Hypervalent iodine-catalyzed conjugate addition with sulfonamides Article (Faculty180)

cited authors

  • Ariyararhna, Jeewani P; Elizabeth, Ziegelmeyer C; Li, Wei


  • A hypervalent iodine-catalyzed conjugate addition with a sulfonamide nucleophile is described here. This reaction utilizes catalytic amounts of iodoarene and oxidant for the generation of the active hypervalent iodine catalyst. Activation of the enone substrate by the hypervalent iodine catalyst enables the nitrogen nucleophile addition that eventually forms a useful -aminocarbonyl product. This hypervalent iodine-catalyzed Aza-Michael reaction represents an interesting alternative to existing conjugate addition protocols.


publication date

  • 2021

published in

start page

  • 67

end page

  • 78


  • part iv