zhao, Jin- F; Chen, Hsiang- Y; Shyue, Song- K; Lee, Tzong- S


  • Epigallocatechin-3-gallate (EGCG), the most abundant catechin of green tea, has beneficial effects on physiological functions of endothelial cells (ECs), yet the detailed mechanisms are not fully understood. In this study, we investigated the role of transient receptor potential vanilloid type 1 (TRPV1), a ligand-gated nonselective calcium channel, in EGCG-mediated endothelial nitric oxide (NO) synthase (eNOS) activation and angiogenesis.


publication date

  • 2015

published in

start page

  • 646

end page

  • 57


  • 59