Intradialytic administration of daptomycin in end stage renal disease patients on hemodialysis Article (Faculty180)

cited authors

  • Salama, Noha N N; Segal, Jonathan H; Churchwell, Mariann D; Patel, Jignesh H; Gao, Lihong; Heung, Michael; Mueller, Bruce A

description

  • Infusion of intravenous antibiotics after hemodialysis (HD) may delay initiation of treatment for the next HD shift. Intradialytic administration of drugs such as vancomycin during the final hour of HD obviates these delays. Daptomycin has potent activity against Gram-positive bacteria, but the manufacturer recommends that the dose be infused after HD ends. This study determined the pharmacokinetics of intradialytically dosed daptomycin in patients with ESRD.

authors

publication date

  • 2009

published in

start page

  • 1190

end page

  • 4

volume

  • 4