Estrogen receptor α and aromatase polymorphisms affect risk, prognosis, and therapeutic outcome in men with castration-resistant prostate cancer treated with docetaxel-based therapy Article (Faculty180)

cited authors

  • Sissung, Tristan M; Danesi, Romano; Kirkland, C T; Baum, Caitlin E; Ockers, Sandra B; Stein, Erica V; Venzon, David; Price, Douglas K; Figg, William D


  • Reactive estrogen species cause genotoxicity and interfere with docetaxel-mediated tubulin polymerization resulting in shortened survival in men with castrate-resistant prostate cancer (CRPC).


publication date

  • 2011

start page

  • E368

end page

  • 72


  • 96