The Anne Frank Assignment, which is the central focus of this chapter, uses the authentic case of a teenage girl for student teachers and other human services professionals to learn to apply human development theory by describing, explaining, and improving the human condition, whether it be a student in a classroom, a patient in a hospital, or a citizen living in a downtown community area. The purpose of the assignment is to offer students the opportunity to develop expertise and professional practices that are informed and driven by the science of human development and its theory and research.