Woo, Sukyung; Gardner, E R; Chen, Xiaohong; Ockers, Sandra B; Baum, Caitlin E; Sissung, Tristan M; Price, Douglas K; Frye, Robin; Piekarz, Richard L; Bates, Susan E; Figg, William D
description
Romidepsin is a potent histone deacetylase inhibitor under clinical development. The objective of this study was to evaluate the effect of demographic, clinical, and pharmacogenetic covariates on the pharmacokinetics of romidepsin in patients with T-cell lymphoma.